FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020307261> ?p ?o ?g. }

• W2020307261 endingPage "1073" @default.
• W2020307261 startingPage "1065" @default.
• W2020307261 abstract "Six male Long-Evans rats were trained to self-administer 10% ethanol (v/v) during 30 min operant sessions. A licking response on an empty drinking tube resulted in the presentation of reinforcement from an automatic dipper. During the initiation of ethanol self-administration, a tone-light stimulus complex was paired with all ethanol presentations. When 10% ethanol maintained responding, guide cannulae aimed at the nucleus accumbens (NAcc) were implanted into the brain. The ability of the paired stimulus complex to reinforce a new operant response (i.e., a lever press) was then examined. To test for the development of the new response, responding on one lever resulted in presentation of only the paired tone-light stimulus complex (contingency-associated lever) while responding on an alternate lever had no programmed consequences (no contingency-associated lever). Prior to some new response sessions, amphetamine (5-20 microg/microl) was infused into the NAcc to examine the influence of dopamine on responding maintained by the stimulus complex. Ethanol intake during the sessions prior to new response testing averaged 0.49 +/- 0.07 g/g. During new response sessions no significant differences in lever pressure during no-drug conditions (control, sham, injection or vehicle injection) were observed between the contingency-associated and no contingency-associated levers. Intra-NAcc infusion of amphetamine (5-20 microg/microl) resulted in significant increases in lever pressing only on the contingency-associated lever. These data suggest that increasing NAcc dopamine levels with amphetamine enhanced the ability of the stimulus complex to function as a reinforcer. Further studies examining the ability of potentially more salient stimuli (i.e., taste of ethanol) to function as conditioned reinforcers associated with ethanol self-administration are warranted due to the apparent inability of the paired tone-light stimulus complex to function as a reinforcer without amphetamine-induced activation of the NAcc." @default.
• W2020307261 created "2016-06-24" @default.
• W2020307261 creator A5043934705 @default.
• W2020307261 creator A5050573426 @default.
• W2020307261 creator A5056120124 @default.
• W2020307261 date "1997-12-01" @default.
• W2020307261 modified "2023-10-14" @default.
• W2020307261 title "Intranucleus Accumbens Amphetamine Infusions Enhance Responding Maintained by a Stimulus Complex Paired With Oral Ethanol Self-Administration" @default.
• W2020307261 cites W150584151 @default.
• W2020307261 cites W1560866707 @default.
• W2020307261 cites W1604447261 @default.
• W2020307261 cites W1636089071 @default.
• W2020307261 cites W1884887148 @default.
• W2020307261 cites W1916131873 @default.
• W2020307261 cites W1963634631 @default.
• W2020307261 cites W1965660994 @default.
• W2020307261 cites W1968143328 @default.
• W2020307261 cites W1970079826 @default.
• W2020307261 cites W1971474286 @default.
• W2020307261 cites W1971620345 @default.
• W2020307261 cites W1974524443 @default.
• W2020307261 cites W1975436677 @default.
• W2020307261 cites W1976196537 @default.
• W2020307261 cites W1981841185 @default.
• W2020307261 cites W1984110918 @default.
• W2020307261 cites W1988211152 @default.
• W2020307261 cites W1998592627 @default.
• W2020307261 cites W2005898154 @default.
• W2020307261 cites W2007591890 @default.
• W2020307261 cites W2011684184 @default.
• W2020307261 cites W2014415095 @default.
• W2020307261 cites W2015651101 @default.
• W2020307261 cites W2021496139 @default.
• W2020307261 cites W2022587323 @default.
• W2020307261 cites W2023612551 @default.
• W2020307261 cites W2024706758 @default.
• W2020307261 cites W2025421654 @default.
• W2020307261 cites W2031217548 @default.
• W2020307261 cites W2031739149 @default.
• W2020307261 cites W2033123455 @default.
• W2020307261 cites W2035507667 @default.
• W2020307261 cites W2035982838 @default.
• W2020307261 cites W2037653067 @default.
• W2020307261 cites W2038816013 @default.
• W2020307261 cites W2039680594 @default.
• W2020307261 cites W2040185300 @default.
• W2020307261 cites W2044733617 @default.
• W2020307261 cites W2045741859 @default.
• W2020307261 cites W2048103417 @default.
• W2020307261 cites W2050290616 @default.
• W2020307261 cites W2050554540 @default.
• W2020307261 cites W2057893051 @default.
• W2020307261 cites W2063623448 @default.
• W2020307261 cites W2064745647 @default.
• W2020307261 cites W2066964020 @default.
• W2020307261 cites W2070554926 @default.
• W2020307261 cites W2071029430 @default.
• W2020307261 cites W2072886182 @default.
• W2020307261 cites W2073346596 @default.
• W2020307261 cites W2079322728 @default.
• W2020307261 cites W2085461481 @default.
• W2020307261 cites W2088885633 @default.
• W2020307261 cites W2091733627 @default.
• W2020307261 cites W2108873037 @default.
• W2020307261 cites W2121603624 @default.
• W2020307261 cites W2125215500 @default.
• W2020307261 cites W2131795377 @default.
• W2020307261 cites W2156782574 @default.
• W2020307261 cites W2163815564 @default.
• W2020307261 cites W2317279774 @default.
• W2020307261 cites W2322160768 @default.
• W2020307261 cites W2424733156 @default.
• W2020307261 cites W2468490037 @default.
• W2020307261 cites W591258448 @default.
• W2020307261 doi "https://doi.org/10.1016/s0091-3057(97)00310-9" @default.
• W2020307261 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9408215" @default.
• W2020307261 hasPublicationYear "1997" @default.
• W2020307261 type Work @default.
• W2020307261 sameAs 2020307261 @default.
• W2020307261 citedByCount "28" @default.
• W2020307261 countsByYear W20203072612013 @default.
• W2020307261 countsByYear W20203072612017 @default.
• W2020307261 crossrefType "journal-article" @default.
• W2020307261 hasAuthorship W2020307261A5043934705 @default.
• W2020307261 hasAuthorship W2020307261A5050573426 @default.
• W2020307261 hasAuthorship W2020307261A5056120124 @default.
• W2020307261 hasConcept C107524782 @default.
• W2020307261 hasConcept C121332964 @default.
• W2020307261 hasConcept C138496976 @default.
• W2020307261 hasConcept C15744967 @default.
• W2020307261 hasConcept C169760540 @default.
• W2020307261 hasConcept C180747234 @default.
• W2020307261 hasConcept C2776552330 @default.
• W2020307261 hasConcept C2777193897 @default.
• W2020307261 hasConcept C2778555786 @default.
• W2020307261 hasConcept C2779547902 @default.
• W2020307261 hasConcept C2779918689 @default.
• W2020307261 hasConcept C2780723003 @default.

• next