FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020264563> ?p ?o ?g. }

• W2020264563 endingPage "357" @default.
• W2020264563 startingPage "353" @default.
• W2020264563 abstract "ObjectiveTo evaluate the frequency of specific aneuploidies in miscarriages in an infertility practice and calculate the potential sensitivities of the different aneuploidy screening options for preimplantation genetic diagnosis (PGD) in this setting.DesignRetrospective analysis.SettingAcademic reproductive endocrinology and infertility practice.Patient(s)Women with miscarriages that had karyotype analysis on products of conception.Intervention(s)None.Main Outcome Measure(s)Karyotype of spontaneous abortions compared with commercially available PGD options.Result(s)Of the 273 karyotypes analyzed, 177 (64.8%) were abnormal. The average age of the patients was 37 ± 4.5 years. Using a limited five-probe panel, 54 of the 177 (31%) abnormal karyotypes would have been detected. In contrast, an extended PGD panel (using 9, 10, or 12 chromosome probes) would have detected 127, 131, and 140 of 177 abnormalities, 72%, 74%, and 79% respectively. The difference between the limited (5-probe) and extended (9-, 10-, and 12-probe) panels was statistically significant. There was not a statistically significant difference among the extended panels.Conclusion(s)Most of the abnormalities seen in miscarriages are detectable by PGD with extended panels. A significantly higher percentage of these abnormalities could be detected by screening for 9, 10, or 12 chromosomes compared with only 5. To evaluate the frequency of specific aneuploidies in miscarriages in an infertility practice and calculate the potential sensitivities of the different aneuploidy screening options for preimplantation genetic diagnosis (PGD) in this setting. Retrospective analysis. Academic reproductive endocrinology and infertility practice. Women with miscarriages that had karyotype analysis on products of conception. None. Karyotype of spontaneous abortions compared with commercially available PGD options. Of the 273 karyotypes analyzed, 177 (64.8%) were abnormal. The average age of the patients was 37 ± 4.5 years. Using a limited five-probe panel, 54 of the 177 (31%) abnormal karyotypes would have been detected. In contrast, an extended PGD panel (using 9, 10, or 12 chromosome probes) would have detected 127, 131, and 140 of 177 abnormalities, 72%, 74%, and 79% respectively. The difference between the limited (5-probe) and extended (9-, 10-, and 12-probe) panels was statistically significant. There was not a statistically significant difference among the extended panels. Most of the abnormalities seen in miscarriages are detectable by PGD with extended panels. A significantly higher percentage of these abnormalities could be detected by screening for 9, 10, or 12 chromosomes compared with only 5." @default.
• W2020264563 created "2016-06-24" @default.
• W2020264563 creator A5010600416 @default.
• W2020264563 creator A5045239530 @default.
• W2020264563 creator A5088502741 @default.
• W2020264563 date "2008-02-01" @default.
• W2020264563 modified "2023-09-23" @default.
• W2020264563 title "Aneuploidy in the miscarriages of infertile women and the potential benefit of preimplanation genetic diagnosis" @default.
• W2020264563 cites W1538732295 @default.
• W2020264563 cites W1974346013 @default.
• W2020264563 cites W1975030943 @default.
• W2020264563 cites W1982418114 @default.
• W2020264563 cites W1982939734 @default.
• W2020264563 cites W1984311091 @default.
• W2020264563 cites W1984751003 @default.
• W2020264563 cites W2005773599 @default.
• W2020264563 cites W2024500037 @default.
• W2020264563 cites W2041728351 @default.
• W2020264563 cites W2063199640 @default.
• W2020264563 cites W2088665709 @default.
• W2020264563 cites W2104330394 @default.
• W2020264563 cites W2130503128 @default.
• W2020264563 cites W2132197237 @default.
• W2020264563 cites W2152115786 @default.
• W2020264563 cites W2152830624 @default.
• W2020264563 cites W2160524881 @default.
• W2020264563 cites W2167057787 @default.
• W2020264563 cites W4251847632 @default.
• W2020264563 doi "https://doi.org/10.1016/j.fertnstert.2007.02.040" @default.
• W2020264563 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17509575" @default.
• W2020264563 hasPublicationYear "2008" @default.
• W2020264563 type Work @default.
• W2020264563 sameAs 2020264563 @default.
• W2020264563 citedByCount "65" @default.
• W2020264563 countsByYear W20202645632012 @default.
• W2020264563 countsByYear W20202645632013 @default.
• W2020264563 countsByYear W20202645632014 @default.
• W2020264563 countsByYear W20202645632015 @default.
• W2020264563 countsByYear W20202645632016 @default.
• W2020264563 countsByYear W20202645632017 @default.
• W2020264563 countsByYear W20202645632018 @default.
• W2020264563 countsByYear W20202645632019 @default.
• W2020264563 countsByYear W20202645632020 @default.
• W2020264563 countsByYear W20202645632021 @default.
• W2020264563 countsByYear W20202645632022 @default.
• W2020264563 countsByYear W20202645632023 @default.
• W2020264563 crossrefType "journal-article" @default.
• W2020264563 hasAuthorship W2020264563A5010600416 @default.
• W2020264563 hasAuthorship W2020264563A5045239530 @default.
• W2020264563 hasAuthorship W2020264563A5088502741 @default.
• W2020264563 hasConcept C104317684 @default.
• W2020264563 hasConcept C126322002 @default.
• W2020264563 hasConcept C131872663 @default.
• W2020264563 hasConcept C167135981 @default.
• W2020264563 hasConcept C2776210078 @default.
• W2020264563 hasConcept C2777338322 @default.
• W2020264563 hasConcept C2777688143 @default.
• W2020264563 hasConcept C2778580812 @default.
• W2020264563 hasConcept C2778642596 @default.
• W2020264563 hasConcept C2778805741 @default.
• W2020264563 hasConcept C2779234561 @default.
• W2020264563 hasConcept C2779672484 @default.
• W2020264563 hasConcept C2780343435 @default.
• W2020264563 hasConcept C2780673598 @default.
• W2020264563 hasConcept C29456083 @default.
• W2020264563 hasConcept C30481170 @default.
• W2020264563 hasConcept C53226629 @default.
• W2020264563 hasConcept C54355233 @default.
• W2020264563 hasConcept C71924100 @default.
• W2020264563 hasConcept C86803240 @default.
• W2020264563 hasConceptScore W2020264563C104317684 @default.
• W2020264563 hasConceptScore W2020264563C126322002 @default.
• W2020264563 hasConceptScore W2020264563C131872663 @default.
• W2020264563 hasConceptScore W2020264563C167135981 @default.
• W2020264563 hasConceptScore W2020264563C2776210078 @default.
• W2020264563 hasConceptScore W2020264563C2777338322 @default.
• W2020264563 hasConceptScore W2020264563C2777688143 @default.
• W2020264563 hasConceptScore W2020264563C2778580812 @default.
• W2020264563 hasConceptScore W2020264563C2778642596 @default.
• W2020264563 hasConceptScore W2020264563C2778805741 @default.
• W2020264563 hasConceptScore W2020264563C2779234561 @default.
• W2020264563 hasConceptScore W2020264563C2779672484 @default.
• W2020264563 hasConceptScore W2020264563C2780343435 @default.
• W2020264563 hasConceptScore W2020264563C2780673598 @default.
• W2020264563 hasConceptScore W2020264563C29456083 @default.
• W2020264563 hasConceptScore W2020264563C30481170 @default.
• W2020264563 hasConceptScore W2020264563C53226629 @default.
• W2020264563 hasConceptScore W2020264563C54355233 @default.
• W2020264563 hasConceptScore W2020264563C71924100 @default.
• W2020264563 hasConceptScore W2020264563C86803240 @default.
• W2020264563 hasIssue "2" @default.
• W2020264563 hasLocation W20202645631 @default.
• W2020264563 hasLocation W20202645632 @default.
• W2020264563 hasOpenAccess W2020264563 @default.
• W2020264563 hasPrimaryLocation W20202645631 @default.
• W2020264563 hasRelatedWork W1976889389 @default.
• W2020264563 hasRelatedWork W2020264563 @default.
• W2020264563 hasRelatedWork W2026512613 @default.

• next