Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020349900> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2020349900 abstract "This study attempted to visualize serotonin (5-HT)-immunoreactive (IR) neurons in the hypothalamus of intact fetuses (E18) and neonatal rats (P9) as well as after their pretreatment with some drugs interfering with the 5-HT metabolism and uptake in the serotoninergic neurons (L-tryptophan, pargyline, 5-hydroxytryptophan, fluoxetine). The 5-HT-IR cells were not observed in the hypothalamus of normal, untreated fetuses and neonatal rats. However, two large accumulations of 5-HT-IR neurons appeared in the anterolateral hypothalamus and in the dorsomedial nucleus after the subsequent injections of the monoamine oxidase inhibitor, pargyline, and the amino acid precursor of the 5-HT synthesis, L-tryptophan. A significantly less intensive reaction was observed after injections either of the second precursor of the 5-HT synthesis, 5-hydroxytryptophan instead of L-tryptophan, or pargyline only. Immunostaining, provoked by the pargyline and L-tryptophan pretreatment, was completely blocked by the injection of the specific 5-HT uptake inhibitor, fluoxetine. It means that the 5-HT immunostaining of the hypothalamic neurons may be accounted for by their capacity to take up specifically 5-HT from the environment rather than by its intraneuronal synthesis from L-tryptophan. Nevertheless, the 5-HT synthesis from 5-hydroxytryptophan in these cells cannot be excluded. The uptake of extracellular 5-HT into catecholaminergic neurons can be excluded as nomifensine, the specific inhibitor of the uptake to these neurons, did not modify the immunostaining." @default.
- W2020349900 created "2016-06-24" @default.
- W2020349900 creator A5004432345 @default.
- W2020349900 creator A5007144325 @default.
- W2020349900 creator A5014697593 @default.
- W2020349900 creator A5034271746 @default.
- W2020349900 creator A5076985754 @default.
- W2020349900 date "1989-04-01" @default.
- W2020349900 modified "2023-09-27" @default.
- W2020349900 title "On the distribution and morpho-functional characteristics of 5-HT-immunoreactive cells in the hypothalamus of fetuses and neonatal rats" @default.
- W2020349900 cites W1970196290 @default.
- W2020349900 cites W1989015688 @default.
- W2020349900 cites W2000120439 @default.
- W2020349900 cites W2011342020 @default.
- W2020349900 cites W2023140695 @default.
- W2020349900 cites W2033124222 @default.
- W2020349900 cites W2043474405 @default.
- W2020349900 cites W2052969198 @default.
- W2020349900 cites W2053955290 @default.
- W2020349900 cites W2082188651 @default.
- W2020349900 doi "https://doi.org/10.1016/0165-3806(89)90287-3" @default.
- W2020349900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2720956" @default.
- W2020349900 hasPublicationYear "1989" @default.
- W2020349900 type Work @default.
- W2020349900 sameAs 2020349900 @default.
- W2020349900 citedByCount "27" @default.
- W2020349900 countsByYear W20203499002012 @default.
- W2020349900 countsByYear W20203499002013 @default.
- W2020349900 countsByYear W20203499002016 @default.
- W2020349900 countsByYear W20203499002018 @default.
- W2020349900 countsByYear W20203499002019 @default.
- W2020349900 crossrefType "journal-article" @default.
- W2020349900 hasAuthorship W2020349900A5004432345 @default.
- W2020349900 hasAuthorship W2020349900A5007144325 @default.
- W2020349900 hasAuthorship W2020349900A5014697593 @default.
- W2020349900 hasAuthorship W2020349900A5034271746 @default.
- W2020349900 hasAuthorship W2020349900A5076985754 @default.
- W2020349900 hasConcept C126322002 @default.
- W2020349900 hasConcept C134018914 @default.
- W2020349900 hasConcept C170493617 @default.
- W2020349900 hasConcept C181199279 @default.
- W2020349900 hasConcept C187714386 @default.
- W2020349900 hasConcept C204232928 @default.
- W2020349900 hasConcept C2775864247 @default.
- W2020349900 hasConcept C2775951788 @default.
- W2020349900 hasConcept C2776024655 @default.
- W2020349900 hasConcept C2776824294 @default.
- W2020349900 hasConcept C2777003273 @default.
- W2020349900 hasConcept C2777067607 @default.
- W2020349900 hasConcept C2778630814 @default.
- W2020349900 hasConcept C37000724 @default.
- W2020349900 hasConcept C4224716 @default.
- W2020349900 hasConcept C513476851 @default.
- W2020349900 hasConcept C55493867 @default.
- W2020349900 hasConcept C71924100 @default.
- W2020349900 hasConcept C86803240 @default.
- W2020349900 hasConceptScore W2020349900C126322002 @default.
- W2020349900 hasConceptScore W2020349900C134018914 @default.
- W2020349900 hasConceptScore W2020349900C170493617 @default.
- W2020349900 hasConceptScore W2020349900C181199279 @default.
- W2020349900 hasConceptScore W2020349900C187714386 @default.
- W2020349900 hasConceptScore W2020349900C204232928 @default.
- W2020349900 hasConceptScore W2020349900C2775864247 @default.
- W2020349900 hasConceptScore W2020349900C2775951788 @default.
- W2020349900 hasConceptScore W2020349900C2776024655 @default.
- W2020349900 hasConceptScore W2020349900C2776824294 @default.
- W2020349900 hasConceptScore W2020349900C2777003273 @default.
- W2020349900 hasConceptScore W2020349900C2777067607 @default.
- W2020349900 hasConceptScore W2020349900C2778630814 @default.
- W2020349900 hasConceptScore W2020349900C37000724 @default.
- W2020349900 hasConceptScore W2020349900C4224716 @default.
- W2020349900 hasConceptScore W2020349900C513476851 @default.
- W2020349900 hasConceptScore W2020349900C55493867 @default.
- W2020349900 hasConceptScore W2020349900C71924100 @default.
- W2020349900 hasConceptScore W2020349900C86803240 @default.
- W2020349900 hasLocation W20203499001 @default.
- W2020349900 hasLocation W20203499002 @default.
- W2020349900 hasOpenAccess W2020349900 @default.
- W2020349900 hasPrimaryLocation W20203499001 @default.
- W2020349900 hasRelatedWork W1972143280 @default.
- W2020349900 hasRelatedWork W1973688077 @default.
- W2020349900 hasRelatedWork W1982449770 @default.
- W2020349900 hasRelatedWork W2017519523 @default.
- W2020349900 hasRelatedWork W2020349900 @default.
- W2020349900 hasRelatedWork W2037605425 @default.
- W2020349900 hasRelatedWork W2074904241 @default.
- W2020349900 hasRelatedWork W2134774734 @default.
- W2020349900 hasRelatedWork W2413438794 @default.
- W2020349900 hasRelatedWork W2420504810 @default.
- W2020349900 isParatext "false" @default.
- W2020349900 isRetracted "false" @default.
- W2020349900 magId "2020349900" @default.
- W2020349900 workType "article" @default.