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- W2020059900 abstract "We present a consensus document on the diagnosis and management of C1 inhibitor deficiency, a syndrome characterized clinically by recurrent episodes of angio-oedema. In hereditary angio-oedema, a rare autosomal dominant condition, C1 inhibitor function is reduced due to impaired transcription or production of non-functional protein. The diagnosis is confirmed by the presence of a low serum C4 and absent or greatly reduced C1 inhibitor level or function. The condition can cause fatal laryngeal oedema and features indistinguishable from gastrointestinal tract obstruction. Attacks can be precipitated by trauma, infection and other stimulants. Treatment is graded according to response and the clinical site of swelling. Acute treatment for severe attack is by infusion of C1 inhibitor concentrate and for minor attack attenuated androgens and/or tranexamic acid. Prophylactic treatment is by attenuated androgens and/or tranexamic acid. There are a number of new products in trial, including genetically engineered C1 esterase inhibitor, kallikrein inhibitor and bradykinin B2 receptor antagonist. Individual sections provide special advice with respect to diagnosis, management (prophylaxis and emergency care), special situations (childhood, pregnancy, contraception, travel and dental care) and service specification." @default.
- W2020059900 created "2016-06-24" @default.
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- W2020059900 date "2005-01-26" @default.
- W2020059900 modified "2023-10-18" @default.
- W2020059900 title "C1 inhibitor deficiency: consensus document" @default.
- W2020059900 cites W121728968 @default.
- W2020059900 cites W131193627 @default.
- W2020059900 cites W1488488217 @default.
- W2020059900 cites W1517293798 @default.
- W2020059900 cites W1557260127 @default.
- W2020059900 cites W1559340507 @default.
- W2020059900 cites W1579309523 @default.
- W2020059900 cites W15980340 @default.
- W2020059900 cites W174176327 @default.
- W2020059900 cites W188402869 @default.
- W2020059900 cites W1965532606 @default.
- W2020059900 cites W1965768055 @default.
- W2020059900 cites W1965938190 @default.
- W2020059900 cites W196618428 @default.
- W2020059900 cites W1966896554 @default.
- W2020059900 cites W1968088227 @default.
- W2020059900 cites W1968643303 @default.
- W2020059900 cites W1970621055 @default.
- W2020059900 cites W1971042333 @default.
- W2020059900 cites W1971508361 @default.
- W2020059900 cites W1972666210 @default.
- W2020059900 cites W1972964391 @default.
- W2020059900 cites W1974346983 @default.
- W2020059900 cites W1981626645 @default.
- W2020059900 cites W1982763532 @default.
- W2020059900 cites W1984506410 @default.
- W2020059900 cites W1984738685 @default.
- W2020059900 cites W1984852174 @default.
- W2020059900 cites W1986207725 @default.
- W2020059900 cites W1987353096 @default.
- W2020059900 cites W1988320682 @default.
- W2020059900 cites W1989289423 @default.
- W2020059900 cites W1990648595 @default.
- W2020059900 cites W1992146285 @default.
- W2020059900 cites W1992507985 @default.
- W2020059900 cites W1993411637 @default.
- W2020059900 cites W1993465482 @default.
- W2020059900 cites W1993870212 @default.
- W2020059900 cites W2000450248 @default.
- W2020059900 cites W2002502922 @default.
- W2020059900 cites W2004395480 @default.
- W2020059900 cites W2020264465 @default.
- W2020059900 cites W2022160378 @default.
- W2020059900 cites W2023210258 @default.
- W2020059900 cites W2024703122 @default.
- W2020059900 cites W2029556829 @default.
- W2020059900 cites W2031123437 @default.
- W2020059900 cites W2032910617 @default.
- W2020059900 cites W2034965507 @default.
- W2020059900 cites W2037961600 @default.
- W2020059900 cites W2043972408 @default.
- W2020059900 cites W2045411048 @default.
- W2020059900 cites W2047937242 @default.
- W2020059900 cites W2048904385 @default.
- W2020059900 cites W2050538873 @default.
- W2020059900 cites W2051794823 @default.
- W2020059900 cites W2053851252 @default.
- W2020059900 cites W2054653943 @default.
- W2020059900 cites W2055889100 @default.
- W2020059900 cites W2055963173 @default.
- W2020059900 cites W2057508718 @default.
- W2020059900 cites W2059092798 @default.
- W2020059900 cites W2061604493 @default.
- W2020059900 cites W2062934486 @default.
- W2020059900 cites W2063136806 @default.
- W2020059900 cites W2064340131 @default.
- W2020059900 cites W2064507837 @default.
- W2020059900 cites W2068252543 @default.
- W2020059900 cites W2068357925 @default.
- W2020059900 cites W2068999248 @default.
- W2020059900 cites W2074704061 @default.
- W2020059900 cites W2077580854 @default.
- W2020059900 cites W2077767519 @default.
- W2020059900 cites W2078264642 @default.
- W2020059900 cites W2079307330 @default.
- W2020059900 cites W2080074066 @default.
- W2020059900 cites W2081368903 @default.
- W2020059900 cites W2087966585 @default.
- W2020059900 cites W2088562706 @default.
- W2020059900 cites W2088853327 @default.
- W2020059900 cites W2091889001 @default.