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• W2020149223 abstract "This paper reports evidence of the very unusual differential cell sensitivity toward compositionally similar surfaces obtained by irradiation treatments. In particular, we studied the adhesion, proliferation, and spreading of normal human dermal fibroblasts onto poly(hydroxymethylsiloxane) surfaces modified by either O2 plasma (aged in air or water) or 6 keV Ar+ beams. The cell response ranges from relatively low adhesion and scarce viability for O2-plasma-treated surfaces to a complete cell confluence and optimal spreading and proliferation in the case of 6-keV Ar+ beams. Two different types of altered layers have been identified for the two irradiation techniques, respectively consisting in an amorphous SiCxOy(Hz) phase, produced in the ion-mixing process in the collision cascades induced by 6-keV Ar+ beams, and an almost pure amorphous SiO2-like phase, produced by the highly selective removal of carbon-containing volatile species in the O2 plasma. The observed differential cell response in the case of various plasma-treated surfaces is related to the relative increase of surface free energy. The peculiar optimal cell response onto Ar+-irradiated surfaces is instead assigned to the peculiar electronic structure and related electrical properties of the ion mixed layer." @default.
• W2020149223 created "2016-06-24" @default.
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• W2020149223 date "2002-10-24" @default.
• W2020149223 modified "2023-10-17" @default.
• W2020149223 title "Differential Cultured Fibroblast Behavior on Plasma and Ion-Beam-Modified Polysiloxane Surfaces" @default.
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• W2020149223 doi "https://doi.org/10.1021/la025800x" @default.
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