FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020263757> ?p ?o ?g. }

• W2020263757 endingPage "1418" @default.
• W2020263757 startingPage "1413" @default.
• W2020263757 abstract "The thermodynamics of double-helix formation by (dG-dC)3 have been measured in aqueous solvent mixtures containing 10 mol % methanol, ethanol, 1-propanol, formamide, N,N-dimethylformamide, or urea and 20 mol % ethanol. Optical activity measurements indicate the conformation of the double helix at 3 degree C is the same in all the solvent mixtures except 20 mol % ethanol. All the cosolvents destabilize the helix relative to water. With 10 mol % alcohol cosolvents, this destabilization is associated with a more unfavorable entropy change averaging approximately 8% and a more favorable enthalpy change averaging approximately 5%. This is consistent with a small contribution of hydrophobic bonding to stability. In contrast, the destabilization by formamide, N,N-dimethylformamide, and urea is associated with a more unfavorable enthalpy change averaging approximately 23% and a more favorable entropy change averaging approximately 21%. Since all three of these cosolvents have dipole moments larger than water, this is consistent with increased competition for dipolar interactions between the nucleic acid bases. None of the results correlate with any one bulk solvent parameter such as surface tension, viscosity, or dielectric constant. With 20 mol % ethanol, optical activity measurements are consistent with a partial B to C form transition. This is associated with a 27% less favorable enthalpy and 25% more favorable entropy for helix formation relative to water. Since the B to C transition is associated with helix dehydration, this may imply a significant contribution of bound water to stability." @default.
• W2020263757 created "2016-06-24" @default.
• W2020263757 creator A5013801926 @default.
• W2020263757 creator A5045936986 @default.
• W2020263757 date "1981-03-01" @default.
• W2020263757 modified "2023-09-23" @default.
• W2020263757 title "Solvent effects on the thermodynamics of double-helix formation in (dG-dC)3" @default.
• W2020263757 cites W1040292460 @default.
• W2020263757 cites W157808733 @default.
• W2020263757 cites W1608774300 @default.
• W2020263757 cites W1645567343 @default.
• W2020263757 cites W1967466709 @default.
• W2020263757 cites W1971481046 @default.
• W2020263757 cites W1973503110 @default.
• W2020263757 cites W1977395672 @default.
• W2020263757 cites W1977752249 @default.
• W2020263757 cites W1982845769 @default.
• W2020263757 cites W1983337217 @default.
• W2020263757 cites W1986247285 @default.
• W2020263757 cites W2002551475 @default.
• W2020263757 cites W2003826802 @default.
• W2020263757 cites W2004291098 @default.
• W2020263757 cites W2004466722 @default.
• W2020263757 cites W2014767474 @default.
• W2020263757 cites W2015967850 @default.
• W2020263757 cites W2026172443 @default.
• W2020263757 cites W2030725755 @default.
• W2020263757 cites W2041769577 @default.
• W2020263757 cites W2044815624 @default.
• W2020263757 cites W2052830722 @default.
• W2020263757 cites W2054606697 @default.
• W2020263757 cites W2055632396 @default.
• W2020263757 cites W2063412279 @default.
• W2020263757 cites W2065025926 @default.
• W2020263757 cites W2077274430 @default.
• W2020263757 cites W2077650402 @default.
• W2020263757 cites W2080821089 @default.
• W2020263757 cites W2087607974 @default.
• W2020263757 cites W2087798888 @default.
• W2020263757 cites W2088558421 @default.
• W2020263757 cites W2126058971 @default.
• W2020263757 cites W2143075134 @default.
• W2020263757 cites W2153236895 @default.
• W2020263757 cites W2166713673 @default.
• W2020263757 cites W2314060671 @default.
• W2020263757 cites W2315141432 @default.
• W2020263757 cites W2336402835 @default.
• W2020263757 cites W2949664380 @default.
• W2020263757 doi "https://doi.org/10.1021/bi00509a002" @default.
• W2020263757 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7225339" @default.
• W2020263757 hasPublicationYear "1981" @default.
• W2020263757 type Work @default.
• W2020263757 sameAs 2020263757 @default.
• W2020263757 citedByCount "47" @default.
• W2020263757 countsByYear W20202637572012 @default.
• W2020263757 countsByYear W20202637572013 @default.
• W2020263757 countsByYear W20202637572014 @default.
• W2020263757 countsByYear W20202637572015 @default.
• W2020263757 countsByYear W20202637572016 @default.
• W2020263757 countsByYear W20202637572018 @default.
• W2020263757 countsByYear W20202637572019 @default.
• W2020263757 crossrefType "journal-article" @default.
• W2020263757 hasAuthorship W2020263757A5013801926 @default.
• W2020263757 hasAuthorship W2020263757A5045936986 @default.
• W2020263757 hasConcept C121332964 @default.
• W2020263757 hasConcept C132439834 @default.
• W2020263757 hasConcept C147789679 @default.
• W2020263757 hasConcept C178790620 @default.
• W2020263757 hasConcept C184651966 @default.
• W2020263757 hasConcept C185592680 @default.
• W2020263757 hasConcept C18903297 @default.
• W2020263757 hasConcept C2777712214 @default.
• W2020263757 hasConcept C2778270854 @default.
• W2020263757 hasConcept C2778530040 @default.
• W2020263757 hasConcept C2779965526 @default.
• W2020263757 hasConcept C2780471494 @default.
• W2020263757 hasConcept C3288061 @default.
• W2020263757 hasConcept C8010536 @default.
• W2020263757 hasConcept C86803240 @default.
• W2020263757 hasConcept C97355855 @default.
• W2020263757 hasConceptScore W2020263757C121332964 @default.
• W2020263757 hasConceptScore W2020263757C132439834 @default.
• W2020263757 hasConceptScore W2020263757C147789679 @default.
• W2020263757 hasConceptScore W2020263757C178790620 @default.
• W2020263757 hasConceptScore W2020263757C184651966 @default.
• W2020263757 hasConceptScore W2020263757C185592680 @default.
• W2020263757 hasConceptScore W2020263757C18903297 @default.
• W2020263757 hasConceptScore W2020263757C2777712214 @default.
• W2020263757 hasConceptScore W2020263757C2778270854 @default.
• W2020263757 hasConceptScore W2020263757C2778530040 @default.
• W2020263757 hasConceptScore W2020263757C2779965526 @default.
• W2020263757 hasConceptScore W2020263757C2780471494 @default.
• W2020263757 hasConceptScore W2020263757C3288061 @default.
• W2020263757 hasConceptScore W2020263757C8010536 @default.
• W2020263757 hasConceptScore W2020263757C86803240 @default.
• W2020263757 hasConceptScore W2020263757C97355855 @default.
• W2020263757 hasIssue "6" @default.
• W2020263757 hasLocation W20202637571 @default.

• next