Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020159512> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2020159512 endingPage "322" @default.
- W2020159512 startingPage "309" @default.
- W2020159512 abstract "A selective, specific and stability-indicating gradient reverse phase highperformance liquid chromatographic (HPLC) method was developed for the determination of Ranitidine in presence of its impurities, forced degradation products and placebo substances such as saccharide and parabens. Ultraviolet detection was performed at 230 nm. Separate portions of the drug product and ingredients were exposed to stress conditions to induce oxidative, acidic, basic, hydrolytic, thermal and photolytic degradation. Ranitidine was found to degrade significantly at acidic, basic and oxidative stress conditions but was stable at heat and humidity. The developed method was validated as per International Conference on Harmonization (ICH) guidelines. The method was validated over this range for (i) system suitability (ii) specificity, (iii) precision, (iv) limit of detection and limit of quantification, (v) linearity, (vi) accuracy, (vii) robustness. The method was found to be precise, accurate, linear and robust. The proposed method was successfully employed for estimation of Ranitidine impurities in pharmaceutical preparations." @default.
- W2020159512 created "2016-06-24" @default.
- W2020159512 creator A5023640577 @default.
- W2020159512 creator A5027056220 @default.
- W2020159512 creator A5044493704 @default.
- W2020159512 creator A5069455191 @default.
- W2020159512 creator A5077625802 @default.
- W2020159512 date "2011-01-01" @default.
- W2020159512 modified "2023-10-16" @default.
- W2020159512 title "A Validated Stability-Indicating Liquid-Chromatographic Method for Ranitidine Hydrochloride in Liquid Oral Dosage Form" @default.
- W2020159512 cites W1974827890 @default.
- W2020159512 cites W2028058056 @default.
- W2020159512 cites W2044652633 @default.
- W2020159512 cites W2045431053 @default.
- W2020159512 cites W2091165980 @default.
- W2020159512 doi "https://doi.org/10.3797/scipharm.1101-06" @default.
- W2020159512 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3134857" @default.
- W2020159512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21773068" @default.
- W2020159512 hasPublicationYear "2011" @default.
- W2020159512 type Work @default.
- W2020159512 sameAs 2020159512 @default.
- W2020159512 citedByCount "7" @default.
- W2020159512 countsByYear W20201595122013 @default.
- W2020159512 countsByYear W20201595122014 @default.
- W2020159512 countsByYear W20201595122015 @default.
- W2020159512 countsByYear W20201595122020 @default.
- W2020159512 countsByYear W20201595122021 @default.
- W2020159512 countsByYear W20201595122023 @default.
- W2020159512 crossrefType "journal-article" @default.
- W2020159512 hasAuthorship W2020159512A5023640577 @default.
- W2020159512 hasAuthorship W2020159512A5027056220 @default.
- W2020159512 hasAuthorship W2020159512A5044493704 @default.
- W2020159512 hasAuthorship W2020159512A5069455191 @default.
- W2020159512 hasAuthorship W2020159512A5077625802 @default.
- W2020159512 hasBestOaLocation W20201595122 @default.
- W2020159512 hasConcept C119128265 @default.
- W2020159512 hasConcept C185592680 @default.
- W2020159512 hasConcept C23531484 @default.
- W2020159512 hasConcept C2777445857 @default.
- W2020159512 hasConcept C2777682752 @default.
- W2020159512 hasConcept C43617362 @default.
- W2020159512 hasConcept C71924100 @default.
- W2020159512 hasConcept C77281830 @default.
- W2020159512 hasConcept C98274493 @default.
- W2020159512 hasConceptScore W2020159512C119128265 @default.
- W2020159512 hasConceptScore W2020159512C185592680 @default.
- W2020159512 hasConceptScore W2020159512C23531484 @default.
- W2020159512 hasConceptScore W2020159512C2777445857 @default.
- W2020159512 hasConceptScore W2020159512C2777682752 @default.
- W2020159512 hasConceptScore W2020159512C43617362 @default.
- W2020159512 hasConceptScore W2020159512C71924100 @default.
- W2020159512 hasConceptScore W2020159512C77281830 @default.
- W2020159512 hasConceptScore W2020159512C98274493 @default.
- W2020159512 hasIssue "2" @default.
- W2020159512 hasLocation W20201595121 @default.
- W2020159512 hasLocation W20201595122 @default.
- W2020159512 hasLocation W20201595123 @default.
- W2020159512 hasLocation W20201595124 @default.
- W2020159512 hasOpenAccess W2020159512 @default.
- W2020159512 hasPrimaryLocation W20201595121 @default.
- W2020159512 hasRelatedWork W1980714464 @default.
- W2020159512 hasRelatedWork W2000038929 @default.
- W2020159512 hasRelatedWork W205088884 @default.
- W2020159512 hasRelatedWork W2052374183 @default.
- W2020159512 hasRelatedWork W2594530665 @default.
- W2020159512 hasRelatedWork W2913656258 @default.
- W2020159512 hasRelatedWork W3088073070 @default.
- W2020159512 hasRelatedWork W3212010668 @default.
- W2020159512 hasRelatedWork W2135139806 @default.
- W2020159512 hasRelatedWork W2184619360 @default.
- W2020159512 hasVolume "79" @default.
- W2020159512 isParatext "false" @default.
- W2020159512 isRetracted "false" @default.
- W2020159512 magId "2020159512" @default.
- W2020159512 workType "article" @default.