FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020164169> ?p ?o ?g. }

• W2020164169 endingPage "849" @default.
• W2020164169 startingPage "837" @default.
• W2020164169 abstract "PriB is a primosomal DNA replication protein required for the re-initiation of replication in bacteria. In this study, we investigated the gene expression of PriB in Klebsiella pneumoniae (KpPriB) and characterized the gene product through crystal structural and functional analyses. Quantitative polymerase chain reaction analysis (Q-PCR) indicated that the 104-aa priB was expressed in K. pneumoniae with a C(T) value of 22.4. The crystal structure of KpPriB (Protein Data Bank entry: 4APV) determined at a resolution of 2.1 Å was similar to that of Escherichia coli PriB (EcPriB). KpPriB formed a single complex with single-stranded DNA (ssDNA) of different lengths, suggesting a highly cooperative process. Structure-based mutational analysis revealed that substitution at K18, F42, R44, W47, K82, K84, or K89 but not R34 in KpPriB had a significant effect on both ssDNA and double-stranded DNA (dsDNA) binding. Based on these findings, the known ssDNA interaction sites of PriB were expanded to include R44 and F42, thus allowing nucleic acids to wrap around the whole PriB protein." @default.
• W2020164169 created "2016-06-24" @default.
• W2020164169 creator A5032324121 @default.
• W2020164169 creator A5044370400 @default.
• W2020164169 creator A5060136748 @default.
• W2020164169 creator A5076408723 @default.
• W2020164169 date "2012-09-03" @default.
• W2020164169 modified "2023-10-11" @default.
• W2020164169 title "Crystal structure and DNA-binding mode of<i>Klebsiella pneumoniae</i>primosomal PriB protein" @default.
• W2020164169 cites W10876090 @default.
• W2020164169 cites W1486829651 @default.
• W2020164169 cites W1539796472 @default.
• W2020164169 cites W1544096865 @default.
• W2020164169 cites W1570361288 @default.
• W2020164169 cites W1806123628 @default.
• W2020164169 cites W1924027056 @default.
• W2020164169 cites W1964370576 @default.
• W2020164169 cites W1965192752 @default.
• W2020164169 cites W1967073034 @default.
• W2020164169 cites W1971203189 @default.
• W2020164169 cites W1984389373 @default.
• W2020164169 cites W1994846675 @default.
• W2020164169 cites W1995017064 @default.
• W2020164169 cites W2000826427 @default.
• W2020164169 cites W2004392681 @default.
• W2020164169 cites W2009021135 @default.
• W2020164169 cites W2017713846 @default.
• W2020164169 cites W2017904568 @default.
• W2020164169 cites W2020058603 @default.
• W2020164169 cites W2025236994 @default.
• W2020164169 cites W2028941521 @default.
• W2020164169 cites W2030740739 @default.
• W2020164169 cites W2031819361 @default.
• W2020164169 cites W2036050888 @default.
• W2020164169 cites W2056058186 @default.
• W2020164169 cites W2066486415 @default.
• W2020164169 cites W2072576748 @default.
• W2020164169 cites W2078664051 @default.
• W2020164169 cites W2080476827 @default.
• W2020164169 cites W2081765867 @default.
• W2020164169 cites W2083344047 @default.
• W2020164169 cites W2085366119 @default.
• W2020164169 cites W2086902365 @default.
• W2020164169 cites W2089545337 @default.
• W2020164169 cites W2089680188 @default.
• W2020164169 cites W2091529967 @default.
• W2020164169 cites W2104247890 @default.
• W2020164169 cites W2104881338 @default.
• W2020164169 cites W2132239686 @default.
• W2020164169 cites W2135839939 @default.
• W2020164169 cites W2151161057 @default.
• W2020164169 cites W2153436893 @default.
• W2020164169 cites W2157153233 @default.
• W2020164169 cites W2161394043 @default.
• W2020164169 cites W2167790255 @default.
• W2020164169 cites W2171810840 @default.
• W2020164169 doi "https://doi.org/10.1111/gtc.12001" @default.
• W2020164169 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22938024" @default.
• W2020164169 hasPublicationYear "2012" @default.
• W2020164169 type Work @default.
• W2020164169 sameAs 2020164169 @default.
• W2020164169 citedByCount "29" @default.
• W2020164169 countsByYear W20201641692013 @default.
• W2020164169 countsByYear W20201641692014 @default.
• W2020164169 countsByYear W20201641692015 @default.
• W2020164169 countsByYear W20201641692016 @default.
• W2020164169 countsByYear W20201641692017 @default.
• W2020164169 countsByYear W20201641692018 @default.
• W2020164169 countsByYear W20201641692019 @default.
• W2020164169 countsByYear W20201641692021 @default.
• W2020164169 countsByYear W20201641692022 @default.
• W2020164169 countsByYear W20201641692023 @default.
• W2020164169 crossrefType "journal-article" @default.
• W2020164169 hasAuthorship W2020164169A5032324121 @default.
• W2020164169 hasAuthorship W2020164169A5044370400 @default.
• W2020164169 hasAuthorship W2020164169A5060136748 @default.
• W2020164169 hasAuthorship W2020164169A5076408723 @default.
• W2020164169 hasBestOaLocation W20201641691 @default.
• W2020164169 hasConcept C104317684 @default.
• W2020164169 hasConcept C153911025 @default.
• W2020164169 hasConcept C24107716 @default.
• W2020164169 hasConcept C2777058267 @default.
• W2020164169 hasConcept C547475151 @default.
• W2020164169 hasConcept C552990157 @default.
• W2020164169 hasConcept C55493867 @default.
• W2020164169 hasConcept C73573662 @default.
• W2020164169 hasConcept C86803240 @default.
• W2020164169 hasConceptScore W2020164169C104317684 @default.
• W2020164169 hasConceptScore W2020164169C153911025 @default.
• W2020164169 hasConceptScore W2020164169C24107716 @default.
• W2020164169 hasConceptScore W2020164169C2777058267 @default.
• W2020164169 hasConceptScore W2020164169C547475151 @default.
• W2020164169 hasConceptScore W2020164169C552990157 @default.
• W2020164169 hasConceptScore W2020164169C55493867 @default.
• W2020164169 hasConceptScore W2020164169C73573662 @default.
• W2020164169 hasConceptScore W2020164169C86803240 @default.
• W2020164169 hasIssue "10" @default.
• W2020164169 hasLocation W20201641691 @default.

• next