FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020117622> ?p ?o ?g. }

• W2020117622 endingPage "594" @default.
• W2020117622 startingPage "588" @default.
• W2020117622 abstract "A conceptually novel approach to the design of reactivators of nerve agent-inhibited acetylcholinesterase (AChE) is presented. The concept comprises the linkage of a peripheral site ligand via a spacer to a reactivating moiety with the eventual goal to develop non-ionic reactivators with sufficient affinity for AChE to induce reactivation and potentially improved blood–brain barrier penetration. Herein, the first step towards that goal—the synthesis and biological evaluation of a peripheral site ligand conjugated to a charged pyridinium oxime is discussed. It was found, that the introduction of the peripheral site ligand not only increased affinity of the construct for AChE but also enhanced reactivation of nerve agent-inhibited AChE." @default.
• W2020117622 created "2016-06-24" @default.
• W2020117622 creator A5015573185 @default.
• W2020117622 creator A5044394854 @default.
• W2020117622 creator A5062557643 @default.
• W2020117622 creator A5066436854 @default.
• W2020117622 creator A5085703317 @default.
• W2020117622 date "2011-01-01" @default.
• W2020117622 modified "2023-09-27" @default.
• W2020117622 title "Peripheral site ligand–oxime conjugates: A novel concept towards reactivation of nerve agent-inhibited human acetylcholinesterase" @default.
• W2020117622 cites W1589964883 @default.
• W2020117622 cites W1967451867 @default.
• W2020117622 cites W1969690495 @default.
• W2020117622 cites W1971048984 @default.
• W2020117622 cites W1990583466 @default.
• W2020117622 cites W1992904112 @default.
• W2020117622 cites W1994597200 @default.
• W2020117622 cites W2008742048 @default.
• W2020117622 cites W2011779746 @default.
• W2020117622 cites W2013132270 @default.
• W2020117622 cites W2017398057 @default.
• W2020117622 cites W2019191056 @default.
• W2020117622 cites W2025046505 @default.
• W2020117622 cites W2025815765 @default.
• W2020117622 cites W2030203690 @default.
• W2020117622 cites W2041706446 @default.
• W2020117622 cites W2048581466 @default.
• W2020117622 cites W2059750673 @default.
• W2020117622 cites W2065756285 @default.
• W2020117622 cites W2066122883 @default.
• W2020117622 cites W2080254229 @default.
• W2020117622 cites W2085958374 @default.
• W2020117622 cites W2086174930 @default.
• W2020117622 cites W2086876960 @default.
• W2020117622 cites W2089531787 @default.
• W2020117622 cites W2089909716 @default.
• W2020117622 cites W2090249413 @default.
• W2020117622 cites W2094819493 @default.
• W2020117622 cites W2114102865 @default.
• W2020117622 cites W2115475052 @default.
• W2020117622 cites W2142565832 @default.
• W2020117622 cites W2146910635 @default.
• W2020117622 cites W2319571623 @default.
• W2020117622 cites W4211173363 @default.
• W2020117622 doi "https://doi.org/10.1016/j.bmc.2010.10.059" @default.
• W2020117622 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21112787" @default.
• W2020117622 hasPublicationYear "2011" @default.
• W2020117622 type Work @default.
• W2020117622 sameAs 2020117622 @default.
• W2020117622 citedByCount "36" @default.
• W2020117622 countsByYear W20201176222012 @default.
• W2020117622 countsByYear W20201176222013 @default.
• W2020117622 countsByYear W20201176222014 @default.
• W2020117622 countsByYear W20201176222015 @default.
• W2020117622 countsByYear W20201176222016 @default.
• W2020117622 countsByYear W20201176222017 @default.
• W2020117622 countsByYear W20201176222018 @default.
• W2020117622 countsByYear W20201176222019 @default.
• W2020117622 countsByYear W20201176222020 @default.
• W2020117622 countsByYear W20201176222021 @default.
• W2020117622 countsByYear W20201176222022 @default.
• W2020117622 countsByYear W20201176222023 @default.
• W2020117622 crossrefType "journal-article" @default.
• W2020117622 hasAuthorship W2020117622A5015573185 @default.
• W2020117622 hasAuthorship W2020117622A5044394854 @default.
• W2020117622 hasAuthorship W2020117622A5062557643 @default.
• W2020117622 hasAuthorship W2020117622A5066436854 @default.
• W2020117622 hasAuthorship W2020117622A5085703317 @default.
• W2020117622 hasConcept C116569031 @default.
• W2020117622 hasConcept C134306372 @default.
• W2020117622 hasConcept C170493617 @default.
• W2020117622 hasConcept C181199279 @default.
• W2020117622 hasConcept C185592680 @default.
• W2020117622 hasConcept C197336794 @default.
• W2020117622 hasConcept C21951064 @default.
• W2020117622 hasConcept C2776568683 @default.
• W2020117622 hasConcept C2778706303 @default.
• W2020117622 hasConcept C2778816929 @default.
• W2020117622 hasConcept C2779648554 @default.
• W2020117622 hasConcept C33923547 @default.
• W2020117622 hasConcept C41183919 @default.
• W2020117622 hasConcept C55493867 @default.
• W2020117622 hasConcept C71240020 @default.
• W2020117622 hasConceptScore W2020117622C116569031 @default.
• W2020117622 hasConceptScore W2020117622C134306372 @default.
• W2020117622 hasConceptScore W2020117622C170493617 @default.
• W2020117622 hasConceptScore W2020117622C181199279 @default.
• W2020117622 hasConceptScore W2020117622C185592680 @default.
• W2020117622 hasConceptScore W2020117622C197336794 @default.
• W2020117622 hasConceptScore W2020117622C21951064 @default.
• W2020117622 hasConceptScore W2020117622C2776568683 @default.
• W2020117622 hasConceptScore W2020117622C2778706303 @default.
• W2020117622 hasConceptScore W2020117622C2778816929 @default.
• W2020117622 hasConceptScore W2020117622C2779648554 @default.
• W2020117622 hasConceptScore W2020117622C33923547 @default.
• W2020117622 hasConceptScore W2020117622C41183919 @default.
• W2020117622 hasConceptScore W2020117622C55493867 @default.
• W2020117622 hasConceptScore W2020117622C71240020 @default.

• next