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• W2020489745 abstract "• In an attempt to elucidate the molecular mechanisms of Melampsora rust resistance in Populus trichocarpa, we have mapped two resistance loci, MXC3 and MER, and intensively characterized the flanking genomic sequence for the MXC3 locus and the level of linkage disequilibrium (LD) in natural populations. • We used an interspecific backcross pedigree and a genetic map that was highly saturated with AFLP and SSR markers, and assembled shotgun-sequence data in the region containing markers linked to MXC3. • The two loci were mapped to different linkage groups. Linkage disequilibrium for MXC3 was confined to two closely linked regions spanning 34 and 16 kb, respectively. The MXC3 region also contained six disease-resistance candidate genes. • The MER and MXC3 loci are clearly distinct, and may have different mechanisms of resistance, as different classes of putative resistance genes were present near each locus. The suppressed recombination previously observed in the MXC3 region was possibly caused by extensive hemizygous rearrangements confined to the original parent tree. The relatively low observed LD may facilitate association studies using candidate genes for rust resistance, but will probably inhibit marker-aided selection." @default.
• W2020489745 created "2016-06-24" @default.
• W2020489745 creator A5057728704 @default.
• W2020489745 creator A5071521048 @default.
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• W2020489745 creator A5080353055 @default.
• W2020489745 creator A5085423503 @default.
• W2020489745 date "2004-08-12" @default.
• W2020489745 modified "2023-10-11" @default.
• W2020489745 title "Genetic and physical mapping of <i>Melampsora</i> rust resistance genes in <i>Populus</i> and characterization of linkage disequilibrium and flanking genomic sequence" @default.
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• W2020489745 doi "https://doi.org/10.1111/j.1469-8137.2004.01161.x" @default.
• W2020489745 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33873470" @default.
• W2020489745 hasPublicationYear "2004" @default.
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