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• W2020349051 abstract "We compared the lipophilicity and toxicity of the four flavonols, galangin, kaempferol, quercetin and myrice-tin, which respectively have no, one, two and three hydroxyl groups on the B-ring. The lipophilicity was in the order of myricetin < quercetin < kaempferol < galan-gin. The cytotoxicity determined by a colony-formation assay with Chinese hamster lung fibroblast V79 cells was in the order of quercetin < kaempferol < galangin<myricetin. Apart from myricetin, the order of lipophilicity was the same as that of cytotoxicity, implying that the cytotoxicity was attributable to the lipophilicity. The cytotoxicity of myricetin was attributable to the hydrogen peroxide formed by autoxidation." @default.
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• W2020349051 date "2001-01-01" @default.
• W2020349051 modified "2023-10-18" @default.
• W2020349051 title "Role of Lipophilicity and Hydrogen Peroxide Formation in the Cytotoxicity of Flavonols" @default.
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• W2020349051 doi "https://doi.org/10.1271/bbb.65.1227" @default.
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