FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020043339> ?p ?o ?g. }

• W2020043339 endingPage "466" @default.
• W2020043339 startingPage "460" @default.
• W2020043339 abstract "Purpose of review Statins are the most prescribed medications worldwide with a proven ability to reduce major cardiovascular events. Recent data have revealed that statin therapy is associated with an increased risk for developing diabetes. We discuss the relevant data including newly published results, which demonstrate a dose-dependent association, we place these findings in clinical context and we consider clinical implications. Recent findings A recent meta-analysis of most major placebo and standard care-controlled statin trials with more than 90 000 participants confirmed that statin therapy was associated with a 9% increased risk of developing diabetes. Newly published data have confirmed a dose-dependent effect, with 12% higher risk of developing diabetes on intensive-dose statin therapy compared with moderate-dose therapy. In this meta-analysis, one additional patient developed diabetes for every three patients protected from a major cardiovascular event. The observation of higher diabetes risk remains unexplained at present, although studies in animal models suggest the possibility of impaired peripheral insulin signalling induced by statin therapy. Summary The cardiovascular benefits of statin therapy clearly outweigh the risk of developing diabetes. However, the data suggest the need to make patients aware of this possible risk and to monitor patients for development of diabetes, especially on intensive-dose therapy." @default.
• W2020043339 created "2016-06-24" @default.
• W2020043339 creator A5039985378 @default.
• W2020043339 creator A5078498803 @default.
• W2020043339 date "2011-12-01" @default.
• W2020043339 modified "2023-10-16" @default.
• W2020043339 title "Statins and the risk of new-onset diabetes" @default.
• W2020043339 cites W1500963439 @default.
• W2020043339 cites W1523152575 @default.
• W2020043339 cites W1546258268 @default.
• W2020043339 cites W1570093475 @default.
• W2020043339 cites W1978182417 @default.
• W2020043339 cites W1997020689 @default.
• W2020043339 cites W2016818962 @default.
• W2020043339 cites W2018711158 @default.
• W2020043339 cites W2019618316 @default.
• W2020043339 cites W2031185570 @default.
• W2020043339 cites W2042875425 @default.
• W2020043339 cites W2052703897 @default.
• W2020043339 cites W2061489988 @default.
• W2020043339 cites W2086139919 @default.
• W2020043339 cites W2100800328 @default.
• W2020043339 cites W2103108681 @default.
• W2020043339 cites W2107295258 @default.
• W2020043339 cites W2115169717 @default.
• W2020043339 cites W2116045728 @default.
• W2020043339 cites W2118667643 @default.
• W2020043339 cites W2126452437 @default.
• W2020043339 cites W2126678006 @default.
• W2020043339 cites W2129750583 @default.
• W2020043339 cites W2135631433 @default.
• W2020043339 cites W2137983259 @default.
• W2020043339 cites W2139168645 @default.
• W2020043339 cites W2146342944 @default.
• W2020043339 cites W2159449551 @default.
• W2020043339 cites W2159854507 @default.
• W2020043339 cites W2164089346 @default.
• W2020043339 cites W2165663485 @default.
• W2020043339 cites W2247997571 @default.
• W2020043339 cites W2317200002 @default.
• W2020043339 cites W2322095705 @default.
• W2020043339 cites W29474508 @default.
• W2020043339 cites W62443207 @default.
• W2020043339 doi "https://doi.org/10.1097/mol.0b013e32834b4994" @default.
• W2020043339 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21897230" @default.
• W2020043339 hasPublicationYear "2011" @default.
• W2020043339 type Work @default.
• W2020043339 sameAs 2020043339 @default.
• W2020043339 citedByCount "105" @default.
• W2020043339 countsByYear W20200433392012 @default.
• W2020043339 countsByYear W20200433392013 @default.
• W2020043339 countsByYear W20200433392014 @default.
• W2020043339 countsByYear W20200433392015 @default.
• W2020043339 countsByYear W20200433392016 @default.
• W2020043339 countsByYear W20200433392017 @default.
• W2020043339 countsByYear W20200433392018 @default.
• W2020043339 countsByYear W20200433392019 @default.
• W2020043339 countsByYear W20200433392020 @default.
• W2020043339 countsByYear W20200433392021 @default.
• W2020043339 countsByYear W20200433392022 @default.
• W2020043339 countsByYear W20200433392023 @default.
• W2020043339 crossrefType "journal-article" @default.
• W2020043339 hasAuthorship W2020043339A5039985378 @default.
• W2020043339 hasAuthorship W2020043339A5078498803 @default.
• W2020043339 hasConcept C126322002 @default.
• W2020043339 hasConcept C134018914 @default.
• W2020043339 hasConcept C142724271 @default.
• W2020043339 hasConcept C151730666 @default.
• W2020043339 hasConcept C177713679 @default.
• W2020043339 hasConcept C204787440 @default.
• W2020043339 hasConcept C27081682 @default.
• W2020043339 hasConcept C2776839432 @default.
• W2020043339 hasConcept C2777180221 @default.
• W2020043339 hasConcept C2779343474 @default.
• W2020043339 hasConcept C535046627 @default.
• W2020043339 hasConcept C555293320 @default.
• W2020043339 hasConcept C71924100 @default.
• W2020043339 hasConcept C86803240 @default.
• W2020043339 hasConceptScore W2020043339C126322002 @default.
• W2020043339 hasConceptScore W2020043339C134018914 @default.
• W2020043339 hasConceptScore W2020043339C142724271 @default.
• W2020043339 hasConceptScore W2020043339C151730666 @default.
• W2020043339 hasConceptScore W2020043339C177713679 @default.
• W2020043339 hasConceptScore W2020043339C204787440 @default.
• W2020043339 hasConceptScore W2020043339C27081682 @default.
• W2020043339 hasConceptScore W2020043339C2776839432 @default.
• W2020043339 hasConceptScore W2020043339C2777180221 @default.
• W2020043339 hasConceptScore W2020043339C2779343474 @default.
• W2020043339 hasConceptScore W2020043339C535046627 @default.
• W2020043339 hasConceptScore W2020043339C555293320 @default.
• W2020043339 hasConceptScore W2020043339C71924100 @default.
• W2020043339 hasConceptScore W2020043339C86803240 @default.
• W2020043339 hasIssue "6" @default.
• W2020043339 hasLocation W20200433391 @default.
• W2020043339 hasLocation W20200433392 @default.
• W2020043339 hasOpenAccess W2020043339 @default.
• W2020043339 hasPrimaryLocation W20200433391 @default.
• W2020043339 hasRelatedWork W1859326399 @default.

• next