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• W2020111136 abstract "Pneumococcal polysaccharide vaccine is recommended in western countries for individuals at high risk of pneumococcal illness. We undertook a systematic review of randomised controlled trials of pneumococcal vaccine in adults, to determine the effects on clinical outcomes.In industrialised populations, no benefit was detected for outcomes other than pneumococcal bacteraemia, and this did not reach statistical significance. In non-industrial populations, clear benefit was demonstrated for mortality and all-cause pneumonia.Benefit from pneumococcal vaccination depends on the baseline risk of infection and characteristics of a given population. Evidence from randomised trials for widespread adult vaccination in industrial countries is lacking." @default.
• W2020111136 created "2016-06-24" @default.
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• W2020111136 date "2002-05-01" @default.
• W2020111136 modified "2023-09-25" @default.
• W2020111136 title "Pneumococcal polysaccharide vaccine: a systematic review of clinical effectiveness in adults" @default.
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• W2020111136 doi "https://doi.org/10.1016/s0264-410x(02)00112-3" @default.
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