Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020444027> ?p ?o ?g. }
- W2020444027 endingPage "5" @default.
- W2020444027 startingPage "1" @default.
- W2020444027 abstract "The main goal of the present paper was to examine the influence of the replacement of γ-Glu moiety to α-Glu in glutathione and in its antioxidative tetrapeptidic analogue UPF1 (Tyr(Me)-γ-Glu-Cys-Gly), resulting in α-GSH and UPF17 (Tyr(Me)-Glu-Cys-Gly), on the antioxidative defense system in K562 cells. UPF1 and GSH increased while UPF17 and α-GSH decreased the activity of CuZnSOD in K562 cells, at peptide concentration of 10 μM by 42% and 38% or 35% and 24%, respectively. After three-hour incubation, UPF1 increased and UPF17 decreased the intracellular level of total GSH. Additionally, it was shown that UPF1 is not degraded by γ-glutamyltranspeptidase, which performs glutathione breakdown. These results indicate that effective antioxidative character of peptides does not depend only on the reactivity of the thiol group, but also of the other functional groups, and on the spatial structure of peptides." @default.
- W2020444027 created "2016-06-24" @default.
- W2020444027 creator A5004798207 @default.
- W2020444027 creator A5031145843 @default.
- W2020444027 creator A5048840636 @default.
- W2020444027 creator A5080284238 @default.
- W2020444027 creator A5082841637 @default.
- W2020444027 creator A5088385522 @default.
- W2020444027 date "2012-02-15" @default.
- W2020444027 modified "2023-09-30" @default.
- W2020444027 title "Diverse Effects of Glutathione and UPF Peptides on Antioxidant Defense System in Human Erythroleukemia Cells K562" @default.
- W2020444027 cites W1479500 @default.
- W2020444027 cites W1775749144 @default.
- W2020444027 cites W1969789360 @default.
- W2020444027 cites W1985062061 @default.
- W2020444027 cites W1990185228 @default.
- W2020444027 cites W1995644783 @default.
- W2020444027 cites W2001934912 @default.
- W2020444027 cites W2007064404 @default.
- W2020444027 cites W2014352102 @default.
- W2020444027 cites W2028683861 @default.
- W2020444027 cites W2039385370 @default.
- W2020444027 cites W2049816734 @default.
- W2020444027 cites W2050953074 @default.
- W2020444027 cites W2058456593 @default.
- W2020444027 cites W2073803579 @default.
- W2020444027 cites W2085150103 @default.
- W2020444027 cites W2086119574 @default.
- W2020444027 cites W2093333026 @default.
- W2020444027 cites W2095532750 @default.
- W2020444027 cites W2111150708 @default.
- W2020444027 cites W2135890578 @default.
- W2020444027 cites W2143007491 @default.
- W2020444027 cites W2149907341 @default.
- W2020444027 cites W2151272921 @default.
- W2020444027 cites W2156421011 @default.
- W2020444027 cites W2168024298 @default.
- W2020444027 cites W2340377903 @default.
- W2020444027 doi "https://doi.org/10.1155/2012/124163" @default.
- W2020444027 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3348524" @default.
- W2020444027 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22611414" @default.
- W2020444027 hasPublicationYear "2012" @default.
- W2020444027 type Work @default.
- W2020444027 sameAs 2020444027 @default.
- W2020444027 citedByCount "8" @default.
- W2020444027 countsByYear W20204440272013 @default.
- W2020444027 countsByYear W20204440272014 @default.
- W2020444027 countsByYear W20204440272015 @default.
- W2020444027 countsByYear W20204440272019 @default.
- W2020444027 countsByYear W20204440272023 @default.
- W2020444027 crossrefType "journal-article" @default.
- W2020444027 hasAuthorship W2020444027A5004798207 @default.
- W2020444027 hasAuthorship W2020444027A5031145843 @default.
- W2020444027 hasAuthorship W2020444027A5048840636 @default.
- W2020444027 hasAuthorship W2020444027A5080284238 @default.
- W2020444027 hasAuthorship W2020444027A5082841637 @default.
- W2020444027 hasAuthorship W2020444027A5088385522 @default.
- W2020444027 hasBestOaLocation W20204440271 @default.
- W2020444027 hasConcept C1491633281 @default.
- W2020444027 hasConcept C171122931 @default.
- W2020444027 hasConcept C181199279 @default.
- W2020444027 hasConcept C185592680 @default.
- W2020444027 hasConcept C25642318 @default.
- W2020444027 hasConcept C2778004101 @default.
- W2020444027 hasConcept C2779281246 @default.
- W2020444027 hasConcept C2781324293 @default.
- W2020444027 hasConcept C538909803 @default.
- W2020444027 hasConcept C55493867 @default.
- W2020444027 hasConcept C79879829 @default.
- W2020444027 hasConceptScore W2020444027C1491633281 @default.
- W2020444027 hasConceptScore W2020444027C171122931 @default.
- W2020444027 hasConceptScore W2020444027C181199279 @default.
- W2020444027 hasConceptScore W2020444027C185592680 @default.
- W2020444027 hasConceptScore W2020444027C25642318 @default.
- W2020444027 hasConceptScore W2020444027C2778004101 @default.
- W2020444027 hasConceptScore W2020444027C2779281246 @default.
- W2020444027 hasConceptScore W2020444027C2781324293 @default.
- W2020444027 hasConceptScore W2020444027C538909803 @default.
- W2020444027 hasConceptScore W2020444027C55493867 @default.
- W2020444027 hasConceptScore W2020444027C79879829 @default.
- W2020444027 hasFunder F4320321018 @default.
- W2020444027 hasLocation W20204440271 @default.
- W2020444027 hasLocation W20204440272 @default.
- W2020444027 hasLocation W20204440273 @default.
- W2020444027 hasLocation W20204440274 @default.
- W2020444027 hasOpenAccess W2020444027 @default.
- W2020444027 hasPrimaryLocation W20204440271 @default.
- W2020444027 hasRelatedWork W1823471322 @default.
- W2020444027 hasRelatedWork W1968537115 @default.
- W2020444027 hasRelatedWork W1989749016 @default.
- W2020444027 hasRelatedWork W2005314473 @default.
- W2020444027 hasRelatedWork W2008157816 @default.
- W2020444027 hasRelatedWork W2010479937 @default.
- W2020444027 hasRelatedWork W2017010858 @default.
- W2020444027 hasRelatedWork W2085606485 @default.
- W2020444027 hasRelatedWork W2383606795 @default.
- W2020444027 hasRelatedWork W2188619025 @default.
- W2020444027 hasVolume "2012" @default.