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• W2020113666 endingPage "231" @default.
• W2020113666 startingPage "222" @default.
• W2020113666 abstract "The sterol and phospholipid composition of cercariae, schistosomula, and adult Schistosoma mansoni was analyzed by gas-liquid chromatography and high-performance liquid chromatography (HPLC). Cercariae and schistosomula contained cholesterol, desmosterol, campesterol, stigmasterol, and β-sitosterol while adults contained only cholesterol. In all stages cholesterol comprised greater than 50% of the total sterols, and in cercariae and schistosomula desmosterol comprised 38 and 21% of the total sterols, respectively. The other three sterols, campesterol, stigmasterol, and β-sitosterol, made up approximately 10% of the total. The same five sterols found in cercariae and schistosomula were present in the hepatopancreas of uninfected snails but with a much higher desmosterol concentration in the parasite, 38%, than in the snail, 2%. As in cercariae and schistosomula the three minor sterols comprised approximately 10%. Thus, the sterol composition of cercariae and schistosomula was similar but not identical to that of the snail host. Phosphatidylcholine was the major phospholipid of all three stages (50%) as determined by two HPLC procedures. The remaining phospholipids consisted of phosphatidylethanolamine, phosphatidylserine, and phosphatidylinositol. In addition, in adults there were small quantities of sphingomyelin and lysophosphatidylcholine. The percentage of each phospholipid was similar among stages with the exception of a slight increase in phosphatidylserine in adults compared to cercariae and schistosomula. These results show that a characteristic lipid composition is found in cercariae, schistosomula, and adults." @default.
• W2020113666 created "2016-06-24" @default.
• W2020113666 creator A5014618971 @default.
• W2020113666 creator A5043746115 @default.
• W2020113666 date "1988-04-01" @default.
• W2020113666 modified "2023-09-29" @default.
• W2020113666 title "Schistosoma mansoni: Sterol and phospholipid composition of cercariae, schistosomula, and adults" @default.
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• W2020113666 doi "https://doi.org/10.1016/0014-4894(88)90126-9" @default.
• W2020113666 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3350102" @default.
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