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• W2020030336 abstract "Acute lymphoblastic leukemias with phenotypic characteristics of natural killer cell derived lineage are extremely uncommon. We identified an ALL with a phenotype consistent with an NK-cell of origin. The blasts underwent a proliferative response to r-IL2 in culture but showed no spontaneous or r-IL2 or γ-INF induced cytotoxicity. With r-IL2 stimulation however, the tumor cells demonstrated a dramatic acquisition of low density CD8 surface positivity and a loss of CD11b expression after short term culture. By comparison to ALL of B or T lineage, NK ALL likely represents an early stage of bone marrow derived NK-cell precursor." @default.
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• W2020030336 date "1989-01-01" @default.
• W2020030336 modified "2023-09-24" @default.
• W2020030336 title "Acute lymphoblastic leukemia of NK-cell lineage: Responses to IL-2" @default.
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• W2020030336 doi "https://doi.org/10.1016/0145-2126(89)90086-6" @default.
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