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- W2020102154 abstract "Low respiratory infections (LRI) are common in patients with dementia, and account for two thirds of deaths in this population. Prognosis, including long-term mortality, is important because lack of knowledge could foster underuse of palliative care services for those who would benefit and overuse of aggressive therapies for those who are unlikely to recover. Aim of the study is to investigate the association between LRI and three-month mortality in elderly patients with and without dementia. In a retrospective study 3300 newly admitted to our Sub-Intensive Care Unit, were selected and subdivided in 4 groups: 2566 patients without LRI and dementia, 265 with LRI and without dementia, 345 without LRI and with dementia, and 124 with LRI and dementia. Measurements were: age, gender, Barthel Index detected 2 weeks before admission and on admission, APACHE-II, Charlson Index, were assessed. Cognitive impairment was evaluated with MMSE and severe dementia as MMSE<12. LRI was diagnosed by clinical signs and chest radiography and treatment done according to the American Thoracic Society guidelines. At a 3-month follow up 46% of subjects diagnosed with severe dementia and LTI are still alive. Currently we are unable to demonstrate if these results are due to a clinical effect or to the “vis medicatrix naturae” (Healing Power of Nature). Whatever the therapeutic options in these patients, first of all we must provide a palliative care for pain and other subjectively distressing conditions." @default.
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- W2020102154 date "2008-07-01" @default.
- W2020102154 modified "2023-09-25" @default.
- W2020102154 title "P4-143: Dementia and mortality in elderly patients with low respiratory infections" @default.
- W2020102154 doi "https://doi.org/10.1016/j.jalz.2008.05.2209" @default.
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