FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020172011> ?p ?o ?g. }

• W2020172011 endingPage "198" @default.
• W2020172011 startingPage "191" @default.
• W2020172011 abstract "We hypothesized that hyperbaric oxygen (HBO) enhances tryptophan (TRP) flux through the kynurenine (KYN) pathway because oxygen is a substrate for four pathway enzymes. Our objective was to compare the biosynthesis of KYN pathway intermediates by rat brain and liver slices with air or HBO as the gas phase. One-millimeter thick liver and brain slices were obtained from male Sprague-Dawley rats and incubated individually in chambers containing Hanks'-HEPES- buffer with (3)H-TRP (30 Ci/mmol) for 2 h (37 degrees C) in either room air or oxygen (1.2 or 5.2 atmospheres absolute [ATA] oxygen). After incubation, tissue was snap-frozen and analyzed for protein content while medium was extracted for high-performance liquid chromatography analysis. Radiolabeled nicotinamide adenine dinucleotide (NAD) was produced by brain and liver; liver (with air as the gas phase) also produced quinolinic acid (QA). HBO at 1.2 and 5.2 ATA caused increased QA and NAD from liver slices. HBO did not affect KYN metabolism in brain slices, although there was decreased production of NAD during high oxygen. We conclude that rat brain and liver contain the complete KYN pathway and that HBO enhances KYN flux in liver tissue." @default.
• W2020172011 created "2016-06-24" @default.
• W2020172011 creator A5034568902 @default.
• W2020172011 creator A5059158255 @default.
• W2020172011 creator A5078870640 @default.
• W2020172011 date "2000-07-01" @default.
• W2020172011 modified "2023-10-16" @default.
• W2020172011 title "Tryptophan metabolism through the kynurenine pathway in rat brain and liver slices" @default.
• W2020172011 cites W150072506 @default.
• W2020172011 cites W1516505350 @default.
• W2020172011 cites W1545377990 @default.
• W2020172011 cites W173017878 @default.
• W2020172011 cites W1833773432 @default.
• W2020172011 cites W1969388943 @default.
• W2020172011 cites W1973126706 @default.
• W2020172011 cites W1973250676 @default.
• W2020172011 cites W1974979364 @default.
• W2020172011 cites W1976259414 @default.
• W2020172011 cites W1983414504 @default.
• W2020172011 cites W1988409390 @default.
• W2020172011 cites W1996465026 @default.
• W2020172011 cites W1997863414 @default.
• W2020172011 cites W1998974416 @default.
• W2020172011 cites W2015145167 @default.
• W2020172011 cites W2016293448 @default.
• W2020172011 cites W2016841149 @default.
• W2020172011 cites W2019896142 @default.
• W2020172011 cites W2020693259 @default.
• W2020172011 cites W2027762021 @default.
• W2020172011 cites W2034646599 @default.
• W2020172011 cites W2055431131 @default.
• W2020172011 cites W2060331962 @default.
• W2020172011 cites W2068304272 @default.
• W2020172011 cites W2075262140 @default.
• W2020172011 cites W2082134472 @default.
• W2020172011 cites W2084740882 @default.
• W2020172011 cites W2111554792 @default.
• W2020172011 cites W2124696629 @default.
• W2020172011 cites W2153657162 @default.
• W2020172011 cites W2180755083 @default.
• W2020172011 cites W2283918746 @default.
• W2020172011 cites W2464500916 @default.
• W2020172011 cites W269427556 @default.
• W2020172011 cites W4212867161 @default.
• W2020172011 doi "https://doi.org/10.1016/s0891-5849(00)00341-5" @default.
• W2020172011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10980407" @default.
• W2020172011 hasPublicationYear "2000" @default.
• W2020172011 type Work @default.
• W2020172011 sameAs 2020172011 @default.
• W2020172011 citedByCount "26" @default.
• W2020172011 countsByYear W20201720112012 @default.
• W2020172011 countsByYear W20201720112013 @default.
• W2020172011 countsByYear W20201720112014 @default.
• W2020172011 countsByYear W20201720112015 @default.
• W2020172011 countsByYear W20201720112017 @default.
• W2020172011 countsByYear W20201720112019 @default.
• W2020172011 countsByYear W20201720112021 @default.
• W2020172011 countsByYear W20201720112022 @default.
• W2020172011 countsByYear W20201720112023 @default.
• W2020172011 crossrefType "journal-article" @default.
• W2020172011 hasAuthorship W2020172011A5034568902 @default.
• W2020172011 hasAuthorship W2020172011A5059158255 @default.
• W2020172011 hasAuthorship W2020172011A5078870640 @default.
• W2020172011 hasConcept C178790620 @default.
• W2020172011 hasConcept C181199279 @default.
• W2020172011 hasConcept C185592680 @default.
• W2020172011 hasConcept C192989942 @default.
• W2020172011 hasConcept C2776706248 @default.
• W2020172011 hasConcept C2776710720 @default.
• W2020172011 hasConcept C2776901170 @default.
• W2020172011 hasConcept C2777503454 @default.
• W2020172011 hasConcept C2777896816 @default.
• W2020172011 hasConcept C2779728014 @default.
• W2020172011 hasConcept C515207424 @default.
• W2020172011 hasConcept C540031477 @default.
• W2020172011 hasConcept C553450214 @default.
• W2020172011 hasConcept C55493867 @default.
• W2020172011 hasConcept C62231903 @default.
• W2020172011 hasConcept C68709404 @default.
• W2020172011 hasConcept C75520062 @default.
• W2020172011 hasConceptScore W2020172011C178790620 @default.
• W2020172011 hasConceptScore W2020172011C181199279 @default.
• W2020172011 hasConceptScore W2020172011C185592680 @default.
• W2020172011 hasConceptScore W2020172011C192989942 @default.
• W2020172011 hasConceptScore W2020172011C2776706248 @default.
• W2020172011 hasConceptScore W2020172011C2776710720 @default.
• W2020172011 hasConceptScore W2020172011C2776901170 @default.
• W2020172011 hasConceptScore W2020172011C2777503454 @default.
• W2020172011 hasConceptScore W2020172011C2777896816 @default.
• W2020172011 hasConceptScore W2020172011C2779728014 @default.
• W2020172011 hasConceptScore W2020172011C515207424 @default.
• W2020172011 hasConceptScore W2020172011C540031477 @default.
• W2020172011 hasConceptScore W2020172011C553450214 @default.
• W2020172011 hasConceptScore W2020172011C55493867 @default.
• W2020172011 hasConceptScore W2020172011C62231903 @default.
• W2020172011 hasConceptScore W2020172011C68709404 @default.
• W2020172011 hasConceptScore W2020172011C75520062 @default.
• W2020172011 hasIssue "2" @default.

• next