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- W2020062150 abstract "The possible interaction between vasopressin and monoamines in the regulation of exploratory behaviour was investigated. Treatment with lysine-vasopressin (LVP) influenced this behaviour. In particular, the investigative activity was enhanced. The dose-response relationship of LVP was non-linear. The catecholamine synthesis inhibitor alpha-methyl-p-tyrosine (alpha-MT, 100 mg/kg) also increased the investigative activity, indicating a suppressive influence of catecholamines on this behaviour. alpha-MT pretreatment potentiated the effect of LVP within certain dose levels. The dose-response relationship for the peptide effect on the investigative activity was shifted towards the left. Treatment with the serotonin biosynthesis inhibitor para-chloro-phenylalanine (PCPA) (100 + 50 + 50 mg/kg) also enhanced the investigative behaviour and potentiated the action of LVP similarly to alpha-MT. It is suggested that the action of LVP on the exploratory behaviour in rats can be modified by monoamines." @default.
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- W2020062150 title "Facilitatory effects of monoamine synthesis inhibitors on lysine-vasopressin induced changes in the exploratory behaviour pattern of male rats" @default.
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- W2020062150 doi "https://doi.org/10.1016/s0091-3057(84)80065-9" @default.
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