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• W2020229076 abstract "Because estrogen may influence brain blood flow and metabolism in older adults, we used positron emission tomography to evaluate cerebral glucose metabolic change in post-menopausal women and men. Women estrogen users (n=4), women non-users (n=8) and men (n=10) were scanned at baseline and two years later. Analyses focused on glucose metabolism in lateral temporal, inferior parietal and posterior cingulate brain regions, previously reported to decline in non-demented older persons. No metabolic differences in cerebral regions of interest were found among groups at baseline. At follow-up, women estrogen users showed significantly increased glucose metabolism in the lateral temporal region, whereas women non-users and men exhibited no significant metabolic change in this region. These findings suggest that estrogen use may protect against regional cerebral metabolic decline in postmenopausal women." @default.
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• W2020229076 date "2001-07-01" @default.
• W2020229076 modified "2023-10-18" @default.
• W2020229076 title "Estrogen use and brain metabolic change in older adults. A preliminary report" @default.
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• W2020229076 doi "https://doi.org/10.1016/s0925-4927(01)00084-1" @default.
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