FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020137628> ?p ?o ?g. }

• W2020137628 endingPage "2030" @default.
• W2020137628 startingPage "2025" @default.
• W2020137628 abstract "Empirical broad-spectrum antibiotic treatment for orthopaedic implant infections after surgical lavage is common practice while awaiting microbiological results, but lacks evidence. This was a single-centre cohort study from 1996 to 2010 with a follow-up of two years. We retrieved 342 implant infections and followed them up for a median of 3.5 years (61 recurred, 18 %). Infected implants were arthroplasties (n = 186), different plates, nails or other osteosyntheses. The main pathogens were S. aureus (163, 49 methicillin-resistant) and coagulase-negative staphylococci (60, 45 methicillin-resistant). Median duration of empirical antibiotic coverage after surgical drainage was three days before switching to targeted therapy. Vancomycin was the most frequent initial empirical agent (147), followed by intravenous co-amoxiclav (44). Most empirical antibiotic regimens (269, 79 %) proved sensitive to the causative pathogen, but were too broad in 111 episodes (32 %). Cephalosporins and penicillins were used only in 44 and ten cases, respectively, although they would have covered 59 % of causative pathogens identified later. Multivariate Cox regression analysis showed that neither susceptible antibiotic coverage (compared to non-susceptible; hazard ratio 0.7, 95 % confidence interval 0.4–1.2) nor broad-spectrum use (hazard ratio 1.1, 0.8–1.5) changed remission rates. Provided that surgical drainage is performed, broad-spectrum antibiotic coverage does not enhance remission of orthopaedic implant infections during the first three days. If empirical agents are prescribed from the first day of infection, narrow-spectrum penicillins or cephalosporins can be considered to avoid unnecessary broad-spectrum antibiotic use." @default.
• W2020137628 created "2016-06-24" @default.
• W2020137628 creator A5024496341 @default.
• W2020137628 creator A5027889227 @default.
• W2020137628 creator A5032197925 @default.
• W2020137628 creator A5033081374 @default.
• W2020137628 creator A5049353553 @default.
• W2020137628 creator A5051798113 @default.
• W2020137628 creator A5053821527 @default.
• W2020137628 creator A5084968400 @default.
• W2020137628 creator A5089591096 @default.
• W2020137628 date "2013-06-07" @default.
• W2020137628 modified "2023-10-04" @default.
• W2020137628 title "No need for broad-spectrum empirical antibiotic coverage after surgical drainage of orthopaedic implant infections" @default.
• W2020137628 cites W1983255179 @default.
• W2020137628 cites W2001420273 @default.
• W2020137628 cites W2005303662 @default.
• W2020137628 cites W2010925338 @default.
• W2020137628 cites W2016579435 @default.
• W2020137628 cites W2030950429 @default.
• W2020137628 cites W2045892056 @default.
• W2020137628 cites W2069969451 @default.
• W2020137628 cites W2088293790 @default.
• W2020137628 cites W2090401570 @default.
• W2020137628 cites W2102037222 @default.
• W2020137628 cites W2130373985 @default.
• W2020137628 cites W2150019069 @default.
• W2020137628 cites W2170769378 @default.
• W2020137628 cites W4255058194 @default.
• W2020137628 cites W4366327009 @default.
• W2020137628 doi "https://doi.org/10.1007/s00264-013-1924-3" @default.
• W2020137628 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3779563" @default.
• W2020137628 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23744500" @default.
• W2020137628 hasPublicationYear "2013" @default.
• W2020137628 type Work @default.
• W2020137628 sameAs 2020137628 @default.
• W2020137628 citedByCount "9" @default.
• W2020137628 countsByYear W20201376282019 @default.
• W2020137628 countsByYear W20201376282020 @default.
• W2020137628 countsByYear W20201376282021 @default.
• W2020137628 countsByYear W20201376282022 @default.
• W2020137628 countsByYear W20201376282023 @default.
• W2020137628 crossrefType "journal-article" @default.
• W2020137628 hasAuthorship W2020137628A5024496341 @default.
• W2020137628 hasAuthorship W2020137628A5027889227 @default.
• W2020137628 hasAuthorship W2020137628A5032197925 @default.
• W2020137628 hasAuthorship W2020137628A5033081374 @default.
• W2020137628 hasAuthorship W2020137628A5049353553 @default.
• W2020137628 hasAuthorship W2020137628A5051798113 @default.
• W2020137628 hasAuthorship W2020137628A5053821527 @default.
• W2020137628 hasAuthorship W2020137628A5084968400 @default.
• W2020137628 hasAuthorship W2020137628A5089591096 @default.
• W2020137628 hasBestOaLocation W20201376282 @default.
• W2020137628 hasConcept C126322002 @default.
• W2020137628 hasConcept C141071460 @default.
• W2020137628 hasConcept C207103383 @default.
• W2020137628 hasConcept C2776968632 @default.
• W2020137628 hasConcept C2777637488 @default.
• W2020137628 hasConcept C2778980435 @default.
• W2020137628 hasConcept C2779489039 @default.
• W2020137628 hasConcept C2781411149 @default.
• W2020137628 hasConcept C44249647 @default.
• W2020137628 hasConcept C501593827 @default.
• W2020137628 hasConcept C523546767 @default.
• W2020137628 hasConcept C54355233 @default.
• W2020137628 hasConcept C64778159 @default.
• W2020137628 hasConcept C68312169 @default.
• W2020137628 hasConcept C71924100 @default.
• W2020137628 hasConcept C86803240 @default.
• W2020137628 hasConcept C89423630 @default.
• W2020137628 hasConceptScore W2020137628C126322002 @default.
• W2020137628 hasConceptScore W2020137628C141071460 @default.
• W2020137628 hasConceptScore W2020137628C207103383 @default.
• W2020137628 hasConceptScore W2020137628C2776968632 @default.
• W2020137628 hasConceptScore W2020137628C2777637488 @default.
• W2020137628 hasConceptScore W2020137628C2778980435 @default.
• W2020137628 hasConceptScore W2020137628C2779489039 @default.
• W2020137628 hasConceptScore W2020137628C2781411149 @default.
• W2020137628 hasConceptScore W2020137628C44249647 @default.
• W2020137628 hasConceptScore W2020137628C501593827 @default.
• W2020137628 hasConceptScore W2020137628C523546767 @default.
• W2020137628 hasConceptScore W2020137628C54355233 @default.
• W2020137628 hasConceptScore W2020137628C64778159 @default.
• W2020137628 hasConceptScore W2020137628C68312169 @default.
• W2020137628 hasConceptScore W2020137628C71924100 @default.
• W2020137628 hasConceptScore W2020137628C86803240 @default.
• W2020137628 hasConceptScore W2020137628C89423630 @default.
• W2020137628 hasIssue "10" @default.
• W2020137628 hasLocation W20201376281 @default.
• W2020137628 hasLocation W20201376282 @default.
• W2020137628 hasLocation W20201376283 @default.
• W2020137628 hasLocation W20201376284 @default.
• W2020137628 hasLocation W20201376285 @default.
• W2020137628 hasOpenAccess W2020137628 @default.
• W2020137628 hasPrimaryLocation W20201376281 @default.
• W2020137628 hasRelatedWork W124277619 @default.
• W2020137628 hasRelatedWork W1555437626 @default.
• W2020137628 hasRelatedWork W2318202707 @default.

• next