FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020181594> ?p ?o ?g. }

• W2020181594 endingPage "25" @default.
• W2020181594 startingPage "21" @default.
• W2020181594 abstract "Gemcitabine (GEMZAR) is a novel nucleoside analogue with activity in a range of preclinical models both in vitro and in vivo. It is highly schedule dependent, with weekly x3 every 4 weeks being the recommended schedule for phase II/III studies. Early phase II trials identified activity against non-small-cell lung cancer and pancreatic cancers, tumour types for which gemcitabine has a licence for treatment in many countries. However, the preclinical models indicated that gemcitabine may be active against many other human solid tumours. In phase II studies, activity has been identified against breast cancer, both as a single agent and in combination. In bladder cancer, impressive single-agent activity of gemcitabine has also been seen, as well as in combination with cisplatin, initially in MVAC and platinum failures but more recently as first-line therapy both as a single agent and combined with cisplatin. Anti-tumour activity has also been seen in patients with ovarian cancer, head and neck cancer, small-cell lung cancer and cervical cancer, with minimal activity in renal carcinoma, prostate and colon cancer. In view of the excellent side-effect profile and the potential for gemcitabine to inhibit DNA repair after exposure to DNA-damaging agents, further developments of gemcitabine will include its use in combination chemotherapy and combined modality schedules." @default.
• W2020181594 created "2016-06-24" @default.
• W2020181594 creator A5080571689 @default.
• W2020181594 date "1998-01-01" @default.
• W2020181594 modified "2023-10-06" @default.
• W2020181594 title "The role of gemcitabine in the treatment of other tumours" @default.
• W2020181594 cites W1527742565 @default.
• W2020181594 cites W1795204252 @default.
• W2020181594 cites W1812067939 @default.
• W2020181594 cites W1857358013 @default.
• W2020181594 cites W1858072261 @default.
• W2020181594 cites W1931508686 @default.
• W2020181594 cites W1938837918 @default.
• W2020181594 cites W1944650458 @default.
• W2020181594 cites W2001996041 @default.
• W2020181594 cites W2018732348 @default.
• W2020181594 cites W2052846363 @default.
• W2020181594 cites W2084562398 @default.
• W2020181594 cites W2120150472 @default.
• W2020181594 cites W2130164889 @default.
• W2020181594 cites W2154737435 @default.
• W2020181594 cites W2262092684 @default.
• W2020181594 cites W2268861790 @default.
• W2020181594 cites W2270490184 @default.
• W2020181594 cites W2395412721 @default.
• W2020181594 cites W2395499508 @default.
• W2020181594 cites W2401812172 @default.
• W2020181594 cites W2419379036 @default.
• W2020181594 doi "https://doi.org/10.1038/bjc.1998.750" @default.
• W2020181594 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2062798" @default.
• W2020181594 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9717987" @default.
• W2020181594 hasPublicationYear "1998" @default.
• W2020181594 type Work @default.
• W2020181594 sameAs 2020181594 @default.
• W2020181594 citedByCount "111" @default.
• W2020181594 countsByYear W20201815942012 @default.
• W2020181594 countsByYear W20201815942013 @default.
• W2020181594 countsByYear W20201815942014 @default.
• W2020181594 countsByYear W20201815942015 @default.
• W2020181594 countsByYear W20201815942016 @default.
• W2020181594 countsByYear W20201815942017 @default.
• W2020181594 countsByYear W20201815942019 @default.
• W2020181594 countsByYear W20201815942020 @default.
• W2020181594 countsByYear W20201815942021 @default.
• W2020181594 countsByYear W20201815942022 @default.
• W2020181594 crossrefType "journal-article" @default.
• W2020181594 hasAuthorship W2020181594A5080571689 @default.
• W2020181594 hasBestOaLocation W20201815942 @default.
• W2020181594 hasConcept C121608353 @default.
• W2020181594 hasConcept C126322002 @default.
• W2020181594 hasConcept C143998085 @default.
• W2020181594 hasConcept C150903083 @default.
• W2020181594 hasConcept C207001950 @default.
• W2020181594 hasConcept C2776256026 @default.
• W2020181594 hasConcept C2776530083 @default.
• W2020181594 hasConcept C2776543447 @default.
• W2020181594 hasConcept C2776694085 @default.
• W2020181594 hasConcept C2777333352 @default.
• W2020181594 hasConcept C2777844706 @default.
• W2020181594 hasConcept C2778239845 @default.
• W2020181594 hasConcept C2780192828 @default.
• W2020181594 hasConcept C2780210213 @default.
• W2020181594 hasConcept C2780258809 @default.
• W2020181594 hasConcept C2780352672 @default.
• W2020181594 hasConcept C2780427987 @default.
• W2020181594 hasConcept C502942594 @default.
• W2020181594 hasConcept C55493867 @default.
• W2020181594 hasConcept C71924100 @default.
• W2020181594 hasConcept C86803240 @default.
• W2020181594 hasConcept C98274493 @default.
• W2020181594 hasConceptScore W2020181594C121608353 @default.
• W2020181594 hasConceptScore W2020181594C126322002 @default.
• W2020181594 hasConceptScore W2020181594C143998085 @default.
• W2020181594 hasConceptScore W2020181594C150903083 @default.
• W2020181594 hasConceptScore W2020181594C207001950 @default.
• W2020181594 hasConceptScore W2020181594C2776256026 @default.
• W2020181594 hasConceptScore W2020181594C2776530083 @default.
• W2020181594 hasConceptScore W2020181594C2776543447 @default.
• W2020181594 hasConceptScore W2020181594C2776694085 @default.
• W2020181594 hasConceptScore W2020181594C2777333352 @default.
• W2020181594 hasConceptScore W2020181594C2777844706 @default.
• W2020181594 hasConceptScore W2020181594C2778239845 @default.
• W2020181594 hasConceptScore W2020181594C2780192828 @default.
• W2020181594 hasConceptScore W2020181594C2780210213 @default.
• W2020181594 hasConceptScore W2020181594C2780258809 @default.
• W2020181594 hasConceptScore W2020181594C2780352672 @default.
• W2020181594 hasConceptScore W2020181594C2780427987 @default.
• W2020181594 hasConceptScore W2020181594C502942594 @default.
• W2020181594 hasConceptScore W2020181594C55493867 @default.
• W2020181594 hasConceptScore W2020181594C71924100 @default.
• W2020181594 hasConceptScore W2020181594C86803240 @default.
• W2020181594 hasConceptScore W2020181594C98274493 @default.
• W2020181594 hasIssue "S3" @default.
• W2020181594 hasLocation W20201815941 @default.
• W2020181594 hasLocation W20201815942 @default.
• W2020181594 hasLocation W20201815943 @default.
• W2020181594 hasLocation W20201815944 @default.
• W2020181594 hasOpenAccess W2020181594 @default.

• next