FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020102147> ?p ?o ?g. }

• W2020102147 endingPage "121" @default.
• W2020102147 startingPage "114" @default.
• W2020102147 abstract "Posttraumatic stress disorder (PTSD) has been associated with neurocognitive deficits, such as impaired verbal memory and executive functioning. Less is known about executive function and the role of comorbid depression in PTSD. Recently, studies have shown that verbal memory impairments may be associated with comorbid depressive symptoms, but their role in executive function impairments is still unclear.To examine several domains of executive functioning in PTSD and the potentially mediating role of comorbid depressive symptoms in the relationship between executive function and PTSD.Executive functioning was assessed in 28 PTSD patients and 28 matched trauma-exposed controls. The Cambridge Neuropsychological Test Automated Battery (CANTAB) with subtests measuring response inhibition (SST), flexibility/set shifting (IED), planning/working memory (OTS) and spatial working memory (SWM) was administered in PTSD patients and trauma-exposed controls. Regression analyses were used to assess the predictive factor of PTSD symptoms (CAPS) and depressive symptoms (HADS-D) in relation to executive function when taking into account the type of trauma. Pearson's correlations were used to examine the association between PTSD symptom clusters (CAPS) and executive function. The mediating effects of depression and PTSD were assessed using regression coefficients and the Sobel's test for mediation.Our findings indicate that PTSD patients performed significantly worse on executive function than trauma-exposed controls in all domains assessed. PTSD symptoms contributed to executive functioning impairments (SST median correct, IED total errors, OTS latency to correct, SWM total errors and SWM strategy). Adding depressive symptoms to the model attenuated these effects. PTSD symptom clusters 'numbing' and to a lesser extent 'avoidance' were more frequently associated with worse executive function (i.e., IED total errors, OTS latency to correct and SWM total errors) than 'reexperiencing' and 'hyperarousal'. Depressive symptoms mediated the relation between PTSD and executive function on some executive function measures (IED total errors and OTS latency to correct), whereas PTSD did not mediate the relation between depression and executive function.PTSD patients perform worse on executive function. The impairments seem to be mostly associated with the less specific PTSD symptom cluster of 'numbing'. Depressive symptoms seem to mediate the relationship between PTSD and executive function. These findings may have clinical implications with regard to treatment indication and prognosis." @default.
• W2020102147 created "2016-06-24" @default.
• W2020102147 creator A5000974993 @default.
• W2020102147 creator A5010458603 @default.
• W2020102147 creator A5087314382 @default.
• W2020102147 creator A5090003238 @default.
• W2020102147 date "2014-07-01" @default.
• W2020102147 modified "2023-10-16" @default.
• W2020102147 title "Executive function in posttraumatic stress disorder (PTSD) and the influence of comorbid depression" @default.
• W2020102147 cites W1985314680 @default.
• W2020102147 cites W1985987720 @default.
• W2020102147 cites W1996010601 @default.
• W2020102147 cites W2004651961 @default.
• W2020102147 cites W2009211323 @default.
• W2020102147 cites W2013571632 @default.
• W2020102147 cites W2020020413 @default.
• W2020102147 cites W2023349410 @default.
• W2020102147 cites W2025147307 @default.
• W2020102147 cites W2028620178 @default.
• W2020102147 cites W2031220046 @default.
• W2020102147 cites W2032465095 @default.
• W2020102147 cites W2034225478 @default.
• W2020102147 cites W2039854536 @default.
• W2020102147 cites W2055042327 @default.
• W2020102147 cites W2062607372 @default.
• W2020102147 cites W2067658969 @default.
• W2020102147 cites W2068705310 @default.
• W2020102147 cites W2074932610 @default.
• W2020102147 cites W2080243976 @default.
• W2020102147 cites W2089158781 @default.
• W2020102147 cites W2106557234 @default.
• W2020102147 cites W2109105506 @default.
• W2020102147 cites W2110608362 @default.
• W2020102147 cites W2115116930 @default.
• W2020102147 cites W2116486172 @default.
• W2020102147 cites W2118236591 @default.
• W2020102147 cites W2122557837 @default.
• W2020102147 cites W2132304425 @default.
• W2020102147 cites W2136170254 @default.
• W2020102147 cites W2137484734 @default.
• W2020102147 cites W2144105446 @default.
• W2020102147 cites W2145402612 @default.
• W2020102147 cites W2148997797 @default.
• W2020102147 cites W2156255736 @default.
• W2020102147 cites W2159812249 @default.
• W2020102147 cites W2162664083 @default.
• W2020102147 cites W2166281097 @default.
• W2020102147 cites W4230642005 @default.
• W2020102147 cites W4249129794 @default.
• W2020102147 doi "https://doi.org/10.1016/j.nlm.2014.01.003" @default.
• W2020102147 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24440596" @default.
• W2020102147 hasPublicationYear "2014" @default.
• W2020102147 type Work @default.
• W2020102147 sameAs 2020102147 @default.
• W2020102147 citedByCount "78" @default.
• W2020102147 countsByYear W20201021472013 @default.
• W2020102147 countsByYear W20201021472014 @default.
• W2020102147 countsByYear W20201021472015 @default.
• W2020102147 countsByYear W20201021472016 @default.
• W2020102147 countsByYear W20201021472017 @default.
• W2020102147 countsByYear W20201021472018 @default.
• W2020102147 countsByYear W20201021472019 @default.
• W2020102147 countsByYear W20201021472020 @default.
• W2020102147 countsByYear W20201021472021 @default.
• W2020102147 countsByYear W20201021472022 @default.
• W2020102147 countsByYear W20201021472023 @default.
• W2020102147 crossrefType "journal-article" @default.
• W2020102147 hasAuthorship W2020102147A5000974993 @default.
• W2020102147 hasAuthorship W2020102147A5010458603 @default.
• W2020102147 hasAuthorship W2020102147A5087314382 @default.
• W2020102147 hasAuthorship W2020102147A5090003238 @default.
• W2020102147 hasConcept C118552586 @default.
• W2020102147 hasConcept C139719470 @default.
• W2020102147 hasConcept C14216870 @default.
• W2020102147 hasConcept C15744967 @default.
• W2020102147 hasConcept C162324750 @default.
• W2020102147 hasConcept C169900460 @default.
• W2020102147 hasConcept C172467417 @default.
• W2020102147 hasConcept C21963081 @default.
• W2020102147 hasConcept C2775968953 @default.
• W2020102147 hasConcept C2776867660 @default.
• W2020102147 hasConcept C2779338893 @default.
• W2020102147 hasConcept C2779985164 @default.
• W2020102147 hasConcept C43729271 @default.
• W2020102147 hasConcept C66102695 @default.
• W2020102147 hasConcept C70410870 @default.
• W2020102147 hasConceptScore W2020102147C118552586 @default.
• W2020102147 hasConceptScore W2020102147C139719470 @default.
• W2020102147 hasConceptScore W2020102147C14216870 @default.
• W2020102147 hasConceptScore W2020102147C15744967 @default.
• W2020102147 hasConceptScore W2020102147C162324750 @default.
• W2020102147 hasConceptScore W2020102147C169900460 @default.
• W2020102147 hasConceptScore W2020102147C172467417 @default.
• W2020102147 hasConceptScore W2020102147C21963081 @default.
• W2020102147 hasConceptScore W2020102147C2775968953 @default.
• W2020102147 hasConceptScore W2020102147C2776867660 @default.
• W2020102147 hasConceptScore W2020102147C2779338893 @default.
• W2020102147 hasConceptScore W2020102147C2779985164 @default.

• next