Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020116618> ?p ?o ?g. }
- W2020116618 abstract "Striatal-enriched protein tyrosine phosphatase (STEP) has recently been implicated in several neuropsychiatric disorders with significant cognitive impairments, including Alzheimer's disease, schizophrenia, and fragile X syndrome. A model has emerged by which STEP normally opposes the development of synaptic strengthening and that disruption in STEP activity leads to aberrant synaptic function. We review the mechanisms by which STEP contributes to the etiology of these and other neuropsychiatric disorders. These findings suggest that disruptions in STEP activity may be a common mechanism for cognitive impairments in diverse illnesses." @default.
- W2020116618 created "2016-06-24" @default.
- W2020116618 creator A5080915093 @default.
- W2020116618 creator A5082203779 @default.
- W2020116618 date "2011-01-01" @default.
- W2020116618 modified "2023-09-29" @default.
- W2020116618 title "The Role of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) in Cognition" @default.
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