FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020122235> ?p ?o ?g. }

• W2020122235 endingPage "773" @default.
• W2020122235 startingPage "766" @default.
• W2020122235 abstract "Introduction The one-step nucleic acid amplification (OSNA) is a molecular procedure that yields a semiquantitative result for detection of nodal metastasis. Size of metastasis in the sentinel lymph node (SLN) by conventional histology has been described as a predictive factor for additional axillary metastasis. The objective of this study is to quantify intraoperatively the total tumoral load (TTL) in the positive SLNs assessed by OSNA and to determine whether this TTL predicts non-SLN metastasis in patients with clinically node negative early stage breast cancer. Methods 306 patients with cT1-3N0 invasive breast cancer who had undergone intraoperative SLN evaluation by OSNA were included. TTL was defined as the addition of CK19 mRNA copies of each positive SLN (copies/μL). Results TTL was a predictive factor of additional non-SLN metastasis in the complete axillary lymph node dissection (cALND) (OR, 1.67; 95% CI, 1.18–2.35). In the multivariate analysis, the TTL was a predictor of non-SLN metastasis in HR positive patients (OR, 1.69; 95% CI, 1.19–2.41). In our cohort of patients, with a TTL ≤1.2 × 105 copies/μL, there was a specificity of 85.3% and negative predictive value (NPV) of 80%. If we consider only the HR positive patients, with a TTL ≤5 × 105 copies/μL there was a specificity of 86.7% and NPV of 83.7%. Conclusions TTL assessed by OSNA assay predicts for additional non-SLN metastasis and this intraoperative tool can help guiding decisions on performing a cALND in breast cancer patients." @default.
• W2020122235 created "2016-06-24" @default.
• W2020122235 creator A5006623826 @default.
• W2020122235 creator A5017466693 @default.
• W2020122235 creator A5036020728 @default.
• W2020122235 creator A5037023029 @default.
• W2020122235 creator A5052985051 @default.
• W2020122235 creator A5061073254 @default.
• W2020122235 creator A5069488075 @default.
• W2020122235 creator A5074774723 @default.
• W2020122235 date "2013-07-01" @default.
• W2020122235 modified "2023-10-09" @default.
• W2020122235 title "Prediction of non-sentinel lymph node metastasis in early breast cancer by assessing total tumoral load in the sentinel lymph node by molecular assay" @default.
• W2020122235 cites W1487259648 @default.
• W2020122235 cites W1536612678 @default.
• W2020122235 cites W1574811228 @default.
• W2020122235 cites W1997427291 @default.
• W2020122235 cites W2006749087 @default.
• W2020122235 cites W2007686878 @default.
• W2020122235 cites W2009191617 @default.
• W2020122235 cites W2024178407 @default.
• W2020122235 cites W2029738263 @default.
• W2020122235 cites W2035639435 @default.
• W2020122235 cites W2044817415 @default.
• W2020122235 cites W2045420532 @default.
• W2020122235 cites W2047289426 @default.
• W2020122235 cites W2054884958 @default.
• W2020122235 cites W2074657677 @default.
• W2020122235 cites W2083004296 @default.
• W2020122235 cites W2086451007 @default.
• W2020122235 cites W2089140194 @default.
• W2020122235 cites W2095471137 @default.
• W2020122235 cites W2096785769 @default.
• W2020122235 cites W2097255042 @default.
• W2020122235 cites W2097746568 @default.
• W2020122235 cites W2103312160 @default.
• W2020122235 cites W2105416121 @default.
• W2020122235 cites W2112516937 @default.
• W2020122235 cites W2115825530 @default.
• W2020122235 cites W2131476017 @default.
• W2020122235 cites W2132522727 @default.
• W2020122235 cites W2133264822 @default.
• W2020122235 cites W2146745078 @default.
• W2020122235 cites W2150134401 @default.
• W2020122235 cites W2156353983 @default.
• W2020122235 cites W2163679054 @default.
• W2020122235 cites W4234081105 @default.
• W2020122235 doi "https://doi.org/10.1016/j.ejso.2013.03.011" @default.
• W2020122235 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23607911" @default.
• W2020122235 hasPublicationYear "2013" @default.
• W2020122235 type Work @default.
• W2020122235 sameAs 2020122235 @default.
• W2020122235 citedByCount "51" @default.
• W2020122235 countsByYear W20201222352013 @default.
• W2020122235 countsByYear W20201222352014 @default.
• W2020122235 countsByYear W20201222352015 @default.
• W2020122235 countsByYear W20201222352016 @default.
• W2020122235 countsByYear W20201222352017 @default.
• W2020122235 countsByYear W20201222352018 @default.
• W2020122235 countsByYear W20201222352019 @default.
• W2020122235 countsByYear W20201222352020 @default.
• W2020122235 countsByYear W20201222352021 @default.
• W2020122235 countsByYear W20201222352022 @default.
• W2020122235 countsByYear W20201222352023 @default.
• W2020122235 crossrefType "journal-article" @default.
• W2020122235 hasAuthorship W2020122235A5006623826 @default.
• W2020122235 hasAuthorship W2020122235A5017466693 @default.
• W2020122235 hasAuthorship W2020122235A5036020728 @default.
• W2020122235 hasAuthorship W2020122235A5037023029 @default.
• W2020122235 hasAuthorship W2020122235A5052985051 @default.
• W2020122235 hasAuthorship W2020122235A5061073254 @default.
• W2020122235 hasAuthorship W2020122235A5069488075 @default.
• W2020122235 hasAuthorship W2020122235A5074774723 @default.
• W2020122235 hasConcept C121608353 @default.
• W2020122235 hasConcept C126322002 @default.
• W2020122235 hasConcept C143998085 @default.
• W2020122235 hasConcept C146357865 @default.
• W2020122235 hasConcept C151730666 @default.
• W2020122235 hasConcept C2778123414 @default.
• W2020122235 hasConcept C2779013556 @default.
• W2020122235 hasConcept C2780212769 @default.
• W2020122235 hasConcept C2908949552 @default.
• W2020122235 hasConcept C530470458 @default.
• W2020122235 hasConcept C71924100 @default.
• W2020122235 hasConcept C86803240 @default.
• W2020122235 hasConceptScore W2020122235C121608353 @default.
• W2020122235 hasConceptScore W2020122235C126322002 @default.
• W2020122235 hasConceptScore W2020122235C143998085 @default.
• W2020122235 hasConceptScore W2020122235C146357865 @default.
• W2020122235 hasConceptScore W2020122235C151730666 @default.
• W2020122235 hasConceptScore W2020122235C2778123414 @default.
• W2020122235 hasConceptScore W2020122235C2779013556 @default.
• W2020122235 hasConceptScore W2020122235C2780212769 @default.
• W2020122235 hasConceptScore W2020122235C2908949552 @default.
• W2020122235 hasConceptScore W2020122235C530470458 @default.
• W2020122235 hasConceptScore W2020122235C71924100 @default.
• W2020122235 hasConceptScore W2020122235C86803240 @default.
• W2020122235 hasIssue "7" @default.

• next