FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020019966> ?p ?o ?g. }

• W2020019966 endingPage "131" @default.
• W2020019966 startingPage "123" @default.
• W2020019966 abstract "The effect of post-mortem delay on the stability of the protein subunits that combine to form NMDA and AMPA type glutamate receptors has been assessed in samples of human brain tissue. While most of the subunits (i.e. GluR1, GluR2/3, GluR4, NR1) appear to be stable for up to 18 h post-mortem, the NR2A and NR2B subunits appear to be proteolyzed rapidly following death. These results are consistent with the concept that the proteolytic products of NR2A and NR2B, although at smaller molecular sizes than the full-length protein, are all identifiable on Western blots. Thus, a method is proposed that allows for the estimation of the levels of these labile proteins even in samples obtained up to 18 h post-mortem. Using this method we have estimated the levels of all AMPA and NMDA receptor subunits in selected (i.e. hippocampus, frontal and entorhinal cortex) brain tissue samples obtained from control patients and patients who have died with Alzheimer's disease. Modest decreases in NMDA receptor subunits NR1, NR2A, and NR2B were found in the hippocampus and in frontal cortex while little or no change in any of these subunits were documented in entorhinal cortex. Subunits for AMPA receptors (GluR1, GluR2/3, and GluR4) appeared to show a generalized decrease in all these tissues. As a surrogate marker for overall decreases due to generalized neuronal cell death, levels of neuron-specific enolase were measured in all tissues and were found to be nearly identical in control and Alzheimer's brains." @default.
• W2020019966 created "2016-06-24" @default.
• W2020019966 creator A5001066277 @default.
• W2020019966 creator A5022548422 @default.
• W2020019966 creator A5042567256 @default.
• W2020019966 creator A5079401671 @default.
• W2020019966 creator A5084723460 @default.
• W2020019966 creator A5091878324 @default.
• W2020019966 date "2000-09-01" @default.
• W2020019966 modified "2023-09-30" @default.
• W2020019966 title "Effects of post-mortem delay on subunits of ionotropic glutamate receptors in human brain" @default.
• W2020019966 cites W1501388882 @default.
• W2020019966 cites W1548600249 @default.
• W2020019966 cites W1772604871 @default.
• W2020019966 cites W1969087751 @default.
• W2020019966 cites W1971695370 @default.
• W2020019966 cites W1972453936 @default.
• W2020019966 cites W1974553653 @default.
• W2020019966 cites W1996208391 @default.
• W2020019966 cites W1998263462 @default.
• W2020019966 cites W2017522100 @default.
• W2020019966 cites W2018362955 @default.
• W2020019966 cites W2018851715 @default.
• W2020019966 cites W2019444809 @default.
• W2020019966 cites W2023692020 @default.
• W2020019966 cites W2029276298 @default.
• W2020019966 cites W2044001266 @default.
• W2020019966 cites W2053980736 @default.
• W2020019966 cites W2059334396 @default.
• W2020019966 cites W2063200839 @default.
• W2020019966 cites W2069835093 @default.
• W2020019966 cites W2072328720 @default.
• W2020019966 cites W2073542991 @default.
• W2020019966 cites W2099597342 @default.
• W2020019966 cites W2101108802 @default.
• W2020019966 cites W2123779047 @default.
• W2020019966 cites W2129108032 @default.
• W2020019966 cites W2139619487 @default.
• W2020019966 cites W2146729934 @default.
• W2020019966 cites W2159864294 @default.
• W2020019966 cites W2336514795 @default.
• W2020019966 doi "https://doi.org/10.1016/s0169-328x(00)00111-x" @default.
• W2020019966 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11038245" @default.
• W2020019966 hasPublicationYear "2000" @default.
• W2020019966 type Work @default.
• W2020019966 sameAs 2020019966 @default.
• W2020019966 citedByCount "36" @default.
• W2020019966 countsByYear W20200199662014 @default.
• W2020019966 countsByYear W20200199662016 @default.
• W2020019966 countsByYear W20200199662017 @default.
• W2020019966 countsByYear W20200199662019 @default.
• W2020019966 countsByYear W20200199662020 @default.
• W2020019966 countsByYear W20200199662021 @default.
• W2020019966 countsByYear W20200199662022 @default.
• W2020019966 crossrefType "journal-article" @default.
• W2020019966 hasAuthorship W2020019966A5001066277 @default.
• W2020019966 hasAuthorship W2020019966A5022548422 @default.
• W2020019966 hasAuthorship W2020019966A5042567256 @default.
• W2020019966 hasAuthorship W2020019966A5079401671 @default.
• W2020019966 hasAuthorship W2020019966A5084723460 @default.
• W2020019966 hasAuthorship W2020019966A5091878324 @default.
• W2020019966 hasConcept C104292427 @default.
• W2020019966 hasConcept C104317684 @default.
• W2020019966 hasConcept C115955781 @default.
• W2020019966 hasConcept C126322002 @default.
• W2020019966 hasConcept C160268369 @default.
• W2020019966 hasConcept C169760540 @default.
• W2020019966 hasConcept C170493617 @default.
• W2020019966 hasConcept C2777348757 @default.
• W2020019966 hasConcept C2779134260 @default.
• W2020019966 hasConcept C2780715579 @default.
• W2020019966 hasConcept C2781161787 @default.
• W2020019966 hasConcept C502032728 @default.
• W2020019966 hasConcept C55493867 @default.
• W2020019966 hasConcept C61174792 @default.
• W2020019966 hasConcept C67018056 @default.
• W2020019966 hasConcept C71924100 @default.
• W2020019966 hasConcept C86803240 @default.
• W2020019966 hasConcept C95444343 @default.
• W2020019966 hasConceptScore W2020019966C104292427 @default.
• W2020019966 hasConceptScore W2020019966C104317684 @default.
• W2020019966 hasConceptScore W2020019966C115955781 @default.
• W2020019966 hasConceptScore W2020019966C126322002 @default.
• W2020019966 hasConceptScore W2020019966C160268369 @default.
• W2020019966 hasConceptScore W2020019966C169760540 @default.
• W2020019966 hasConceptScore W2020019966C170493617 @default.
• W2020019966 hasConceptScore W2020019966C2777348757 @default.
• W2020019966 hasConceptScore W2020019966C2779134260 @default.
• W2020019966 hasConceptScore W2020019966C2780715579 @default.
• W2020019966 hasConceptScore W2020019966C2781161787 @default.
• W2020019966 hasConceptScore W2020019966C502032728 @default.
• W2020019966 hasConceptScore W2020019966C55493867 @default.
• W2020019966 hasConceptScore W2020019966C61174792 @default.
• W2020019966 hasConceptScore W2020019966C67018056 @default.
• W2020019966 hasConceptScore W2020019966C71924100 @default.
• W2020019966 hasConceptScore W2020019966C86803240 @default.
• W2020019966 hasConceptScore W2020019966C95444343 @default.
• W2020019966 hasIssue "2" @default.

• next