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• W2020195718 abstract "The antiarrhythmic properties of n-3 polyunsaturated fatty acids (PUFAs) have been demonstrated in experimental models and in patients with coronary artery disease [ 1 Kang J.X. Leaf A. Evidence that free polyunsaturated fatty acids modify Na+ channels by directly binding to the channel proteins. Proc Natl Acad Sci USA. 1996; 93: 3542-3546 Crossref PubMed Scopus (173) Google Scholar , 2 Christensen J.H. Gustenhoff P. Korup E. et al. Effect of fish oil on heart rate variability in survivors of myocardial infarction: a double blind randomised controlled trial. BMJ. 1996; 312: 677-678 Crossref PubMed Scopus (220) Google Scholar , 3 Christensen J.H. Korup E. Aaroe J. et al. Fish consumption, n-3 fatty acids in cell membranes, and heart rate variability in survivors of myocardial infarction with left ventricular dysfunction. Am J Cardiol. 1997; 79: 1670-1673 Abstract Full Text Full Text PDF PubMed Scopus (168) Google Scholar , 4 Leaf A. Kang J.K. Xiao Y.F. Billman G.E. Clinical prevention of sudden cardiac death by n-3 polyunsaturated fatty acids and mechanism of prevention of arrhythmias by n-3 fish oils. Circulation. 2003; 107: 2646-2652 Crossref PubMed Google Scholar , 5 Mozaffarian D. Stein P.K. Prineas R.J. Siscovick D.S. Dietary fish and omega-3 fatty acid consumption and heart rate variability in US adults. Circulation. 2008; 117: 1130-1137 Crossref PubMed Scopus (118) Google Scholar , 6 Mozzaffarian D. Psaty B.M. Rimm E.B. et al. Fish intake and risk of incident atrial fibrillation. Circulation. 2004; 110: 368-373 Crossref PubMed Scopus (394) Google Scholar ]. On the other hand, the signal-averaged electrocardiogram (SAECG) of the P waves has been used to predict the development of atrial fibrillation by measuring the filtered P wave duration (FPD) as an index of atrial conduction delay with high accuracy [ 7 Guidera S.A. Steinberg J.S. The signal averaged P wave duration: a rapid and noninvasive marker of risk of atrial fibrillation. J Am Coll Cardiol. 1993; 21: 1645-1651 Abstract Full Text PDF PubMed Scopus (200) Google Scholar , 8 Montereggi A. Marconi P. Olivotto L. et al. Signal-averaged P-wave duration and risk of paroxysmal atrial fibrillation in hyperthyroidism. Am J Cardiol. 1996; 77: 266-269 Abstract Full Text PDF PubMed Scopus (57) Google Scholar , 9 Yamada T. Fukumani M. Shimonagata T. et al. Prediction of paroxysmal atrial fibrillation in patients with congestive heart failure: a prpspective study. J Am Coll Cardiol. 2000; 35: 405-413 Abstract Full Text Full Text PDF PubMed Scopus (111) Google Scholar , 10 Darbar D. Jahangir A. Hammill S.C. Gersh B.J. P wave signal-averaged electrocardiography to identify risk for atrial fibrillation. PACE. 2002; 25: 1447-1453 Crossref Scopus (65) Google Scholar ]. In this study, we assessed whether key long-chain n-3 PUFA, eicosapentaenoic acid (EPA) affected parameters of P wave SAECG in patients with coronary artery disease." @default.
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• W2020195718 date "2012-01-01" @default.
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• W2020195718 title "Short-term effects of eicosapentaenoic acid on P wave signal-averaged electrocardiogram in patients with coronary artery disease" @default.
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• W2020195718 doi "https://doi.org/10.1016/j.ijcard.2011.10.068" @default.
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