FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020148382> ?p ?o ?g. }

• W2020148382 endingPage "74" @default.
• W2020148382 startingPage "67" @default.
• W2020148382 abstract "Porphyromonus gingivalis is a major pathogen of chronic periodontitis. An outer membrane protein with a molecular mass of 40-kDa (40k-OMP) is a highly immunogenic surface protein produced by P. gingivalis. In this study, to develop an effective vaccine against P. gingivalis infection, we assessed T helper (Th) cell responses in systemic and mucosal compartments after 40k-OMP was administered transcutaneously. When CD4+ T cells isolated from the spleens of mice immunized with 40k-OMP alone or 40k-OMP plus cholera toxin were restimulated with 40k-OMP in vitro, significant levels of proliferative responses were induced. In contrast, only low levels of CD4+ T cell proliferation were induced in cervical lymph nodes. Analysis of Th1 [interferon (IFN)-γ] and Th2 [interleukin (IL)-4, IL-5, and IL-6] cytokine responses showed that 40k-OMP-specific Th cells from the spleen produced significant levels of IL-4, IL-5, and IL-6 but did not trigger changes in IFN-γ production. These results suggest that transcutaneous administration of 40k-OMP can elicit 40k-OMP-specific Th2-type cytokine responses in systemic, but not mucosal, lymphoid tissues." @default.
• W2020148382 created "2016-06-24" @default.
• W2020148382 creator A5006615953 @default.
• W2020148382 creator A5016129597 @default.
• W2020148382 creator A5020193000 @default.
• W2020148382 creator A5033293938 @default.
• W2020148382 creator A5059626245 @default.
• W2020148382 creator A5078990374 @default.
• W2020148382 date "2004-01-01" @default.
• W2020148382 modified "2023-10-18" @default.
• W2020148382 title "Transcutaneous Immunization with P. gingivalis Surface Protein Antigen Induces T Helper 2 Responses in Systemic Tissues" @default.
• W2020148382 cites W1486323853 @default.
• W2020148382 cites W1549346812 @default.
• W2020148382 cites W1551647859 @default.
• W2020148382 cites W1608119507 @default.
• W2020148382 cites W1625990430 @default.
• W2020148382 cites W1944120618 @default.
• W2020148382 cites W1948574612 @default.
• W2020148382 cites W1975010250 @default.
• W2020148382 cites W1979745641 @default.
• W2020148382 cites W1991035770 @default.
• W2020148382 cites W2013686349 @default.
• W2020148382 cites W2032451916 @default.
• W2020148382 cites W2039751277 @default.
• W2020148382 cites W2042186971 @default.
• W2020148382 cites W2047963768 @default.
• W2020148382 cites W2059742850 @default.
• W2020148382 cites W2069530267 @default.
• W2020148382 cites W2069771231 @default.
• W2020148382 cites W2073766903 @default.
• W2020148382 cites W2074864678 @default.
• W2020148382 cites W2076187086 @default.
• W2020148382 cites W2077313014 @default.
• W2020148382 cites W2083125179 @default.
• W2020148382 cites W2086318374 @default.
• W2020148382 cites W2092593728 @default.
• W2020148382 cites W2101612832 @default.
• W2020148382 cites W2105620704 @default.
• W2020148382 cites W2106761599 @default.
• W2020148382 cites W2108838669 @default.
• W2020148382 cites W2109363224 @default.
• W2020148382 cites W2112990035 @default.
• W2020148382 cites W2122093560 @default.
• W2020148382 cites W2129322668 @default.
• W2020148382 cites W2132665739 @default.
• W2020148382 cites W2136145410 @default.
• W2020148382 cites W2157571961 @default.
• W2020148382 cites W2211987955 @default.
• W2020148382 doi "https://doi.org/10.5466/ijoms.3.67" @default.
• W2020148382 hasPublicationYear "2004" @default.
• W2020148382 type Work @default.
• W2020148382 sameAs 2020148382 @default.
• W2020148382 citedByCount "0" @default.
• W2020148382 crossrefType "journal-article" @default.
• W2020148382 hasAuthorship W2020148382A5006615953 @default.
• W2020148382 hasAuthorship W2020148382A5016129597 @default.
• W2020148382 hasAuthorship W2020148382A5020193000 @default.
• W2020148382 hasAuthorship W2020148382A5033293938 @default.
• W2020148382 hasAuthorship W2020148382A5059626245 @default.
• W2020148382 hasAuthorship W2020148382A5078990374 @default.
• W2020148382 hasBestOaLocation W20201483821 @default.
• W2020148382 hasConcept C142724271 @default.
• W2020148382 hasConcept C147483822 @default.
• W2020148382 hasConcept C203014093 @default.
• W2020148382 hasConcept C2776090121 @default.
• W2020148382 hasConcept C2777006276 @default.
• W2020148382 hasConcept C2778690821 @default.
• W2020148382 hasConcept C2779720271 @default.
• W2020148382 hasConcept C2780801004 @default.
• W2020148382 hasConcept C2780931953 @default.
• W2020148382 hasConcept C2781136212 @default.
• W2020148382 hasConcept C71924100 @default.
• W2020148382 hasConcept C86803240 @default.
• W2020148382 hasConcept C8891405 @default.
• W2020148382 hasConcept C89423630 @default.
• W2020148382 hasConceptScore W2020148382C142724271 @default.
• W2020148382 hasConceptScore W2020148382C147483822 @default.
• W2020148382 hasConceptScore W2020148382C203014093 @default.
• W2020148382 hasConceptScore W2020148382C2776090121 @default.
• W2020148382 hasConceptScore W2020148382C2777006276 @default.
• W2020148382 hasConceptScore W2020148382C2778690821 @default.
• W2020148382 hasConceptScore W2020148382C2779720271 @default.
• W2020148382 hasConceptScore W2020148382C2780801004 @default.
• W2020148382 hasConceptScore W2020148382C2780931953 @default.
• W2020148382 hasConceptScore W2020148382C2781136212 @default.
• W2020148382 hasConceptScore W2020148382C71924100 @default.
• W2020148382 hasConceptScore W2020148382C86803240 @default.
• W2020148382 hasConceptScore W2020148382C8891405 @default.
• W2020148382 hasConceptScore W2020148382C89423630 @default.
• W2020148382 hasIssue "2" @default.
• W2020148382 hasLocation W20201483821 @default.
• W2020148382 hasOpenAccess W2020148382 @default.
• W2020148382 hasPrimaryLocation W20201483821 @default.
• W2020148382 hasRelatedWork W1994735423 @default.
• W2020148382 hasRelatedWork W2006557190 @default.
• W2020148382 hasRelatedWork W2014921289 @default.
• W2020148382 hasRelatedWork W2036107469 @default.
• W2020148382 hasRelatedWork W2081358646 @default.

• next