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- W2020284795 abstract "A sensitive high-performance liquid chromatography method for vitamin K1 using normal-phase fractionation was updated in order to cope with the limited volume of blood samples obtained from newborns. The method combines sample clean-up, normal-phase fractionation with reversed-phase chromatography using post-column electrochemical reduction and fluorescence detection. It was possible to measure vitamin K1 concentration in at least 0.2 ml of (potentially lipemic) serum even at a level of 0.3 nmol/l. The normal-phase method was compared to the updated method. The updated method shows about a twenty-fold lower limit of detectability than the previously described method." @default.
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- W2020284795 date "1986-06-01" @default.
- W2020284795 modified "2023-09-24" @default.
- W2020284795 title "Quantitation of trans-vitamin K1 in small serum samples by off-line multidimensional liquid chromatography" @default.
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- W2020284795 doi "https://doi.org/10.1016/0009-8981(86)90297-4" @default.
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