Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020060786> ?p ?o ?g. }
- W2020060786 endingPage "1615" @default.
- W2020060786 startingPage "1610" @default.
- W2020060786 abstract "Numerous evidences demonstrated that type 1 diabetes (T1D) is due to a loss of immune tolerance to islet antigens, and CD8+ T cells play an important role in the development of T1D. Zinc Transporter 8 (ZnT8) has emerged in recent years as a target of disease-associated autoreactive T cells in human T1D. However, ZnT8-associated CTL specific-peptides have not been identified. In this study, we predicted and identified HLA-A*0201-restricted cytotoxic T lymphocyte (CTL) epitopes derived from ZnT8, and utilized it to immunize HLA-A2.1/Kb transgenic (Tg) mice. The results demonstrated that peptides of ZnT8 containing residues 107–115, 115–123 and 145–153 could elicit specific CTLs in vitro, and induce diabetes in mice. The results suggest that these specific peptides are novel HLA-A*0201-restricted CTL epitopes, and could have therapeutic potential in preventing of T1D disease." @default.
- W2020060786 created "2016-06-24" @default.
- W2020060786 creator A5015735546 @default.
- W2020060786 creator A5049407947 @default.
- W2020060786 creator A5053122768 @default.
- W2020060786 creator A5071529293 @default.
- W2020060786 creator A5077604881 @default.
- W2020060786 creator A5078873353 @default.
- W2020060786 creator A5085514860 @default.
- W2020060786 creator A5089157307 @default.
- W2020060786 date "2013-03-01" @default.
- W2020060786 modified "2023-10-16" @default.
- W2020060786 title "Identification of novel HLA-A*0201-restricted cytotoxic T lymphocyte epitopes from Zinc Transporter 8" @default.
- W2020060786 cites W1494276623 @default.
- W2020060786 cites W1562228673 @default.
- W2020060786 cites W1585595725 @default.
- W2020060786 cites W1826514729 @default.
- W2020060786 cites W1977846064 @default.
- W2020060786 cites W1989257844 @default.
- W2020060786 cites W1993312496 @default.
- W2020060786 cites W1993779561 @default.
- W2020060786 cites W1994048581 @default.
- W2020060786 cites W1996018366 @default.
- W2020060786 cites W1996775525 @default.
- W2020060786 cites W1997172625 @default.
- W2020060786 cites W2002364985 @default.
- W2020060786 cites W2005227623 @default.
- W2020060786 cites W2006797240 @default.
- W2020060786 cites W2011614956 @default.
- W2020060786 cites W2018790303 @default.
- W2020060786 cites W2019028906 @default.
- W2020060786 cites W2021490947 @default.
- W2020060786 cites W2029959553 @default.
- W2020060786 cites W2044720900 @default.
- W2020060786 cites W2051774987 @default.
- W2020060786 cites W2053608295 @default.
- W2020060786 cites W2063275638 @default.
- W2020060786 cites W2064139721 @default.
- W2020060786 cites W2075745554 @default.
- W2020060786 cites W2085209807 @default.
- W2020060786 cites W2088681775 @default.
- W2020060786 cites W2096420254 @default.
- W2020060786 cites W2099632598 @default.
- W2020060786 cites W2100992652 @default.
- W2020060786 cites W2130595746 @default.
- W2020060786 cites W2131740166 @default.
- W2020060786 cites W2133070194 @default.
- W2020060786 cites W2137761662 @default.
- W2020060786 cites W2144576542 @default.
- W2020060786 cites W2149765115 @default.
- W2020060786 cites W2166831581 @default.
- W2020060786 cites W4239067649 @default.
- W2020060786 doi "https://doi.org/10.1016/j.vaccine.2012.12.008" @default.
- W2020060786 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23246542" @default.
- W2020060786 hasPublicationYear "2013" @default.
- W2020060786 type Work @default.
- W2020060786 sameAs 2020060786 @default.
- W2020060786 citedByCount "17" @default.
- W2020060786 countsByYear W20200607862014 @default.
- W2020060786 countsByYear W20200607862015 @default.
- W2020060786 countsByYear W20200607862016 @default.
- W2020060786 countsByYear W20200607862017 @default.
- W2020060786 countsByYear W20200607862018 @default.
- W2020060786 countsByYear W20200607862019 @default.
- W2020060786 countsByYear W20200607862020 @default.
- W2020060786 crossrefType "journal-article" @default.
- W2020060786 hasAuthorship W2020060786A5015735546 @default.
- W2020060786 hasAuthorship W2020060786A5049407947 @default.
- W2020060786 hasAuthorship W2020060786A5053122768 @default.
- W2020060786 hasAuthorship W2020060786A5071529293 @default.
- W2020060786 hasAuthorship W2020060786A5077604881 @default.
- W2020060786 hasAuthorship W2020060786A5078873353 @default.
- W2020060786 hasAuthorship W2020060786A5085514860 @default.
- W2020060786 hasAuthorship W2020060786A5089157307 @default.
- W2020060786 hasConcept C147483822 @default.
- W2020060786 hasConcept C147969180 @default.
- W2020060786 hasConcept C154317977 @default.
- W2020060786 hasConcept C167672396 @default.
- W2020060786 hasConcept C188280979 @default.
- W2020060786 hasConcept C195616568 @default.
- W2020060786 hasConcept C202751555 @default.
- W2020060786 hasConcept C203014093 @default.
- W2020060786 hasConcept C55493867 @default.
- W2020060786 hasConcept C86803240 @default.
- W2020060786 hasConcept C8891405 @default.
- W2020060786 hasConceptScore W2020060786C147483822 @default.
- W2020060786 hasConceptScore W2020060786C147969180 @default.
- W2020060786 hasConceptScore W2020060786C154317977 @default.
- W2020060786 hasConceptScore W2020060786C167672396 @default.
- W2020060786 hasConceptScore W2020060786C188280979 @default.
- W2020060786 hasConceptScore W2020060786C195616568 @default.
- W2020060786 hasConceptScore W2020060786C202751555 @default.
- W2020060786 hasConceptScore W2020060786C203014093 @default.
- W2020060786 hasConceptScore W2020060786C55493867 @default.
- W2020060786 hasConceptScore W2020060786C86803240 @default.
- W2020060786 hasConceptScore W2020060786C8891405 @default.
- W2020060786 hasIssue "12" @default.
- W2020060786 hasLocation W20200607861 @default.