FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020366176> ?p ?o ?g. }

• W2020366176 endingPage "2279" @default.
• W2020366176 startingPage "2274" @default.
• W2020366176 abstract "We previously reported identifying SOX6 as a glioma antigen by serological screening using a testis cDNA library. Its preferential expression and frequent IgG responses in glioma patients indicate that SOX6 may be a useful target for immunotherapy. To examine whether cytotoxic T-lymphocyte (CTL) responses specific for SOX6 to destroy glioma can be generated in vivo, we treated glioma-bearing mice by vaccination with a plasmid DNA encoding murine full-length SOX6 protein. Following SOX6-DNA vaccination, CTLs specific for SOX6-expressing glioma cells were induced, while normal autologous-cells that had restrictedly expressed SOX6 during embryogenesis were not destroyed. Furthermore, DNA vaccination with SOX6 exerted protective and therapeutic antitumor responses in the glioma-bearing mice. This antitumor activity was abrogated by the depletion of CD4 positive T cells and/or CD8 positive T cells. These results suggest that the SOX6 protein has multiple CTL and helper epitopes to induce antitumor activity and the effectiveness of SOX6-DNA vaccine for the prevention and treatment of glioma. © 2008 Wiley-Liss, Inc." @default.
• W2020366176 created "2016-06-24" @default.
• W2020366176 creator A5011214922 @default.
• W2020366176 creator A5012902280 @default.
• W2020366176 creator A5055290282 @default.
• W2020366176 creator A5057070343 @default.
• W2020366176 creator A5083346908 @default.
• W2020366176 creator A5085432609 @default.
• W2020366176 date "2008-01-25" @default.
• W2020366176 modified "2023-10-03" @default.
• W2020366176 title "Induction of protective and therapeutic antitumor immunity by a DNA vaccine with a glioma antigen, SOX6" @default.
• W2020366176 cites W1831319429 @default.
• W2020366176 cites W1882056780 @default.
• W2020366176 cites W1965874459 @default.
• W2020366176 cites W1967294655 @default.
• W2020366176 cites W1983285913 @default.
• W2020366176 cites W1998213298 @default.
• W2020366176 cites W2002709279 @default.
• W2020366176 cites W2017828665 @default.
• W2020366176 cites W2021840830 @default.
• W2020366176 cites W2032914811 @default.
• W2020366176 cites W2036651654 @default.
• W2020366176 cites W2040594411 @default.
• W2020366176 cites W2042708573 @default.
• W2020366176 cites W2049848159 @default.
• W2020366176 cites W2057492575 @default.
• W2020366176 cites W2062767336 @default.
• W2020366176 cites W2064787481 @default.
• W2020366176 cites W2068072044 @default.
• W2020366176 cites W2078782153 @default.
• W2020366176 cites W2099113749 @default.
• W2020366176 cites W2102047286 @default.
• W2020366176 cites W2114754387 @default.
• W2020366176 cites W2162332541 @default.
• W2020366176 cites W4211173076 @default.
• W2020366176 doi "https://doi.org/10.1002/ijc.23366" @default.
• W2020366176 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18224680" @default.
• W2020366176 hasPublicationYear "2008" @default.
• W2020366176 type Work @default.
• W2020366176 sameAs 2020366176 @default.
• W2020366176 citedByCount "18" @default.
• W2020366176 countsByYear W20203661762012 @default.
• W2020366176 countsByYear W20203661762013 @default.
• W2020366176 countsByYear W20203661762014 @default.
• W2020366176 countsByYear W20203661762020 @default.
• W2020366176 countsByYear W20203661762021 @default.
• W2020366176 countsByYear W20203661762022 @default.
• W2020366176 crossrefType "journal-article" @default.
• W2020366176 hasAuthorship W2020366176A5011214922 @default.
• W2020366176 hasAuthorship W2020366176A5012902280 @default.
• W2020366176 hasAuthorship W2020366176A5055290282 @default.
• W2020366176 hasAuthorship W2020366176A5057070343 @default.
• W2020366176 hasAuthorship W2020366176A5083346908 @default.
• W2020366176 hasAuthorship W2020366176A5085432609 @default.
• W2020366176 hasBestOaLocation W20203661761 @default.
• W2020366176 hasConcept C147483822 @default.
• W2020366176 hasConcept C147969180 @default.
• W2020366176 hasConcept C154317977 @default.
• W2020366176 hasConcept C167508917 @default.
• W2020366176 hasConcept C167672396 @default.
• W2020366176 hasConcept C195616568 @default.
• W2020366176 hasConcept C202751555 @default.
• W2020366176 hasConcept C203014093 @default.
• W2020366176 hasConcept C2777701055 @default.
• W2020366176 hasConcept C2778227246 @default.
• W2020366176 hasConcept C2780801004 @default.
• W2020366176 hasConcept C502942594 @default.
• W2020366176 hasConcept C54355233 @default.
• W2020366176 hasConcept C86803240 @default.
• W2020366176 hasConcept C8891405 @default.
• W2020366176 hasConceptScore W2020366176C147483822 @default.
• W2020366176 hasConceptScore W2020366176C147969180 @default.
• W2020366176 hasConceptScore W2020366176C154317977 @default.
• W2020366176 hasConceptScore W2020366176C167508917 @default.
• W2020366176 hasConceptScore W2020366176C167672396 @default.
• W2020366176 hasConceptScore W2020366176C195616568 @default.
• W2020366176 hasConceptScore W2020366176C202751555 @default.
• W2020366176 hasConceptScore W2020366176C203014093 @default.
• W2020366176 hasConceptScore W2020366176C2777701055 @default.
• W2020366176 hasConceptScore W2020366176C2778227246 @default.
• W2020366176 hasConceptScore W2020366176C2780801004 @default.
• W2020366176 hasConceptScore W2020366176C502942594 @default.
• W2020366176 hasConceptScore W2020366176C54355233 @default.
• W2020366176 hasConceptScore W2020366176C86803240 @default.
• W2020366176 hasConceptScore W2020366176C8891405 @default.
• W2020366176 hasIssue "10" @default.
• W2020366176 hasLocation W20203661761 @default.
• W2020366176 hasLocation W20203661762 @default.
• W2020366176 hasOpenAccess W2020366176 @default.
• W2020366176 hasPrimaryLocation W20203661761 @default.
• W2020366176 hasRelatedWork W2014702019 @default.
• W2020366176 hasRelatedWork W2016031396 @default.
• W2020366176 hasRelatedWork W2018916009 @default.
• W2020366176 hasRelatedWork W2042955728 @default.
• W2020366176 hasRelatedWork W2052483994 @default.
• W2020366176 hasRelatedWork W2053103268 @default.
• W2020366176 hasRelatedWork W2058710260 @default.
• W2020366176 hasRelatedWork W2362411527 @default.

• next