FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020112528> ?p ?o ?g. }

• W2020112528 endingPage "240" @default.
• W2020112528 startingPage "224" @default.
• W2020112528 abstract "Cell death contributes to the maintenance of homeostasis, but mounting evidence has confirmed the involvement of programmed cell death in some diseases. The concept of programmed cell death, which was coined several decades ago to refer to apoptosis, now also encompasses necroptosis, a newly characterized cell death program. Research on programmed cell death has become essential for the development of some new therapies. To study cell death signaling and its molecular mechanisms, new biochemical and fluorogenic approaches have been devised. Here, we first provide an overview of programmed cell death modes and the importance of dynamic cell death studies. Next, we focus on both apoptotic and necroptotic signaling and their mechanisms by providing a systematic review of all the methods and approaches that have been used. We emphasize the contribution of advanced approaches based on fluorescent probes, reporters, and Förster resonance energy transfer (FRET)-based biosensors for studying programmed cell death. Because apoptosis and necroptosis signaling pathways share some effectors molecules, we discuss how these new tools could be used to discriminate between apoptosis and necroptosis. We also describe how we developed specific FRET-based biosensors for detecting necroptosis. Finally, we touch on how dynamic measurement of biomolecules in living models will play a role in personalized prognosis and therapy." @default.
• W2020112528 created "2016-06-24" @default.
• W2020112528 creator A5018292867 @default.
• W2020112528 creator A5025457629 @default.
• W2020112528 creator A5035748564 @default.
• W2020112528 creator A5089113838 @default.
• W2020112528 date "2014-01-03" @default.
• W2020112528 modified "2023-10-18" @default.
• W2020112528 title "Shining light on cell death processes - a novel biosensor for necroptosis, a newly described cell death program" @default.
• W2020112528 cites W1490928153 @default.
• W2020112528 cites W1507812324 @default.
• W2020112528 cites W1521411817 @default.
• W2020112528 cites W152275004 @default.
• W2020112528 cites W1535426243 @default.
• W2020112528 cites W1540852592 @default.
• W2020112528 cites W1832527043 @default.
• W2020112528 cites W1885181558 @default.
• W2020112528 cites W1896741986 @default.
• W2020112528 cites W1940692702 @default.
• W2020112528 cites W1964083798 @default.
• W2020112528 cites W1964140720 @default.
• W2020112528 cites W1965555958 @default.
• W2020112528 cites W1967139573 @default.
• W2020112528 cites W1970101659 @default.
• W2020112528 cites W1971778847 @default.
• W2020112528 cites W1971891393 @default.
• W2020112528 cites W1972392850 @default.
• W2020112528 cites W1973059552 @default.
• W2020112528 cites W1975593978 @default.
• W2020112528 cites W1975667190 @default.
• W2020112528 cites W1976141746 @default.
• W2020112528 cites W1976647852 @default.
• W2020112528 cites W1976720365 @default.
• W2020112528 cites W1976881265 @default.
• W2020112528 cites W1979032223 @default.
• W2020112528 cites W1979107490 @default.
• W2020112528 cites W1980800538 @default.
• W2020112528 cites W1983568583 @default.
• W2020112528 cites W1986790770 @default.
• W2020112528 cites W1987213099 @default.
• W2020112528 cites W1987527151 @default.
• W2020112528 cites W1988860478 @default.
• W2020112528 cites W1990328562 @default.
• W2020112528 cites W1991429659 @default.
• W2020112528 cites W1995375772 @default.
• W2020112528 cites W1995747121 @default.
• W2020112528 cites W1996177324 @default.
• W2020112528 cites W1997183854 @default.
• W2020112528 cites W1997708855 @default.
• W2020112528 cites W1997731814 @default.
• W2020112528 cites W1997794863 @default.
• W2020112528 cites W1998665747 @default.
• W2020112528 cites W2003935158 @default.
• W2020112528 cites W2004266769 @default.
• W2020112528 cites W2005138952 @default.
• W2020112528 cites W2005203135 @default.
• W2020112528 cites W2007517675 @default.
• W2020112528 cites W2008596036 @default.
• W2020112528 cites W2008757142 @default.
• W2020112528 cites W2010761126 @default.
• W2020112528 cites W2012141576 @default.
• W2020112528 cites W2012985988 @default.
• W2020112528 cites W2014632136 @default.
• W2020112528 cites W2015065783 @default.
• W2020112528 cites W2018382183 @default.
• W2020112528 cites W2019158957 @default.
• W2020112528 cites W2019988435 @default.
• W2020112528 cites W2020858662 @default.
• W2020112528 cites W2020882829 @default.
• W2020112528 cites W2020987391 @default.
• W2020112528 cites W2022015605 @default.
• W2020112528 cites W2022054103 @default.
• W2020112528 cites W2022195980 @default.
• W2020112528 cites W2022366951 @default.
• W2020112528 cites W2026873116 @default.
• W2020112528 cites W2027631918 @default.
• W2020112528 cites W2031552343 @default.
• W2020112528 cites W2031727967 @default.
• W2020112528 cites W2033914606 @default.
• W2020112528 cites W2033968700 @default.
• W2020112528 cites W2034269086 @default.
• W2020112528 cites W2035449163 @default.
• W2020112528 cites W2036186447 @default.
• W2020112528 cites W2036457027 @default.
• W2020112528 cites W2037679360 @default.
• W2020112528 cites W2037805669 @default.
• W2020112528 cites W2038401000 @default.
• W2020112528 cites W2038679462 @default.
• W2020112528 cites W2038884068 @default.
• W2020112528 cites W2040810776 @default.
• W2020112528 cites W2042141743 @default.
• W2020112528 cites W2042506368 @default.
• W2020112528 cites W2042577315 @default.
• W2020112528 cites W2042901183 @default.
• W2020112528 cites W2043472746 @default.
• W2020112528 cites W2044677972 @default.
• W2020112528 cites W2045949658 @default.
• W2020112528 cites W2049001563 @default.

• next