FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020080372> ?p ?o ?g. }

• W2020080372 endingPage "90" @default.
• W2020080372 startingPage "84" @default.
• W2020080372 abstract "Histone lysine methylation (HKM) is an epigenetic change that establishes cell-specific gene expression and determines cell fates. In this study, we investigated the expression patterns of histone H3 lysine 9 methyltransferases (H3K9MTases) G9a (euchromatic histone lysine N-methyltransferase 2, Ehmt2), GLP (euchromatic histone lysine N-methyltransferase 1, Ehmt1), SETDB1 (SET domain, bifurcated 1), PRDM2 (PR domain containing 2), SUV39H1 (suppressor of variegation 3-9 homolog 1), and SUV39H2, as well as the distribution of 3 types of HKM at histone H3 lysine 9: mono- (H3K9me1), di- (H3K9me2), or tri-methylation (H3K9me3), during mouse growth plate development. In the forelimb cartilage primordial at embryonic day 12.5 (E12.5), none of the H3K9MTases were detected and H3K9me1, H3K9me2, and H3K9me3 were scarcely detected. At E14.5, the H3K9MTases were expressed at low levels in proliferating chondrocytes and at high levels in prehypertrophic and hypertrophic chondrocytes. Among the H3K9 methylations, H3K9me1 and H3K9me3 were markedly noted in these chondrocytes. At E16.5, G9, GLP, SETDB1, PRDM2, SUV39H1, and SUV39H2, as well as H3K9me1, H3K9me2, and H3K9me3, were detected in prehypertrophic and hypertrophic chondrocytes in the growth plate. Western blotting and real-time quantitative polymerase chain reaction analysis revealed the distributions of G9 and GLP proteins and the expression of all the H3K9MTase mRNAs in prehypertrophic and hypertrophic chondrocytes. These data suggest that H3K9 methyltransferases are predominantly expressed in prehypertrophic and hypertrophic chondrocytes, and that they could be involved in the regulation of gene expression and progression of chondrocyte differentiation by affecting the methylation state of histone H3 lysine 9 in the mouse growth plate." @default.
• W2020080372 created "2016-06-24" @default.
• W2020080372 creator A5004937355 @default.
• W2020080372 creator A5006075587 @default.
• W2020080372 creator A5008935686 @default.
• W2020080372 creator A5021449949 @default.
• W2020080372 creator A5052996512 @default.
• W2020080372 creator A5070274286 @default.
• W2020080372 creator A5081454261 @default.
• W2020080372 date "2013-03-01" @default.
• W2020080372 modified "2023-10-09" @default.
• W2020080372 title "Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development" @default.
• W2020080372 cites W1981071130 @default.
• W2020080372 cites W2002852310 @default.
• W2020080372 cites W2009858080 @default.
• W2020080372 cites W2040155058 @default.
• W2020080372 cites W2040891039 @default.
• W2020080372 cites W2044917002 @default.
• W2020080372 cites W2055977825 @default.
• W2020080372 cites W2059347029 @default.
• W2020080372 cites W2064297857 @default.
• W2020080372 cites W2073866320 @default.
• W2020080372 cites W2091884937 @default.
• W2020080372 cites W2092794927 @default.
• W2020080372 cites W2095626300 @default.
• W2020080372 cites W2119036640 @default.
• W2020080372 cites W2148811260 @default.
• W2020080372 cites W2155149522 @default.
• W2020080372 cites W2163771097 @default.
• W2020080372 cites W2166083262 @default.
• W2020080372 cites W2168991217 @default.
• W2020080372 cites W2747900948 @default.
• W2020080372 doi "https://doi.org/10.1016/j.gep.2013.01.002" @default.
• W2020080372 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23333759" @default.
• W2020080372 hasPublicationYear "2013" @default.
• W2020080372 type Work @default.
• W2020080372 sameAs 2020080372 @default.
• W2020080372 citedByCount "14" @default.
• W2020080372 countsByYear W20200803722014 @default.
• W2020080372 countsByYear W20200803722015 @default.
• W2020080372 countsByYear W20200803722016 @default.
• W2020080372 countsByYear W20200803722018 @default.
• W2020080372 countsByYear W20200803722019 @default.
• W2020080372 countsByYear W20200803722020 @default.
• W2020080372 crossrefType "journal-article" @default.
• W2020080372 hasAuthorship W2020080372A5004937355 @default.
• W2020080372 hasAuthorship W2020080372A5006075587 @default.
• W2020080372 hasAuthorship W2020080372A5008935686 @default.
• W2020080372 hasAuthorship W2020080372A5021449949 @default.
• W2020080372 hasAuthorship W2020080372A5052996512 @default.
• W2020080372 hasAuthorship W2020080372A5070274286 @default.
• W2020080372 hasAuthorship W2020080372A5081454261 @default.
• W2020080372 hasConcept C104317684 @default.
• W2020080372 hasConcept C150194340 @default.
• W2020080372 hasConcept C150425827 @default.
• W2020080372 hasConcept C153911025 @default.
• W2020080372 hasConcept C190727270 @default.
• W2020080372 hasConcept C22709980 @default.
• W2020080372 hasConcept C2776745794 @default.
• W2020080372 hasConcept C2779085176 @default.
• W2020080372 hasConcept C33288867 @default.
• W2020080372 hasConcept C50171091 @default.
• W2020080372 hasConcept C54355233 @default.
• W2020080372 hasConcept C64927066 @default.
• W2020080372 hasConcept C86803240 @default.
• W2020080372 hasConcept C91965660 @default.
• W2020080372 hasConcept C95444343 @default.
• W2020080372 hasConceptScore W2020080372C104317684 @default.
• W2020080372 hasConceptScore W2020080372C150194340 @default.
• W2020080372 hasConceptScore W2020080372C150425827 @default.
• W2020080372 hasConceptScore W2020080372C153911025 @default.
• W2020080372 hasConceptScore W2020080372C190727270 @default.
• W2020080372 hasConceptScore W2020080372C22709980 @default.
• W2020080372 hasConceptScore W2020080372C2776745794 @default.
• W2020080372 hasConceptScore W2020080372C2779085176 @default.
• W2020080372 hasConceptScore W2020080372C33288867 @default.
• W2020080372 hasConceptScore W2020080372C50171091 @default.
• W2020080372 hasConceptScore W2020080372C54355233 @default.
• W2020080372 hasConceptScore W2020080372C64927066 @default.
• W2020080372 hasConceptScore W2020080372C86803240 @default.
• W2020080372 hasConceptScore W2020080372C91965660 @default.
• W2020080372 hasConceptScore W2020080372C95444343 @default.
• W2020080372 hasFunder F4320320912 @default.
• W2020080372 hasIssue "3-4" @default.
• W2020080372 hasLocation W20200803721 @default.
• W2020080372 hasLocation W20200803722 @default.
• W2020080372 hasOpenAccess W2020080372 @default.
• W2020080372 hasPrimaryLocation W20200803721 @default.
• W2020080372 hasRelatedWork W1986693701 @default.
• W2020080372 hasRelatedWork W1999337138 @default.
• W2020080372 hasRelatedWork W2058447361 @default.
• W2020080372 hasRelatedWork W2107073512 @default.
• W2020080372 hasRelatedWork W2120180066 @default.
• W2020080372 hasRelatedWork W2761879451 @default.
• W2020080372 hasRelatedWork W2790280998 @default.
• W2020080372 hasRelatedWork W4297784020 @default.
• W2020080372 hasRelatedWork W4366997524 @default.
• W2020080372 hasRelatedWork W4381089803 @default.

• next