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- W2020117730 endingPage "616" @default.
- W2020117730 startingPage "612" @default.
- W2020117730 abstract "In response to endotoxin, macrophages secrete a protein with a molecular mass of approximately 6000 Da and with an affinity for heparin. This protein, which we term macrophage inflammatory protein 2, is a potent chemotactic agent for human polymorphonuclear leukocytes. In addition, subcutaneous administration of the monokine causes a localized inflammatory reaction. Partial N-terminal sequence data reveal similarity to a family of proteins, the archetype of which is platelet factor 4. Although macrophage inflammatory protein 2 is a distinct member of the platelet factor 4 family, its sequence is most closely related to that of the gro/KC gene product, which is expressed in transformed or platelet-derived growth factor-treated cells." @default.
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- W2020117730 date "1989-01-01" @default.
- W2020117730 modified "2023-09-27" @default.
- W2020117730 title "Identification and characterization of macrophage inflammatory protein 2." @default.
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- W2020117730 doi "https://doi.org/10.1073/pnas.86.2.612" @default.
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