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- W2020346980 abstract "Biologically active eicosanoids are substances that initiate, aggravate, or sustain thrombosis and inflammation. Prominent in this regard are thromboxane A2, a potent coronary vasoconstrictor and platelet-aggregating factor and leukotriene B4, a potent leukocyte chemotactic agent. Pharmacologic restraint of their formation may be beneficial. Recent research on the natural regulation of their formation recognizes the importance of two processes: the genesis of enzymes and proteins that amplify eicosanoid formation and the “suicide” inactivation that accompanies this formation. The balance of genesis-“suicide” of eicosanoid biosynthetic enzymes offers a new way to raise questions about the role of eicosanoids in cardiac disorders." @default.
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- W2020346980 title "Genesis and “suicide” of eicosanoid biosynthetic enzymes" @default.
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- W2020346980 doi "https://doi.org/10.1016/1050-1738(91)90015-7" @default.
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