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- W2020170368 abstract "Less studied dementia subtypes, such as behavioral variant Frontotemporal Dementia (bvFTD), have been gaining prominence due to their epidemiological significance. There are but a few research studies on functional impairment in bvFTD. Objectives: 1. Characterize the functional performance of patients previously diagnosed with bvFTD, and compare their performance with that of patients with Alzheimer's disease (AD) and normal controls; 2. Examine the correlation between performance in the functional scales - Direct Assessment of Functional Status (DAFS-BR), Disability Assessment for Dementia (DAD) and Functional Activities Questionnaire (FAQ) - and cognitive performance; and 3. Evaluate the diagnostic accuracy of the DAFS-BR for detecting bvFTD and AD. The sample consisted of 96 individuals aged 45 or older, with at least two years of formal education, 31 had been diagnosed with bvFTD, 31 with AD, and 34 were healthy adults paired with the other participants for age, education. Patients with vbFTD and AD were paired for disease severity.he protocol included: sociodemographic and clinical questionnaire; 15-item Geriatric Depression Scale (GDS); Geriatric Anxiety Inventory (GAI); Addenbrooke Cognitive Examination-Revised (ACE-R), which includes the questions of the Mini Mental State Examination (MMSE); Executive Interview (EXIT-25); and the DAFS-BR. The protocol for caregivers included the Cornell Scale for Depression in Dementia, FAQ, DAD, Neuropsychiatric Inventory (NPI) and the Clinical Dementia Rating scale (CDR). Individuals in the bvFTD group had lower performance in the ′Eating′ scale of the DAFS-BR, and in ′Initiation′ and in ′Planning/Organization′ in the DAD, suggesting a higher level of dependence in bvFTD. Higher scores in the FAQ suggested that dependence in bvFTD is more pronounced. Significant correlations were found between cognitive and functional performances. The accuracy data for the DAFS-BR indicate that this scale can help identify dementia, yet it has limitations in the differential diagnosis among subtypes. Individuals with bvFTD display greater functional impairment than individuals with AD and controls. Functional assessment in bvFTD is essential because functional deficits are relevant for the diagnosis and clinical management of this subtype of dementia." @default.
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- W2020170368 date "2013-07-01" @default.
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- W2020170368 title "P4-079: Functionality and cognitive performance of patients with behavioral variant frontotemporal dementia" @default.
- W2020170368 doi "https://doi.org/10.1016/j.jalz.2013.05.1468" @default.
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