FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020062911> ?p ?o ?g. }

• W2020062911 endingPage "276" @default.
• W2020062911 startingPage "267" @default.
• W2020062911 abstract "Extensive sequencing of genomic 4f-rnp and 15 cDNA clones isolated from libraries of 0–4-h embryos, pupae, and adult heads from Drosophila melanogaster has enabled identification of factors resulting in transcript sequence diversity. The 4f-rnp gene contains eight small introns. Among non-edited cDNAs, one transcript class potentially encodes a 943-amino-acid protein, within which several motifs are predicted, including a single C-terminal RNA-binding domain. Intron 5 is retained in all cDNAs examined except for a pupal cDNA, where it is excised. This potentially introduces an in-frame stop codon and predicts a truncated protein of 639 amino acids. One adult head transcript class is edited, some 31% of As being converted to Gs exclusive of edits within introns. An edit site in intron 4 changes a canonical 3′-terminal AG to GG, which interferes with splicing and is predicted to introduce a stop codon. A potential editing substrate recognition element in 4f-rnp contains the weak consensus sequence: 5′–G–G–G–N–A–A–G–3′, which may interact with double-stranded RNA adenosine deaminase following pairing of 4f-rnp mRNA with an antisense transcript. It is possible that extensive editing in 4f-rnp destabilizes transcripts and thus provides a novel mechanism for post-transcriptional control of gene expression, although resolution of this point will require study of additional edited transcripts." @default.
• W2020062911 created "2016-06-24" @default.
• W2020062911 creator A5007301307 @default.
• W2020062911 creator A5014033433 @default.
• W2020062911 creator A5039661866 @default.
• W2020062911 creator A5081007364 @default.
• W2020062911 date "1997-12-01" @default.
• W2020062911 modified "2023-10-18" @default.
• W2020062911 title "RNA editing and alternative splicing generate mRNA transcript diversity from the Drosophila 4f-rnp locus" @default.
• W2020062911 cites W115531509 @default.
• W2020062911 cites W126612449 @default.
• W2020062911 cites W1842576247 @default.
• W2020062911 cites W1965750059 @default.
• W2020062911 cites W1967554461 @default.
• W2020062911 cites W1974450466 @default.
• W2020062911 cites W1982848096 @default.
• W2020062911 cites W1983886862 @default.
• W2020062911 cites W1986923087 @default.
• W2020062911 cites W1987956539 @default.
• W2020062911 cites W1998119535 @default.
• W2020062911 cites W2002554363 @default.
• W2020062911 cites W2012630877 @default.
• W2020062911 cites W2014832270 @default.
• W2020062911 cites W2019789361 @default.
• W2020062911 cites W2021697666 @default.
• W2020062911 cites W2022236187 @default.
• W2020062911 cites W2022650803 @default.
• W2020062911 cites W2028415958 @default.
• W2020062911 cites W2031494103 @default.
• W2020062911 cites W2034890717 @default.
• W2020062911 cites W2036447800 @default.
• W2020062911 cites W2047791752 @default.
• W2020062911 cites W2051490611 @default.
• W2020062911 cites W2052800266 @default.
• W2020062911 cites W2056025481 @default.
• W2020062911 cites W2057461568 @default.
• W2020062911 cites W2063450941 @default.
• W2020062911 cites W2068861284 @default.
• W2020062911 cites W2074562954 @default.
• W2020062911 cites W2087847177 @default.
• W2020062911 cites W2125201432 @default.
• W2020062911 cites W2132017330 @default.
• W2020062911 cites W2138270253 @default.
• W2020062911 cites W2143824656 @default.
• W2020062911 cites W2144148386 @default.
• W2020062911 cites W214526914 @default.
• W2020062911 cites W1993044477 @default.
• W2020062911 doi "https://doi.org/10.1016/s0378-1119(97)00465-4" @default.
• W2020062911 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9434193" @default.
• W2020062911 hasPublicationYear "1997" @default.
• W2020062911 type Work @default.
• W2020062911 sameAs 2020062911 @default.
• W2020062911 citedByCount "25" @default.
• W2020062911 countsByYear W20200629112012 @default.
• W2020062911 countsByYear W20200629112013 @default.
• W2020062911 countsByYear W20200629112015 @default.
• W2020062911 countsByYear W20200629112016 @default.
• W2020062911 countsByYear W20200629112018 @default.
• W2020062911 countsByYear W20200629112020 @default.
• W2020062911 crossrefType "journal-article" @default.
• W2020062911 hasAuthorship W2020062911A5007301307 @default.
• W2020062911 hasAuthorship W2020062911A5014033433 @default.
• W2020062911 hasAuthorship W2020062911A5039661866 @default.
• W2020062911 hasAuthorship W2020062911A5081007364 @default.
• W2020062911 hasConcept C104317684 @default.
• W2020062911 hasConcept C105580179 @default.
• W2020062911 hasConcept C141231307 @default.
• W2020062911 hasConcept C153911025 @default.
• W2020062911 hasConcept C176990463 @default.
• W2020062911 hasConcept C187882448 @default.
• W2020062911 hasConcept C194583182 @default.
• W2020062911 hasConcept C21786251 @default.
• W2020062911 hasConcept C54355233 @default.
• W2020062911 hasConcept C54458228 @default.
• W2020062911 hasConcept C67705224 @default.
• W2020062911 hasConcept C86803240 @default.
• W2020062911 hasConcept C87253356 @default.
• W2020062911 hasConcept C94671646 @default.
• W2020062911 hasConceptScore W2020062911C104317684 @default.
• W2020062911 hasConceptScore W2020062911C105580179 @default.
• W2020062911 hasConceptScore W2020062911C141231307 @default.
• W2020062911 hasConceptScore W2020062911C153911025 @default.
• W2020062911 hasConceptScore W2020062911C176990463 @default.
• W2020062911 hasConceptScore W2020062911C187882448 @default.
• W2020062911 hasConceptScore W2020062911C194583182 @default.
• W2020062911 hasConceptScore W2020062911C21786251 @default.
• W2020062911 hasConceptScore W2020062911C54355233 @default.
• W2020062911 hasConceptScore W2020062911C54458228 @default.
• W2020062911 hasConceptScore W2020062911C67705224 @default.
• W2020062911 hasConceptScore W2020062911C86803240 @default.
• W2020062911 hasConceptScore W2020062911C87253356 @default.
• W2020062911 hasConceptScore W2020062911C94671646 @default.
• W2020062911 hasIssue "1-2" @default.
• W2020062911 hasLocation W20200629111 @default.
• W2020062911 hasLocation W20200629112 @default.
• W2020062911 hasOpenAccess W2020062911 @default.
• W2020062911 hasPrimaryLocation W20200629111 @default.
• W2020062911 hasRelatedWork W1965266937 @default.

• next