Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020154367> ?p ?o ?g. }
- W2020154367 endingPage "431" @default.
- W2020154367 startingPage "423" @default.
- W2020154367 abstract "The revolution in DNA sequencing technologies has now made it feasible to determine the genome sequences of many individuals; i.e., “personal genomes.” Genome sequences of cells and tissues from both normal and disease states have been determined. Using current approaches, whole human genome sequences are not typically assembled and determined de novo, but, instead, variations relative to a reference sequence are identified. We discuss the current state of personal genome sequencing, the main steps involved in determining a genome sequence (i.e., identifying single-nucleotide polymorphisms [SNPs] and structural variations [SVs], assembling new sequences, and phasing haplotypes), and the challenges and performance metrics for evaluating the accuracy of the reconstruction. Finally, we consider the possible individual and societal benefits of personal genome sequences." @default.
- W2020154367 created "2016-06-24" @default.
- W2020154367 creator A5033955453 @default.
- W2020154367 creator A5042321575 @default.
- W2020154367 creator A5058814917 @default.
- W2020154367 date "2010-03-01" @default.
- W2020154367 modified "2023-10-12" @default.
- W2020154367 title "Personal genome sequencing: current approaches and challenges" @default.
- W2020154367 cites W1484187172 @default.
- W2020154367 cites W1699155395 @default.
- W2020154367 cites W1841715584 @default.
- W2020154367 cites W1856707437 @default.
- W2020154367 cites W1972341995 @default.
- W2020154367 cites W1973950074 @default.
- W2020154367 cites W1988442083 @default.
- W2020154367 cites W1994458586 @default.
- W2020154367 cites W2001725958 @default.
- W2020154367 cites W2006782785 @default.
- W2020154367 cites W2012016911 @default.
- W2020154367 cites W2021714239 @default.
- W2020154367 cites W2024975965 @default.
- W2020154367 cites W2030692069 @default.
- W2020154367 cites W2032247293 @default.
- W2020154367 cites W2043186892 @default.
- W2020154367 cites W2048986223 @default.
- W2020154367 cites W2065817684 @default.
- W2020154367 cites W2099855466 @default.
- W2020154367 cites W2112113834 @default.
- W2020154367 cites W2112515280 @default.
- W2020154367 cites W2113649367 @default.
- W2020154367 cites W2124960286 @default.
- W2020154367 cites W2124985265 @default.
- W2020154367 cites W2125572577 @default.
- W2020154367 cites W2129326667 @default.
- W2020154367 cites W2134061682 @default.
- W2020154367 cites W2136651963 @default.
- W2020154367 cites W2137779717 @default.
- W2020154367 cites W2138603354 @default.
- W2020154367 cites W2139216037 @default.
- W2020154367 cites W2140869203 @default.
- W2020154367 cites W2140911647 @default.
- W2020154367 cites W2142642738 @default.
- W2020154367 cites W2142749416 @default.
- W2020154367 cites W2143196035 @default.
- W2020154367 cites W2148088841 @default.
- W2020154367 cites W2150677022 @default.
- W2020154367 cites W2152559981 @default.
- W2020154367 cites W2153010521 @default.
- W2020154367 cites W2159946869 @default.
- W2020154367 cites W2160825263 @default.
- W2020154367 cites W2162048779 @default.
- W2020154367 cites W2168909179 @default.
- W2020154367 cites W2169508919 @default.
- W2020154367 cites W2217809488 @default.
- W2020154367 doi "https://doi.org/10.1101/gad.1864110" @default.
- W2020154367 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2827837" @default.
- W2020154367 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20194435" @default.
- W2020154367 hasPublicationYear "2010" @default.
- W2020154367 type Work @default.
- W2020154367 sameAs 2020154367 @default.
- W2020154367 citedByCount "123" @default.
- W2020154367 countsByYear W20201543672012 @default.
- W2020154367 countsByYear W20201543672013 @default.
- W2020154367 countsByYear W20201543672014 @default.
- W2020154367 countsByYear W20201543672015 @default.
- W2020154367 countsByYear W20201543672016 @default.
- W2020154367 countsByYear W20201543672017 @default.
- W2020154367 countsByYear W20201543672018 @default.
- W2020154367 countsByYear W20201543672019 @default.
- W2020154367 countsByYear W20201543672020 @default.
- W2020154367 countsByYear W20201543672021 @default.
- W2020154367 countsByYear W20201543672022 @default.
- W2020154367 countsByYear W20201543672023 @default.
- W2020154367 crossrefType "journal-article" @default.
- W2020154367 hasAuthorship W2020154367A5033955453 @default.
- W2020154367 hasAuthorship W2020154367A5042321575 @default.
- W2020154367 hasAuthorship W2020154367A5058814917 @default.
- W2020154367 hasBestOaLocation W20201543671 @default.
- W2020154367 hasConcept C104317684 @default.
- W2020154367 hasConcept C135763542 @default.
- W2020154367 hasConcept C141231307 @default.
- W2020154367 hasConcept C153209595 @default.
- W2020154367 hasConcept C180754005 @default.
- W2020154367 hasConcept C189206191 @default.
- W2020154367 hasConcept C192953774 @default.
- W2020154367 hasConcept C197077220 @default.
- W2020154367 hasConcept C197754878 @default.
- W2020154367 hasConcept C24103923 @default.
- W2020154367 hasConcept C24432333 @default.
- W2020154367 hasConcept C2778112365 @default.
- W2020154367 hasConcept C51679486 @default.
- W2020154367 hasConcept C54355233 @default.
- W2020154367 hasConcept C70721500 @default.
- W2020154367 hasConcept C86803240 @default.
- W2020154367 hasConcept C89566754 @default.
- W2020154367 hasConceptScore W2020154367C104317684 @default.
- W2020154367 hasConceptScore W2020154367C135763542 @default.
- W2020154367 hasConceptScore W2020154367C141231307 @default.