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- W2020240051 abstract "The design rationale, synthesis, and preliminary radiolabeling evaluation of new N,N,O-type pyridyl−tert-nitrogen−phenol ligands for the [M(CO)3]+ core, where M = 99mTc or Re, are described. The capability of the ligands to bind this technetium core is initially demonstrated by using the cold surrogate [Re(CO)3]+. NMR studies of the relevant rhenium tricarbonyl complexes indicate the formation of either a monomeric or a possible dimeric complex with each phenolic O atom bridging between two metal centers. Labeling with [99mTc(CO)3]+ provided further insight into the differences in complex formation on the dilute, no carrier added, level compared to the macroscopic scale at which the ReI counterparts were made. These new tridentate, monoanionic ligands are competent chelates in binding the [99mTc(CO)3]+ core because radiolabeling yields ranged from 85 to 99% and the resulting complexes were stable to cysteine and histidine challenges for as long as 24 h." @default.
- W2020240051 created "2016-06-24" @default.
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- W2020240051 date "2008-01-12" @default.
- W2020240051 modified "2023-09-26" @default.
- W2020240051 title "Pyridine−<i>tert</i>-Nitrogen−Phenol Ligands: N,N,O-Type Tripodal Chelates for the [M(CO)<sub>3</sub>]<sup>+</sup> Core (M = Re, Tc)" @default.
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- W2020240051 doi "https://doi.org/10.1021/ic701822n" @default.
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