Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020213039> ?p ?o ?g. }
- W2020213039 endingPage "869" @default.
- W2020213039 startingPage "865" @default.
- W2020213039 abstract "Antimicrobial peptides are important components of innate immunity, especially in the unique environment of the oral cavity. Lack of the human cathelicidin LL-37 has been implicated in severe periodontitis, whilst high salivary levels of LL-37 seem to increase caries resistance. Limited data exists about the concentration of LL-37 in saliva of young children. In this study, the salivary concentration of LL-37 was examined in relation to age, gender, type of dentition (primary, mixed or permanent) and caries experience of children. Unstimulated whole saliva was collected from 49 systemically healthy and gingivitis free children aged 2–18 years old. Their caries activity was recorded. The salivary LL-37 concentration was determined by enzyme linked immunosorbent assay (ELISA). LL-37 was detected in all saliva samples. Its concentration varied widely, with girls exhibiting higher peptide levels than boys. A positive correlation of the LL-37 concentration was observed with age. Children with primary dentition had significantly lower peptide concentration than those with mixed or permanent dentition. Significantly lower concentrations of LL-37 were also found in children with high caries activity, compared to caries free children or to children with low to moderate caries activity. Our results reinforce the belief that LL-37 is an important molecule of immunity in the oral environment and it seems to play a protective role against caries." @default.
- W2020213039 created "2016-06-24" @default.
- W2020213039 creator A5015482528 @default.
- W2020213039 creator A5076742854 @default.
- W2020213039 creator A5088171991 @default.
- W2020213039 creator A5088821589 @default.
- W2020213039 date "2012-07-01" @default.
- W2020213039 modified "2023-10-16" @default.
- W2020213039 title "Salivary concentration of the antimicrobial peptide LL-37 in children" @default.
- W2020213039 cites W1587526075 @default.
- W2020213039 cites W1783560840 @default.
- W2020213039 cites W1799680372 @default.
- W2020213039 cites W1970108302 @default.
- W2020213039 cites W1970506139 @default.
- W2020213039 cites W1974904214 @default.
- W2020213039 cites W1984439119 @default.
- W2020213039 cites W1985759004 @default.
- W2020213039 cites W1990880480 @default.
- W2020213039 cites W1994141994 @default.
- W2020213039 cites W1999676604 @default.
- W2020213039 cites W2011336106 @default.
- W2020213039 cites W2013075798 @default.
- W2020213039 cites W2020668335 @default.
- W2020213039 cites W2024635247 @default.
- W2020213039 cites W2027183942 @default.
- W2020213039 cites W2027498968 @default.
- W2020213039 cites W2047599457 @default.
- W2020213039 cites W2057198053 @default.
- W2020213039 cites W2063116767 @default.
- W2020213039 cites W2065844463 @default.
- W2020213039 cites W2067778091 @default.
- W2020213039 cites W2069492069 @default.
- W2020213039 cites W2075061399 @default.
- W2020213039 cites W2079469789 @default.
- W2020213039 cites W2079692416 @default.
- W2020213039 cites W2091858071 @default.
- W2020213039 cites W2092221483 @default.
- W2020213039 cites W2093290488 @default.
- W2020213039 cites W2097832355 @default.
- W2020213039 cites W2111047538 @default.
- W2020213039 cites W2116558722 @default.
- W2020213039 cites W2116911624 @default.
- W2020213039 cites W2121050439 @default.
- W2020213039 cites W2126466156 @default.
- W2020213039 cites W2126567206 @default.
- W2020213039 cites W2128845918 @default.
- W2020213039 cites W2139212892 @default.
- W2020213039 cites W2139577629 @default.
- W2020213039 cites W2140151651 @default.
- W2020213039 cites W2142181216 @default.
- W2020213039 cites W2144610619 @default.
- W2020213039 cites W2149168973 @default.
- W2020213039 cites W2151730461 @default.
- W2020213039 cites W2152978370 @default.
- W2020213039 cites W2153601290 @default.
- W2020213039 cites W2161180045 @default.
- W2020213039 cites W2165493879 @default.
- W2020213039 doi "https://doi.org/10.1016/j.archoralbio.2012.01.008" @default.
- W2020213039 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22336091" @default.
- W2020213039 hasPublicationYear "2012" @default.
- W2020213039 type Work @default.
- W2020213039 sameAs 2020213039 @default.
- W2020213039 citedByCount "58" @default.
- W2020213039 countsByYear W20202130392012 @default.
- W2020213039 countsByYear W20202130392013 @default.
- W2020213039 countsByYear W20202130392014 @default.
- W2020213039 countsByYear W20202130392015 @default.
- W2020213039 countsByYear W20202130392016 @default.
- W2020213039 countsByYear W20202130392017 @default.
- W2020213039 countsByYear W20202130392018 @default.
- W2020213039 countsByYear W20202130392019 @default.
- W2020213039 countsByYear W20202130392020 @default.
- W2020213039 countsByYear W20202130392021 @default.
- W2020213039 countsByYear W20202130392022 @default.
- W2020213039 countsByYear W20202130392023 @default.
- W2020213039 crossrefType "journal-article" @default.
- W2020213039 hasAuthorship W2020213039A5015482528 @default.
- W2020213039 hasAuthorship W2020213039A5076742854 @default.
- W2020213039 hasAuthorship W2020213039A5088171991 @default.
- W2020213039 hasAuthorship W2020213039A5088821589 @default.
- W2020213039 hasConcept C126322002 @default.
- W2020213039 hasConcept C136449434 @default.
- W2020213039 hasConcept C185592680 @default.
- W2020213039 hasConcept C188126409 @default.
- W2020213039 hasConcept C199343813 @default.
- W2020213039 hasConcept C203014093 @default.
- W2020213039 hasConcept C2777379352 @default.
- W2020213039 hasConcept C2778430296 @default.
- W2020213039 hasConcept C2779281246 @default.
- W2020213039 hasConcept C2780385504 @default.
- W2020213039 hasConcept C2780791200 @default.
- W2020213039 hasConcept C42407357 @default.
- W2020213039 hasConcept C4937899 @default.
- W2020213039 hasConcept C504460877 @default.
- W2020213039 hasConcept C523546767 @default.
- W2020213039 hasConcept C54355233 @default.
- W2020213039 hasConcept C55493867 @default.
- W2020213039 hasConcept C71924100 @default.