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- W2020171013 abstract "A mild, short and simple method for the small scale synthesis of pharmaceutically important 1,3-diaryl-4cyanopyrazoles 3 is reported from acetophenone arylhydrazones 1 through a two step reaction. All the title compounds have been subjected to in vitro antibacterial testing against four pathogenic strains namely, S.aureus, B.subtilis (gram positive) and gram negative bacteria namely, P.aeruginosa and E.coli. Preliminary results indicate that most of them exhibited promising activity. Two compounds, namely 1-(4-methylphenyl)-3-(4-bromophenyl)-4-cyanopyrazole 3d and 1-(4chlorophenyl)-3-phenyl-4-cyanopyrazole 3e from this series are found to be equipotent or more potent than the commercial antibiotics (Linezolid and Ciprofloxacin)." @default.
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- W2020171013 date "2009-08-11" @default.
- W2020171013 modified "2023-09-25" @default.
- W2020171013 title "ChemInform Abstract: Synthesis and Antibacterial Activity of 1,3-Diaryl-4-cyanopyrazoles." @default.
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- W2020171013 doi "https://doi.org/10.1002/chin.200932123" @default.
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