Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020398706> ?p ?o ?g. }
- W2020398706 endingPage "165" @default.
- W2020398706 startingPage "161" @default.
- W2020398706 abstract "The effects of two ligands with previously established high and selective potency for metabotropic glutamate receptors (mGlu receptors) group II have been investigated on the high frequency stimulation (HFS) induced long-term potentiation of the field excitatory postsynaptic potential (EPSP) in the dentate gyrus of the rat hippocampus in vitro. The ligands investigated were (2S,1′S,2′S,3′R)-2-(2″-carboxy-3′-phenylcyclopropyl)glycine (PCCG-IV) and (R,S)-α-methyl-4-tetrazolylphenylglycine (MTPG). PCCG-IV (10 μM) strongly inhibited the induction of long-term potentiation of the field EPSP by high frequency stimulation. MTPG (50 μM) did not inhibit the induction of long-term potentiation, but prevented the inhibition of long-term potentiation induction by PCCG-IV. The inhibition of long-term potentiation induction by PCCG-IV is suggested to be due to an agonistic action on mGlu receptor group II, probably mGlu3 receptor, as the inhibition of long-term potentiation can be reversed by the application of MTPG, a well-known selective and potent antagonist of mGlu receptor group II." @default.
- W2020398706 created "2016-06-24" @default.
- W2020398706 creator A5002624924 @default.
- W2020398706 creator A5036505729 @default.
- W2020398706 creator A5067532394 @default.
- W2020398706 creator A5089447965 @default.
- W2020398706 date "1997-08-01" @default.
- W2020398706 modified "2023-10-18" @default.
- W2020398706 title "PCCG-IV inhibits the induction of long-term potentiation in the dentate gyrus in vitro" @default.
- W2020398706 cites W1951891496 @default.
- W2020398706 cites W1963963391 @default.
- W2020398706 cites W1964281319 @default.
- W2020398706 cites W1965281982 @default.
- W2020398706 cites W1973756897 @default.
- W2020398706 cites W1982543967 @default.
- W2020398706 cites W1990407514 @default.
- W2020398706 cites W2003040206 @default.
- W2020398706 cites W2003058141 @default.
- W2020398706 cites W2004668023 @default.
- W2020398706 cites W2005432693 @default.
- W2020398706 cites W2015778209 @default.
- W2020398706 cites W2019640491 @default.
- W2020398706 cites W2020689125 @default.
- W2020398706 cites W2025267803 @default.
- W2020398706 cites W2027610709 @default.
- W2020398706 cites W2033745315 @default.
- W2020398706 cites W2035245157 @default.
- W2020398706 cites W2044157568 @default.
- W2020398706 cites W2069951879 @default.
- W2020398706 cites W2074873783 @default.
- W2020398706 cites W2085673544 @default.
- W2020398706 cites W2087080875 @default.
- W2020398706 cites W2091281983 @default.
- W2020398706 cites W2094145001 @default.
- W2020398706 cites W2183530574 @default.
- W2020398706 cites W2277185635 @default.
- W2020398706 cites W2404191901 @default.
- W2020398706 cites W2409911747 @default.
- W2020398706 cites W2413148011 @default.
- W2020398706 doi "https://doi.org/10.1016/s0014-2999(97)01079-0" @default.
- W2020398706 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9286617" @default.
- W2020398706 hasPublicationYear "1997" @default.
- W2020398706 type Work @default.
- W2020398706 sameAs 2020398706 @default.
- W2020398706 citedByCount "6" @default.
- W2020398706 crossrefType "journal-article" @default.
- W2020398706 hasAuthorship W2020398706A5002624924 @default.
- W2020398706 hasAuthorship W2020398706A5036505729 @default.
- W2020398706 hasAuthorship W2020398706A5067532394 @default.
- W2020398706 hasAuthorship W2020398706A5089447965 @default.
- W2020398706 hasConcept C112592302 @default.
- W2020398706 hasConcept C169760540 @default.
- W2020398706 hasConcept C170493617 @default.
- W2020398706 hasConcept C17077164 @default.
- W2020398706 hasConcept C185592680 @default.
- W2020398706 hasConcept C197341189 @default.
- W2020398706 hasConcept C24998067 @default.
- W2020398706 hasConcept C25274449 @default.
- W2020398706 hasConcept C26702167 @default.
- W2020398706 hasConcept C2776328245 @default.
- W2020398706 hasConcept C2776464000 @default.
- W2020398706 hasConcept C2781161787 @default.
- W2020398706 hasConcept C49051014 @default.
- W2020398706 hasConcept C55493867 @default.
- W2020398706 hasConcept C61174792 @default.
- W2020398706 hasConcept C67018056 @default.
- W2020398706 hasConcept C86803240 @default.
- W2020398706 hasConcept C98274493 @default.
- W2020398706 hasConceptScore W2020398706C112592302 @default.
- W2020398706 hasConceptScore W2020398706C169760540 @default.
- W2020398706 hasConceptScore W2020398706C170493617 @default.
- W2020398706 hasConceptScore W2020398706C17077164 @default.
- W2020398706 hasConceptScore W2020398706C185592680 @default.
- W2020398706 hasConceptScore W2020398706C197341189 @default.
- W2020398706 hasConceptScore W2020398706C24998067 @default.
- W2020398706 hasConceptScore W2020398706C25274449 @default.
- W2020398706 hasConceptScore W2020398706C26702167 @default.
- W2020398706 hasConceptScore W2020398706C2776328245 @default.
- W2020398706 hasConceptScore W2020398706C2776464000 @default.
- W2020398706 hasConceptScore W2020398706C2781161787 @default.
- W2020398706 hasConceptScore W2020398706C49051014 @default.
- W2020398706 hasConceptScore W2020398706C55493867 @default.
- W2020398706 hasConceptScore W2020398706C61174792 @default.
- W2020398706 hasConceptScore W2020398706C67018056 @default.
- W2020398706 hasConceptScore W2020398706C86803240 @default.
- W2020398706 hasConceptScore W2020398706C98274493 @default.
- W2020398706 hasIssue "2" @default.
- W2020398706 hasLocation W20203987061 @default.
- W2020398706 hasLocation W20203987062 @default.
- W2020398706 hasOpenAccess W2020398706 @default.
- W2020398706 hasPrimaryLocation W20203987061 @default.
- W2020398706 hasRelatedWork W1978922003 @default.
- W2020398706 hasRelatedWork W2020398706 @default.
- W2020398706 hasRelatedWork W2031417454 @default.
- W2020398706 hasRelatedWork W2044157568 @default.
- W2020398706 hasRelatedWork W2048465471 @default.
- W2020398706 hasRelatedWork W2088069957 @default.
- W2020398706 hasRelatedWork W2104964311 @default.