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• W2020144991 abstract "This work describes a general method for the synthesis of oligoribonucleotides containing a site-specific nonbridging phosphorodithioate linkage via automated solid-phase synthesis using 5′-O-DMTr-2′-O-TBS-ribonucleoside 3′-N,N-dimethyl-S-(2,4-dichlorobenzyl) phosphorothioamidites (2a–2d). The 3′-phosphorothioamidites (2a–2d) can be conveniently prepared in good yields (86–99%) via a one-pot reaction from the corresponding 5′-O-DMTr-2′-O-TBS-ribonucleosides (1a–1d)." @default.
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• W2020144991 date "2012-10-25" @default.
• W2020144991 modified "2023-10-17" @default.
• W2020144991 title "Automated Solid-Phase Synthesis of RNA Oligonucleotides Containing a Nonbridging Phosphorodithioate Linkage via Phosphorothioamidites" @default.
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• W2020144991 doi "https://doi.org/10.1021/jo301834p" @default.
• W2020144991 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3500914" @default.
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