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- W2020130274 abstract "To the Editor: We read with interest the recent article by Naguib et al. (1) in which they investigated different doses of succinylcholine for rapid-sequence induction of anesthesia. We agree with these authors that a dose of succinylcholine higher than 1.5 mg/kg is not necessary for tracheal intubation. A high dose of succinylcholine (2–5 mg/kg) may result in so-called “Phase II block,” in which the characteristics of neuromuscular blockade resemble those of the nondepolarizing drugs, and the duration of blockade is considerably prolonged (2). We also oppose the use of small-dose succinylcholine (<1.0 mg/kg) to facilitate intubation, although 0.5 mg/kg succinylcholine has been considered as an acceptable dose (3). In some unpredicted difficult situations, the incidence of failure may be increased with a small dose of succinylcholine (4). In our opinion, 1.0–1.5 mg/kg succinylcholine is the ideal dose for intubation in clinical anesthesia. Zhijun Lu, MD Ying Wang, MD Buwei Yu, MD Department of Anesthesiology Rui Jin Hospital Shanghai Jiao Tong University School of Medicine Shanghai, People’s Republic of China [email protected]" @default.
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- W2020130274 date "2006-12-01" @default.
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- W2020130274 title "The Ideal Dose of Succinylcholine for Tracheal Intubation" @default.
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- W2020130274 doi "https://doi.org/10.1213/01.ane.0000246431.57502.56" @default.
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