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• W2020119586 abstract "The authors assess the effect of surgical margin width on recurrence rates after intestinal resection of Crohn's Disease (CD).The optimal width of margins when resecting DC of the small bowel is controversial. Most studies have been retrospective and have had conflicting results.Patients undergoing ileocolic resection for CD (N = 152) were randomly assigned to two groups in which the proximal line of resection was 2 cm (limited resection) or 12 cm (extended resection) from the macroscopically involved area. Patients also were classified by whether the margin of resection was microscopically normal (category 1), contained nonspecific changes (category 2), were suggestive but not diagnostic for CD (category 3), or were diagnostic for CD (category 4). Recurrence was defined as reoperation for recurrent preanastomotic disease.Data were collected on 131 patients. Median follow-up time was 55.7 months. Disease recurred in 29 patients: 25% of patients in the limited resection group and 18% of patients in the extended resection group. In the 90 patients in category 1 with normal tissue, recurrence occurred in 16, whereas in the 41 patients with some degree of microscopic involvement, recurrence occurred in 13. Recurrence rates were 36% in category 2, 39% in category 3, and 21% in category 4. No group differences were statistically at the 0.01 level.Recurrence of CD is unaffected by the width of the margin of resection from macroscopically involved bowel. Recurrence rates also do not increase when microscopic CD is present at the resection margins. Therefore, extensive resection margins are unnecessary." @default.
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• W2020119586 date "1996-10-01" @default.
• W2020119586 modified "2023-10-13" @default.
• W2020119586 title "Effect of Resection Margins on the Recurrence of Crohn's Disease in the Small Bowel" @default.
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• W2020119586 doi "https://doi.org/10.1097/00000658-199610000-00014" @default.
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