FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020149777> ?p ?o ?g. }

• W2020149777 abstract "Abstract Background There is increasing interest in balanced propofol sedation (BPS) titrated to moderate sedation (conscious sedation) for endoscopic procedures. However, few controlled studies on BPS targeted to deep sedation for diagnostic endoscopy were found. Alfentanil, a rapid and short-acting synthetic analog of fentanyl, appears to offer clinically significant advantages over fentanyl during outpatient anesthesia. It is reasonable to hypothesize that low dose of alfentanil used in BPS might also result in more rapid recovery as compared with fentanyl. Methods A prospective, randomized and double-blinded clinical trial of alfentanil, midazolam and propofol versus fentanyl, midazolam and propofol in 272 outpatients undergoing diagnostic esophagogastroduodenal endoscopy (EGD) and colonoscopy for health examination were enrolled. Randomization was achieved by using the computer-generated random sequence. Each combination regimen was titrated to deep sedation. The recovery time, patient satisfaction, safety and the efficacy and cost benefit between groups were compared. Results 260 participants were analyzed, 129 in alfentanil group and 131 in fentanyl group. There is no significant difference in sex, age, body weight, BMI and ASA distribution between two groups. Also, there is no significant difference in recovery time, satisfaction score from patients, propofol consumption, awake time from sedation, and sedation-related cardiopulmonary complications between two groups. Though deep sedation was targeted, all cardiopulmonary complications were minor and transient (10.8%, 28/260). No serious adverse events including the use of flumazenil, assisted ventilation, permanent injury or death, and temporary or permanent interruption of procedure were found in both groups. However, fentanyl is New Taiwan Dollar (NT$) 103 (approximate US$ 4) cheaper than alfentanil, leading to a significant difference in total cost between two groups. Conclusions This randomized, double-blinded clinical trial showed that there is no significant difference in the recovery time, satisfaction score from patients, propofol consumption, awake time from sedation, and sedation-related cardiopulmonary complications between the two most common sedation regimens for EGD and colonoscopy in our hospital. However, fentanyl is NT$103 (US$ 4) cheaper than alfentanil in each case. Trial registration Institutional Review Board of Buddhist Tzu Chi General Hospital (IRB097-18) and Chinese Clinical Trial Registry (ChiCTR-TRC-12002575)" @default.
• W2020149777 created "2016-06-24" @default.
• W2020149777 creator A5005037507 @default.
• W2020149777 creator A5014038449 @default.
• W2020149777 creator A5016966950 @default.
• W2020149777 creator A5020251446 @default.
• W2020149777 creator A5033760418 @default.
• W2020149777 creator A5078150924 @default.
• W2020149777 creator A5082112103 @default.
• W2020149777 date "2012-11-21" @default.
• W2020149777 modified "2023-10-07" @default.
• W2020149777 title "Comparison between the recovery time of alfentanil and fentanyl in balanced propofol sedation for gastrointestinal and colonoscopy: a prospective, randomized study" @default.
• W2020149777 cites W1505637040 @default.
• W2020149777 cites W1927106260 @default.
• W2020149777 cites W1931613497 @default.
• W2020149777 cites W1971010693 @default.
• W2020149777 cites W1976768845 @default.
• W2020149777 cites W1978381685 @default.
• W2020149777 cites W1986576459 @default.
• W2020149777 cites W1989161368 @default.
• W2020149777 cites W1992636390 @default.
• W2020149777 cites W1996435587 @default.
• W2020149777 cites W1998085354 @default.
• W2020149777 cites W2001396063 @default.
• W2020149777 cites W2008921641 @default.
• W2020149777 cites W2035429460 @default.
• W2020149777 cites W2046459582 @default.
• W2020149777 cites W2063120475 @default.
• W2020149777 cites W2069559440 @default.
• W2020149777 cites W2086103904 @default.
• W2020149777 cites W2088243994 @default.
• W2020149777 cites W2101010608 @default.
• W2020149777 cites W2112707619 @default.
• W2020149777 cites W2134806986 @default.
• W2020149777 cites W2144695596 @default.
• W2020149777 cites W2155522117 @default.
• W2020149777 cites W2167489952 @default.
• W2020149777 cites W2324504000 @default.
• W2020149777 cites W2473228235 @default.
• W2020149777 cites W4253096148 @default.
• W2020149777 doi "https://doi.org/10.1186/1471-230x-12-164" @default.
• W2020149777 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3607964" @default.
• W2020149777 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23170921" @default.
• W2020149777 hasPublicationYear "2012" @default.
• W2020149777 type Work @default.
• W2020149777 sameAs 2020149777 @default.
• W2020149777 citedByCount "27" @default.
• W2020149777 countsByYear W20201497772013 @default.
• W2020149777 countsByYear W20201497772014 @default.
• W2020149777 countsByYear W20201497772015 @default.
• W2020149777 countsByYear W20201497772016 @default.
• W2020149777 countsByYear W20201497772017 @default.
• W2020149777 countsByYear W20201497772018 @default.
• W2020149777 countsByYear W20201497772019 @default.
• W2020149777 countsByYear W20201497772020 @default.
• W2020149777 countsByYear W20201497772021 @default.
• W2020149777 countsByYear W20201497772022 @default.
• W2020149777 countsByYear W20201497772023 @default.
• W2020149777 crossrefType "journal-article" @default.
• W2020149777 hasAuthorship W2020149777A5005037507 @default.
• W2020149777 hasAuthorship W2020149777A5014038449 @default.
• W2020149777 hasAuthorship W2020149777A5016966950 @default.
• W2020149777 hasAuthorship W2020149777A5020251446 @default.
• W2020149777 hasAuthorship W2020149777A5033760418 @default.
• W2020149777 hasAuthorship W2020149777A5078150924 @default.
• W2020149777 hasAuthorship W2020149777A5082112103 @default.
• W2020149777 hasBestOaLocation W20201497771 @default.
• W2020149777 hasConcept C121608353 @default.
• W2020149777 hasConcept C126322002 @default.
• W2020149777 hasConcept C141071460 @default.
• W2020149777 hasConcept C168563851 @default.
• W2020149777 hasConcept C2776277131 @default.
• W2020149777 hasConcept C2776814716 @default.
• W2020149777 hasConcept C2778000748 @default.
• W2020149777 hasConcept C2778435480 @default.
• W2020149777 hasConcept C2781072394 @default.
• W2020149777 hasConcept C2781091344 @default.
• W2020149777 hasConcept C42219234 @default.
• W2020149777 hasConcept C526805850 @default.
• W2020149777 hasConcept C71924100 @default.
• W2020149777 hasConceptScore W2020149777C121608353 @default.
• W2020149777 hasConceptScore W2020149777C126322002 @default.
• W2020149777 hasConceptScore W2020149777C141071460 @default.
• W2020149777 hasConceptScore W2020149777C168563851 @default.
• W2020149777 hasConceptScore W2020149777C2776277131 @default.
• W2020149777 hasConceptScore W2020149777C2776814716 @default.
• W2020149777 hasConceptScore W2020149777C2778000748 @default.
• W2020149777 hasConceptScore W2020149777C2778435480 @default.
• W2020149777 hasConceptScore W2020149777C2781072394 @default.
• W2020149777 hasConceptScore W2020149777C2781091344 @default.
• W2020149777 hasConceptScore W2020149777C42219234 @default.
• W2020149777 hasConceptScore W2020149777C526805850 @default.
• W2020149777 hasConceptScore W2020149777C71924100 @default.
• W2020149777 hasIssue "1" @default.
• W2020149777 hasLocation W20201497771 @default.
• W2020149777 hasLocation W20201497772 @default.
• W2020149777 hasLocation W20201497773 @default.
• W2020149777 hasLocation W20201497774 @default.
• W2020149777 hasOpenAccess W2020149777 @default.
• W2020149777 hasPrimaryLocation W20201497771 @default.

• next