Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020180904> ?p ?o ?g. }
- W2020180904 endingPage "36" @default.
- W2020180904 startingPage "31" @default.
- W2020180904 abstract "Designed for general chemical recognition, the mammalian olfactory system shares many similarities with the immune system. Among these is the popular notion that a single olfactory sensory neuron expresses a single odorant receptor gene, while all other approximately 1000 genes of this type remain silent. Here, I examine the evidence supporting the one receptor-one neuron hypothesis. I conclude that, contrary to widespread belief, it is far from being proven. I propose an hypothesis of a developmental phase of oligogenic expression that is followed by positive and negative selection resulting usually in cells with one expressed receptor. Curiously, selective processes are well established and widely accepted for lymphocytes, but these concepts are essentially ignored for olfactory sensory neurons, despite the analogies that are frequently made between these two systems. More attention must be paid to odorant receptor gene choice and expression during development and neuronal differentiation." @default.
- W2020180904 created "2016-06-24" @default.
- W2020180904 creator A5047021234 @default.
- W2020180904 date "2004-02-01" @default.
- W2020180904 modified "2023-10-17" @default.
- W2020180904 title "Odorant receptor gene choice in olfactory sensory neurons: the one receptor–one neuron hypothesis revisited" @default.
- W2020180904 cites W1483715699 @default.
- W2020180904 cites W1541120376 @default.
- W2020180904 cites W1578135208 @default.
- W2020180904 cites W1584206148 @default.
- W2020180904 cites W1603858169 @default.
- W2020180904 cites W1638185552 @default.
- W2020180904 cites W1740677000 @default.
- W2020180904 cites W1923589122 @default.
- W2020180904 cites W1946401635 @default.
- W2020180904 cites W1959867711 @default.
- W2020180904 cites W1970256374 @default.
- W2020180904 cites W1974326501 @default.
- W2020180904 cites W1987265928 @default.
- W2020180904 cites W2008118471 @default.
- W2020180904 cites W2017018649 @default.
- W2020180904 cites W2018825127 @default.
- W2020180904 cites W2020680391 @default.
- W2020180904 cites W2041125993 @default.
- W2020180904 cites W2053733982 @default.
- W2020180904 cites W2054371560 @default.
- W2020180904 cites W2065384973 @default.
- W2020180904 cites W2069186336 @default.
- W2020180904 cites W2072248036 @default.
- W2020180904 cites W2074485622 @default.
- W2020180904 cites W2079200857 @default.
- W2020180904 cites W2079589334 @default.
- W2020180904 cites W2082137952 @default.
- W2020180904 cites W2089193539 @default.
- W2020180904 cites W2089340953 @default.
- W2020180904 cites W2092132067 @default.
- W2020180904 cites W2092937322 @default.
- W2020180904 cites W2097186487 @default.
- W2020180904 cites W2116487174 @default.
- W2020180904 cites W2121549707 @default.
- W2020180904 cites W2122659024 @default.
- W2020180904 cites W2127751164 @default.
- W2020180904 cites W2133831748 @default.
- W2020180904 cites W2134891904 @default.
- W2020180904 cites W2135358991 @default.
- W2020180904 cites W2136791900 @default.
- W2020180904 cites W2156344024 @default.
- W2020180904 cites W2161659751 @default.
- W2020180904 cites W2164101639 @default.
- W2020180904 cites W2171898831 @default.
- W2020180904 cites W4237756592 @default.
- W2020180904 doi "https://doi.org/10.1016/j.conb.2004.01.014" @default.
- W2020180904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15018935" @default.
- W2020180904 hasPublicationYear "2004" @default.
- W2020180904 type Work @default.
- W2020180904 sameAs 2020180904 @default.
- W2020180904 citedByCount "256" @default.
- W2020180904 countsByYear W20201809042012 @default.
- W2020180904 countsByYear W20201809042013 @default.
- W2020180904 countsByYear W20201809042014 @default.
- W2020180904 countsByYear W20201809042015 @default.
- W2020180904 countsByYear W20201809042016 @default.
- W2020180904 countsByYear W20201809042017 @default.
- W2020180904 countsByYear W20201809042018 @default.
- W2020180904 countsByYear W20201809042019 @default.
- W2020180904 countsByYear W20201809042020 @default.
- W2020180904 countsByYear W20201809042021 @default.
- W2020180904 countsByYear W20201809042022 @default.
- W2020180904 countsByYear W20201809042023 @default.
- W2020180904 crossrefType "journal-article" @default.
- W2020180904 hasAuthorship W2020180904A5047021234 @default.
- W2020180904 hasConcept C104317684 @default.
- W2020180904 hasConcept C169760540 @default.
- W2020180904 hasConcept C170493617 @default.
- W2020180904 hasConcept C201792869 @default.
- W2020180904 hasConcept C2775908076 @default.
- W2020180904 hasConcept C2777815949 @default.
- W2020180904 hasConcept C2778794669 @default.
- W2020180904 hasConcept C2779980732 @default.
- W2020180904 hasConcept C54355233 @default.
- W2020180904 hasConcept C86803240 @default.
- W2020180904 hasConcept C94487597 @default.
- W2020180904 hasConceptScore W2020180904C104317684 @default.
- W2020180904 hasConceptScore W2020180904C169760540 @default.
- W2020180904 hasConceptScore W2020180904C170493617 @default.
- W2020180904 hasConceptScore W2020180904C201792869 @default.
- W2020180904 hasConceptScore W2020180904C2775908076 @default.
- W2020180904 hasConceptScore W2020180904C2777815949 @default.
- W2020180904 hasConceptScore W2020180904C2778794669 @default.
- W2020180904 hasConceptScore W2020180904C2779980732 @default.
- W2020180904 hasConceptScore W2020180904C54355233 @default.
- W2020180904 hasConceptScore W2020180904C86803240 @default.
- W2020180904 hasConceptScore W2020180904C94487597 @default.
- W2020180904 hasIssue "1" @default.
- W2020180904 hasLocation W20201809041 @default.
- W2020180904 hasLocation W20201809042 @default.
- W2020180904 hasOpenAccess W2020180904 @default.
- W2020180904 hasPrimaryLocation W20201809041 @default.