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• W2020122212 abstract "Multidrug transporters are of considerable importance because they present problems in the treatment of infectious disease and cancer. A central issue is the ability of efflux pumps to recognize an astounding array of structurally diverse compounds. The yeast Pdr5p efflux pump, which is a member of the ATP-binding cassette superfamily, has at least 3 substrate-binding sites, each of which appears to use different chemical properties to transport compounds. All Pdr5p substrates, however, have a size requirement that is independent of hydrophobicity." @default.
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• W2020122212 date "2007-04-01" @default.
• W2020122212 modified "2023-10-18" @default.
• W2020122212 title "The yeast Pdr5p multidrug transporter: How does it recognize so many substrates?" @default.
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• W2020122212 doi "https://doi.org/10.1016/j.bbrc.2007.02.011" @default.
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