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- W2020177281 abstract "DNA amplification by the polymerase chain reaction (PCR) is a method capable of producing a selective and very high enrichment of a specific DNA sequence. Hence it seems to be useful in various fields from basic research to clinical applications. In order to automatize PCR we assembled for a very low cost a mechanical system designed to carry a test tube holder successively in three thermal baths set at the required temperatures for the reaction. Two examples of the use of this machine are given: (i) amplification of DNA of a particular subtype of acute intermittent porphyria; (ii) the detection of the chimeric c-abl/bcr message found in chronic myelogenous leukemia cells." @default.
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- W2020177281 date "1989-05-01" @default.
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- W2020177281 title "An efficient laboratory made apparatus for DNA amplification" @default.
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- W2020177281 doi "https://doi.org/10.1016/0165-022x(89)90007-9" @default.
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