Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020106149> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W2020106149 endingPage "e4" @default.
- W2020106149 startingPage "e4" @default.
- W2020106149 abstract "<h3>Background</h3> A number of epidemiologic studies show a decreased risk of non-melanoma cancer in Parkinson9s disease (PD). Cigarette smoking is less prevalent in PD and hence the risk of smoking related neoplasia such as lung and colon would be expected to be decreased in PD. A link is shown between decreased physical activity and colorectal cancer. Increased dietary intake of iron increases colorectal cancer risk and iron deposition in the basal ganglia is a feature of PD. Thus common mechanisms may be involved in both disorders. Our study looks at a cohort of surgically treated PD patients to see if there is an altered risk of colorectal cancer among them. <h3>Method</h3> In our population of patients fitted with a deep brain stimulator between 2002 and 2010, we searched for causes of death confirmed against death certificates and a histological diagnosis of colorectal cancer in the patient records. <h3>Results</h3> Of 22 patients who had died, 3 had a diagnosis colorectal cancer. 1 more died of a carcinoembryonic antigen positive cancer of unknown origin. <h3>Discussion</h3> From UK national statistics, colorectal cancer accounts for between 2.7 and 3.2% of all deaths. Although the small number of deaths in our cohort requires careful interpretation of the results, 14% of our cohort having a diagnosis of colorectal cancer suggests that the lifetime risk of colorectal cancer is not reduced in PD patients. This observation merits further investigation in a larger cohort of PD patients." @default.
- W2020106149 created "2016-06-24" @default.
- W2020106149 creator A5054069514 @default.
- W2020106149 creator A5069295590 @default.
- W2020106149 creator A5078876581 @default.
- W2020106149 creator A5084818860 @default.
- W2020106149 creator A5086774714 @default.
- W2020106149 date "2011-08-07" @default.
- W2020106149 modified "2023-09-26" @default.
- W2020106149 title "PO.08 Colorectal cancer risk in Parkinson's disease: insights from a surgically treated cohort" @default.
- W2020106149 doi "https://doi.org/10.1136/jnnp-2011-300645.20" @default.
- W2020106149 hasPublicationYear "2011" @default.
- W2020106149 type Work @default.
- W2020106149 sameAs 2020106149 @default.
- W2020106149 citedByCount "0" @default.
- W2020106149 crossrefType "journal-article" @default.
- W2020106149 hasAuthorship W2020106149A5054069514 @default.
- W2020106149 hasAuthorship W2020106149A5069295590 @default.
- W2020106149 hasAuthorship W2020106149A5078876581 @default.
- W2020106149 hasAuthorship W2020106149A5084818860 @default.
- W2020106149 hasAuthorship W2020106149A5086774714 @default.
- W2020106149 hasConcept C121608353 @default.
- W2020106149 hasConcept C126322002 @default.
- W2020106149 hasConcept C143998085 @default.
- W2020106149 hasConcept C201903717 @default.
- W2020106149 hasConcept C2777387746 @default.
- W2020106149 hasConcept C2779134260 @default.
- W2020106149 hasConcept C2908647359 @default.
- W2020106149 hasConcept C526805850 @default.
- W2020106149 hasConcept C71924100 @default.
- W2020106149 hasConcept C72563966 @default.
- W2020106149 hasConcept C99454951 @default.
- W2020106149 hasConceptScore W2020106149C121608353 @default.
- W2020106149 hasConceptScore W2020106149C126322002 @default.
- W2020106149 hasConceptScore W2020106149C143998085 @default.
- W2020106149 hasConceptScore W2020106149C201903717 @default.
- W2020106149 hasConceptScore W2020106149C2777387746 @default.
- W2020106149 hasConceptScore W2020106149C2779134260 @default.
- W2020106149 hasConceptScore W2020106149C2908647359 @default.
- W2020106149 hasConceptScore W2020106149C526805850 @default.
- W2020106149 hasConceptScore W2020106149C71924100 @default.
- W2020106149 hasConceptScore W2020106149C72563966 @default.
- W2020106149 hasConceptScore W2020106149C99454951 @default.
- W2020106149 hasIssue "9" @default.
- W2020106149 hasLocation W20201061491 @default.
- W2020106149 hasOpenAccess W2020106149 @default.
- W2020106149 hasPrimaryLocation W20201061491 @default.
- W2020106149 hasRelatedWork W2122377763 @default.
- W2020106149 hasRelatedWork W2158346116 @default.
- W2020106149 hasRelatedWork W2187306220 @default.
- W2020106149 hasRelatedWork W2381416288 @default.
- W2020106149 hasRelatedWork W2412066538 @default.
- W2020106149 hasRelatedWork W2599866838 @default.
- W2020106149 hasRelatedWork W2885311146 @default.
- W2020106149 hasRelatedWork W2887848930 @default.
- W2020106149 hasRelatedWork W3025365092 @default.
- W2020106149 hasRelatedWork W4321610511 @default.
- W2020106149 hasVolume "82" @default.
- W2020106149 isParatext "false" @default.
- W2020106149 isRetracted "false" @default.
- W2020106149 magId "2020106149" @default.
- W2020106149 workType "article" @default.